IUPAC Name: (R)-[(4S,5R,7S)-5-Ethyl-1-azabicyclo[2.2.2]octan-7-yl]-[6-(3-methylbutoxy)quinolin-4-yl]methanol dihydrochloride
Synonyms of Eucupin dihyrdochloride (CAS NO.18984-80-0) : 6-Quinolinol, 4-((1-methoxybutoxy)(5-vinyl-2-quinuclidinyl)methyl)-, dihydrochloride ; Eucupin dihydrochloride ; Euprocin HCl ; Euprocin hydrochloride ; Isoamyl hydrocupreine dihydrochloride ; O(sup 6)'Isopentylhydrocupreinedihydrochloride ; Cinchonan-9-ol, 10,11-dihydro-6'-(3-methylbutoxy)-,
dihydrochloride, (8alpha,9R)- ; Hydrocupreine, O(Sup 6')-isopentyl-, dihydrochloride
InChI=1/C6H8O7.Eu/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+3/p-3
CAS NO:18984-80-0
Molecular Formula:C24H36Cl2N2O2
Molecular Weight :455.460840 g/mol
Molecular Structure :
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | intravenous | 6820ug/kg (6.82mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA BLOOD: OTHER CHANGES | Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 11, Pg. 257, 1920. |
cat | LDLo | subcutaneous | 50mg/kg (50mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD CARDIAC: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 11, Pg. 257, 1920. |
mouse | LDLo | subcutaneous | 300mg/kg (300mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD CARDIAC: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 11, Pg. 257, 1920. |
rat | LD50 | intravenous | 20mg/kg (20mg/kg) | Compilation of LD50 Values of New Drugs. | |
rat | LDLo | subcutaneous | 800mg/kg (800mg/kg) | Compilation of LD50 Values of New Drugs. |
Poison by ingestion and intravenous routes. Moderately toxic by subcutaneous route. When Eucupin dihyrdochloride (CAS NO.18984-80-0) is heated to decomposition ,it emits very toxic fumes of HCl and NOx.
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