Product Name

  • Name

    FEMOXETINE HYDROCHLORIDE

  • EINECS
  • CAS No. 56222-04-9
  • Density
  • Solubility
  • Melting Point
  • Formula C20H25NO2•ClH
  • Boiling Point
  • Molecular Weight 347.92
  • Flash Point
  • Transport Information
  • Appearance
  • Safety Human toxic effects by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.
  • Risk Codes
  • Molecular Structure Molecular Structure of 56222-04-9 (FEMOXETINE HYDROCHLORIDE )
  • Hazard Symbols
  • Synonyms
  • PSA
  • LogP

Femoxetine hydrochloride Chemical Properties

IUPAC Name: (3R,4S)-3-[(4-Methoxyphenoxy)methyl]-1-methyl-4-phenylpiperidine hydrochloride
Synonyms of Femoxetine hydrochloride (CAS NO.56222-04-9) : (3R-trans)-3-((4-Methoxyphenoxy)methyl)-1-methyl-4-phenylpiperidine hydrochloride ; Femoxetine HCl ; Femoxetine hydrochloride ; Malexil ; Piperidine, 3-((4-methoxyphenoxy)methyl)-1-methyl-4-phenyl-, hydrochloride, (3R-trans)-
InChI: InChI=1/C20H25NO2.ClH/c1-21-13-12-20(16-6-4-3-5-7-16)17(14-21)15-23-19-10-8-18(22-2)9-11-19;/h3-11,17,20H,12-15H2,1-2H3;1H/t17-,20-;/m1./s1
CAS NO:56222-04-9
Molecular Formula:C20H26ClNO2
Molecular Weight :347.8789
Molecular Structure :
Flash Point: 142.6 °C
Enthalpy of Vaporization: 69.46 kJ/mol
Boiling Point: 437.9 °C at 760 mmHg
Vapour Pressure: 7.19E-08 mmHg at 25°C

Femoxetine hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 45mg/kg (45mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS		 European Journal of Pharmacology. Vol. 32, Pg. 108, 1975.
mouse LD50 oral 1408mg/kg (1408mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS		 European Journal of Pharmacology. Vol. 32, Pg. 108, 1975.
mouse LD50 subcutaneous 723mg/kg (723mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS		 European Journal of Pharmacology. Vol. 32, Pg. 108, 1975.
rat LD50 intravenous 48mg/kg (48mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS		 European Journal of Pharmacology. Vol. 32, Pg. 108, 1975.
rat LD50 oral 1473mg/kg (1473mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS		 European Journal of Pharmacology. Vol. 32, Pg. 108, 1975.
rat LD50 subcutaneous 1120mg/kg (1120mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS		 European Journal of Pharmacology. Vol. 32, Pg. 108, 1975.
women TDLo oral 2576mg/kg/23W (2576mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: NAUSEA OR VOMITING

LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"		 Acta Pharmacologica et Toxicologica. Vol. 58, Pg. 253, 1986.

Femoxetine hydrochloride Safety Profile

Human toxic effects by ingestion. Experimental reproductive effects. When Femoxetine hydrochloride (CAS NO.56222-04-9) is heated to decomposition ,it emits toxic fumes of NOx and HCl.

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