-
Name
FUSARENON X
- EINECS
- CAS No. 23255-69-8
- Density 1.5g/cm3
- Solubility
- Melting Point 91-92℃
- Formula C17H22 O8
- Boiling Point 569.2°Cat760mmHg
- Molecular Weight 354.357
- Flash Point 208.4°C
- Transport Information
- Appearance
- Safety Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
- Risk Codes 11-20/21/22-36-36/37/38-28
-
Molecular Structure
- Hazard Symbols F,Xn,T+
- Synonyms Trichothec-9-en-8-one,12,13-epoxy-3a,4b,7a,15-tetrahydroxy-, 4-acetate (8CI); Spiro[2,5-methano-1-benzoxepin-10,2'-oxirane],trichothec-9-en-8-one deriv.; 3-Acetylnivalenol; 4-Acetylnivalenol; 4b-Acetoxy-3a,7a,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one;Fusarenon X; Fusarenone; Fusarenone X; NSC 197211; Nivalenol monoacetate
- PSA 125.82000
- LogP -1.29610
Fusarenon-X Chemical Properties
Empirical Formula of Fusarenon-X (CAS NO.23255-69-8): C17H22O8
Molecular Weight: 354.3518 g/mol
Index of Refraction: 1.615
Density: 1.5 g/cm3
Flash Point: 208.4 °C
Enthalpy of Vaporization: 98.1 kJ/mol
Boiling Point: 569.2 °C at 760 mmHg
Vapour Pressure: 2.51E-15 mmHg at 25 °C
Storage tempreture: -20 °C
Structure of Fusarenon-X (CAS NO.23255-69-8):
Fusarenon-X Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| cat | LDLo | subcutaneous | 1mg/kg (1mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING GASTROINTESTINAL: OTHER CHANGES LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" | Japanese Journal of Experimental Medicine. Vol. 41, Pg. 521, 1971. |
| dog | LDLo | intravenous | 900ug/kg (0.9mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING | Developments in Food Science. Vol. 4, Pg. 135, 1983. |
| duck | LD50 | subcutaneous | 2mg/kg (2mg/kg) | BEHAVIORAL: FLUID INTAKE GASTROINTESTINAL: NAUSEA OR VOMITING GASTROINTESTINAL: OTHER CHANGES | Japanese Journal of Experimental Medicine. Vol. 41, Pg. 521, 1971. |
| duck | LDLo | oral | 5mg/kg (5mg/kg) | BEHAVIORAL: FLUID INTAKE GASTROINTESTINAL: OTHER CHANGES GASTROINTESTINAL: NAUSEA OR VOMITING | Japanese Journal of Experimental Medicine. Vol. 41, Pg. 521, 1971. |
| guinea pig | LD50 | intraperitoneal | 500ug/kg (0.5mg/kg) | Developments in Food Science. Vol. 4, Pg. 135, 1983. | |
| guinea pig | LD50 | subcutaneous | 100ug/kg (0.1mg/kg) | Developments in Food Science. Vol. 4, Pg. 135, 1983. | |
| mouse | LD50 | intraperitoneal | 3300ug/kg (3.3mg/kg) | BEHAVIORAL: EXCITEMENT BLOOD: HEMORRHAGE | Pure and Applied Chemistry. Vol. 49, Pg. 1737, 1977. |
| mouse | LD50 | intravenous | 3400ug/kg (3.4mg/kg) | BEHAVIORAL: FOOD INTAKE (ANIMAL) BEHAVIORAL: FLUID INTAKE | Japanese Journal of Experimental Medicine. Vol. 41, Pg. 521, 1971. |
| mouse | LD50 | oral | 4500ug/kg (4.5mg/kg) | BEHAVIORAL: FOOD INTAKE (ANIMAL) BEHAVIORAL: FLUID INTAKE | Japanese Journal of Experimental Medicine. Vol. 41, Pg. 521, 1971. |
| mouse | LD50 | subcutaneous | 4200ug/kg (4.2mg/kg) | BEHAVIORAL: FOOD INTAKE (ANIMAL) BEHAVIORAL: FLUID INTAKE | Japanese Journal of Experimental Medicine. Vol. 41, Pg. 521, 1971. |
| mouse | LD50 | unreported | 7mg/kg (7mg/kg) | Japanese Journal of Experimental Medicine. Vol. 50, Pg. 167, 1980. | |
| rat | LD | intraperitoneal | > 4mg/kg (4mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | "Symposium on Mycotoxins in Human Health," Purchase, I.F.H., London, Macmillan, 1971Vol. -, Pg. 163, 1971. |
| rat | LD50 | oral | 4mg/kg (4mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: OTHER CHANGES | Japanese Journal of Experimental Medicine. Vol. 41, Pg. 521, 1971. |
| rat | LD50 | subcutaneous | 500ug/kg (0.5mg/kg) | Developments in Food Science. Vol. 4, Pg. 135, 1983. |
Fusarenon-X Consensus Reports
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 11 (1976),p. 169.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 31 (1983),p. 153.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
Fusarenon-X Safety Profile
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes of Fusarenon-X (CAS NO.23255-69-8): 
F,
Xn,
T+
Risk Statements: 11-20/21/22-36-36/37/38-28
R11:Highly flammable.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R28:Very toxic if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37-45-36/37/39-22
S22:Do not breathe dust.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37:Wear suitable protective clothing and gloves.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Fusarenon-X Specification
Fusarenon-X ,its cas register number is 23255-69-8. It also can be called Nivalenol monoacetate ; and Fusarenone X .
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