IUPAC Name: 6,8-Dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione
Synonyms of Fervenulin (CAS NO.483-57-8) : 6,8-Dimethylpyrimido(5,4-e)-as-triazine-5,7(6H,8H)-dione ; Fervenulin Fervenuline ; Planomycin ; Pyrimido(5,4-e)-1,2,4-triazine-5,7(6H,8H)-dione, 6,8-dimethyl-
InChI: InChI=1/C7H7N5O2/c1-11-5-4(8-3-9-10-5)6(13)12(2)7(11)14/h3H,1-2H3
CAS NO:483-57-8
Molecular Formula:C7H7N5O2
Molecular Weight :193.1628
Molecular Structure :
Index of Refraction: 1.601
Surface Tension: 72.3 dyne/cm
Density: 1.474 g/cm3
Flash Point: 206.1 °C
Enthalpy of Vaporization: 67.05 kJ/mol
Boiling Point: 417.2 °C at 760 mmHg
Vapour Pressure: 3.61E-07 mmHg at 25°C
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
hamster | LD50 | intraperitoneal | 11200ug/kg (11.2mg/kg) | Antibiotics Annual. Vol. 7, Pg. 220, 1959/1960. | |
mouse | LD50 | intraperitoneal | 65mg/kg (65mg/kg) | Antibiotics Annual. Vol. 7, Pg. 220, 1959/1960. | |
mouse | LD50 | intravenous | 15mg/kg (15mg/kg) | "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 5, Pg. 199, 1981. | |
mouse | LD50 | unreported | 20mg/kg (20mg/kg) | "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967Vol. -, Pg. 518, 1967. |
Poison by intraperitoneal route. When Fervenulin (CAS NO.483-57-8) is heated to decomposition, it emits toxic fumes of NOx.
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