-
Name
Febuprol
- EINECS 221-454-8
- CAS No. 3102-00-9
- Article Data10
- CAS DataBase
- Density 1.034 g/cm3
- Solubility
- Melting Point 25°C
- Formula C13H20 O3
- Boiling Point 346 °C at 760 mmHg
- Molecular Weight 224.3
- Flash Point 163.1 °C
- Transport Information
- Appearance
- Safety Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. Stimulates the production of bile by the liver. See also ETHERS. When heated to decomposition it emits acrid smoke and irritating fumes.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms 1-Phenoxy-3-butoxy-2-propanol;3-Butoxy-1-phenoxy-2-propanol; Febuprol; H 33; K 10033; NSC 30151; Valbil;Valbilan
- PSA 38.69000
- LogP 2.24300
Febuprol Chemical Properties
Molecular Formula: C13H20O3
Molecular Weight: 224.30
EINECS: 221-454-8
Density: 1.034 g/cm3
Flash Point: 163.1 °C
Index of Refraction: 1.502
CAS Registry Number: 3102-00-9
Enthalpy of Vaporization: 62.28 kJ/mol
Boiling Point: 346 °C at 760 mmHg
Vapour Pressure: 2.25E-05 mmHg at 25°C
IUPAC Name: 1-Butoxy-3-phenoxypropan-2-ol
Appearanceof 3-N-butoxy-1-phenoxy-2-propanol (CAS NO.3102-00-9): Colorless or slightly yellow transparent liquid
Solubility: Soluble in ether, methanol, anhydrous ethanol and acetone. almost insoluble in water.
Synonyms: (3-N-butoxy-2-hydroxypropyl)phenylether ; 1-Butoxy-3-phenoxy-2-propano ; 3-N-butoxy-1-phenoxy-2-propanol ; H-33 ; K-10033 ; 1-Butoxy-3-(phenoxy)propan-2-ol ; Febuprol
Following is the molecular structure of 3-N-butoxy-1-phenoxy-2-propanol (CAS NO.3102-00-9):
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Febuprol Uses
3-N-butoxy-1-phenoxy-2-propanol (CAS NO.3102-00-9) is a gallbladder drugs for the treatment of cholecystitis and cholelithiasis and postoperative hyperlipidemia, lipid dyspepsia, hepatitis embolism.
Febuprol Toxicity Data With Reference
| 1. | orl-rat LD50:2370 mg/kg | DRFUD4 Drugs of the Future. 3 (1978),191. | ||
| 2. | ipr-rat LD50:400 mg/kg | DRFUD4 Drugs of the Future. 3 (1978),191. | ||
| 3. | orl-mus LD50:3050 mg/kg | DRFUD4 Drugs of the Future. 3 (1978),191. | ||
| 4. | ipr-mus LD50:436 mg/kg | DRFUD4 Drugs of the Future. 3 (1978),191. | ||
| 5. | orl-dog LD50:500 mg/kg | DRFUD4 Drugs of the Future. 3 (1978),191. | ||
| 6. | ivn-dog LD50:150 mg/kg | DRFUD4 Drugs of the Future. 3 (1978),191. |
Febuprol Safety Profile
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. Stimulates the production of bile by the liver. When heated to decomposition it emits acrid smoke and irritating fumes.
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