IUPAC Name: Sodium 2-(3-phenoxyphenyl)propanoate
Synonyms of Fenoprofen sodium (CAS NO.34691-31-1): D,l-2-(3-Phenoxyphenyl)propionic acid, sodium salt ; Propionic acid, 2-(3-phenoxyphenyl)-, sodium salt, (+-)-
InChI: InChI=1/C15H14O3.Na/c1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13;/h2-11H,1H3,(H,16,17);/q;+1/p-1
CAS NO: 34691-31-1
Molecular Formula: C15H13NaO3
Molecular Weight : 264.2517
Molecular Structure:
H bond acceptors: 3
H bond donors: 1
Freely Rotating Bonds: 4
Polar Surface Area: 46.53 Å2
Flash Point: 141.7 °C
Enthalpy of Vaporization: 66.41 kJ/mol
Boiling Point: 381.3 °C at 760 mmHg
Vapour Pressure: 1.71E-06 mmHg at 25°C
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD | intravenous | > 100mg/kg (100mg/kg) | Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 183, 1977. | |
dog | LD | oral | > 200mg/kg (200mg/kg) | Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 183, 1977. | |
mouse | LD50 | intraperitoneal | 286mg/kg (286mg/kg) | GASTROINTESTINAL: PERITONITIS | Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 4385, 1980. |
mouse | LD50 | intravenous | 471mg/kg (471mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: ATAXIA | Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 4385, 1980. |
mouse | LD50 | subcutaneous | 463mg/kg (463mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 4385, 1980. |
rat | LD50 | intraperitoneal | 234mg/kg (234mg/kg) | GASTROINTESTINAL: OTHER CHANGES | Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 4385, 1980. |
rat | LD50 | intravenous | 500mg/kg (500mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Toxicology and Applied Pharmacology. Vol. 25, Pg. 444, 1973. |
rat | LD50 | oral | 800mg/kg (800mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Toxicology and Applied Pharmacology. Vol. 25, Pg. 444, 1973. |
rat | LD50 | subcutaneous | 500mg/kg (500mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Toxicology and Applied Pharmacology. Vol. 25, Pg. 444, 1973. |
Poison by intraperitoneal route. Moderately toxic by ingestion, subcutaneous, and intravenous routes. When Fenoprofen sodium (CAS NO.34691-31-1) is heated to decomposition, it emits toxic fumes of Na2O. See also FENOPROFEN CALCIUM DIHYDRATE.
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View