Product Name

  • Name

    Flomoxef sodium

  • EINECS 1308068-626-2
  • CAS No. 92823-03-5
  • Article Data4
  • CAS DataBase
  • Density 1.85g/cm3
  • Solubility
  • Melting Point
  • Formula C15H18 F2 N6 O7 S2 . Na
  • Boiling Point °Cat760mmHg
  • Molecular Weight 518.455
  • Flash Point °C
  • Transport Information
  • Appearance
  • Safety Moderately toxic by intravenous route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx, SOx, F−, and Cl−.
  • Risk Codes
  • Molecular Structure Molecular Structure of 92823-03-5 (Flomoxef sodium)
  • Hazard Symbols
  • Synonyms 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-,monosodium salt, (6R,7R)- (9CI); 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-,monosodium salt, (6R-cis)-; 6315 S Shionogi; 6315S; Flomoxef sodium; Flomoxefsodium salt; Flumarin
  • PSA 222.43000
  • LogP -2.29650

Flomoxef sodium Chemical Properties

Chemical Name: Flomoxef sodium
IUPAC NAME: (6R,7R)-7-[[2-(difluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; sodium
CAS No.: 92823-03-5
Molecular Formula: C15H17F2N6NaO7S2
Molecular Weight: 518.45 g/mol
Density: 1.85 g/cm3
Following is the structure of Flomoxef sodium (92823-03-5):


The chemical synonymous of Flomoxef sodium (92823-03-5) are 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-, monosodium salt, (6R,7R)- ; 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-, monosodium salt, (6R-cis)- ; 6315 S Shionogi ; 6315S ; Flomoxef sodium salt ; (6R,7R)-7-(2-((Difluoromethyl)thio)acetamido)-3-(((1-(2-hydroxyethyl)-1H-tetrazol-5-yl)thio)methyl)-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt ; Flomoxef sodium ; (6R,6β)-7α-[[[(Difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7β-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt

Flomoxef sodium Toxicity Data With Reference

1.    

ivn-rat LD50:7360 mg/kg

     NKRZAZ    Chemotherapy (Tokyo). 35 (Suppl 1)(1987),207.
2.    

scu-mus LD50:13,500 mg/kg

     IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 19 (1988),735.
3.    

ivn-mus LD50:7086 mg/kg

     IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 19 (1988),735.

Flomoxef sodium Safety Profile

Moderately toxic by intravenous route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx, SOx, F−, and Cl−.

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