IUPAC Name: 2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl]-4,5-diethyl-1,2,4-triazol-3-one hydrochloride
Synonyms of Etoperidone hydrochloride (CAS NO.57775-22-1) : 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3,4-diethyl-delta(sup 2)-1,2,4-triazolin-5-one monohydrochloride ; 3H-1,2,4-Triazol-3-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-4,5-diethyl-2,4-dihydro-, monohydrochloride ; Axiomin ; Clopradone, trazolinone ; Depracer ; Etonin ; Etoperidone HCl ; Etoperidone hydrochloride ; Etoran ;Tropene ; 2-(3-(4-(3-Chlorophenyl)piperazin-1-yl)propyl)-4,5-diethyl-2,4-dihydro-3H-1,2,4-triazol-3-one monohydrochloride
CAS NO:57775-22-1
Molecular Formula:C19H29Cl2N5O
Molecular Weight :414.372460 g/mol
Molecular Structure :
EINECS: 260-942-5
Flash Point: 255.6 °C
Enthalpy of Vaporization: 76.73 kJ/mol
Boiling Point: 499 °C at 760 mmHg
Vapour Pressure: 4.3E-10 mmHg at 25°C
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 135mg/kg (135mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 417, 1978. |
mouse | LD50 | intravenous | 68mg/kg (68mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 294, 1979. |
mouse | LD50 | oral | 518mg/kg (518mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 294, 1979. |
rat | LD50 | intraperitoneal | 120mg/kg (120mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 417, 1978. |
rat | LD50 | intravenous | 62mg/kg (62mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 417, 1978. | |
rat | LD50 | oral | 397mg/kg (397mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 294, 1979. |
rat | LD50 | subcutaneous | 543mg/kg (543mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 294, 1979. |
Poison by ingestion, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When Etoperidone hydrochloride (CAS NO.57775-22-1) is heated to decomposition ,it emits very toxic fumes of Cl− and NOx.
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