Product Name: Gestonorone caproate
CAS Registry Number: 1253-28-7
Synonyms: 17-((1-Oxohexyl)oxy)-19-norpregn-4-ene-3,20-dione ; 17-Hydroxy-19-norpregn-4-ene-3,20-dione hexanoate ; 17-alpha-Hexanoyloxy-19-nor-4-pregnene-3,20-dione ; 17-alpha-Hydroxy-19-norprogesterone caproate ; 17-beta-Acetyl-17-hydroxyestr-4-ene-3-one hexanoate ; 17alpha-Hydroxy-19-norprogesterone caproate ; 17alpha-Hydroxy-19-norprogesterone capronate ; 17alpha-Hydroxy-19norprogesterone-17alpha caproate ; 19-Nor-17alpha-hydroxyprogesterone caproate ; 19-Norpregn-4-ene-3,20-dione, 17-((1-oxohexyl)oxy)- ; 19-Norprogesterone, 17-hydroxy-, hexanoate ; CCRIS 6524 ; Caproate de gestonorone ; Caproate de gestonorone [INN-French] ; Caproato de gestonorona ; Caproato de gestonorona [INN-Spanish] ; Depostat ; EINECS 215-010-2 ; Gestonorone caproate ; Gestonorone capronate ; Gestonoroni caproas ; Gestonoroni caproas [INN-Latin] ; Gestronol caproate ; Gestronol hexanoate ; NSC 84054 ; Primostat ; SH 582 ; SH 80582 ; UNII-U38E620NS6 ; 9-Norpregn-4-ene-3,20-dione, 17-((1-oxohexyl)oxy)- ; 19-Norpregn-4-ene-3,20-dione, 17-hydroxy-, hexanoate ; Gestonorone caproate
IUPAC Name: [(8R,9S,10R,13S,14S,17R)-17-acetyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] hexanoate
Molecular Weight: 414.57752 [g/mol]
Molecular Formula: C26H38O4
XLogP3: 5.1
H-Bond Donor: 0
H-Bond Acceptor: 4
Surface Tension: 43.6 dyne/cm
Density: 1.11 g/cm3
Flash Point: 228.4 °C
Enthalpy of Vaporization: 81.19 kJ/mol
Boiling Point: 535.4 °C at 760 mmHg
Vapour Pressure: 1.54E-11 mmHg at 25°C
Following is the molecular structure of Gestonorone caproate (CAS NO.1253-28-7) is:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | intramuscular | > 150mg/kg (150mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982. | |
mouse | LD50 | intraperitoneal | > 10gm/kg (10000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LIVER: OTHER CHANGES BLOOD: CHANGES IN SPLEEN | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 296, 1977. |
mouse | LD50 | oral | > 10gm/kg (10000mg/kg) | LIVER: OTHER CHANGES | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 296, 1977. |
mouse | LD50 | subcutaneous | 10gm/kg (10000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982. | |
rat | LD50 | intramuscular | 400mg/kg (400mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 296, 1977. |
rat | LD50 | intraperitoneal | 6800mg/kg (6800mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982. | |
rat | LD50 | oral | > 10gm/kg (10000mg/kg) | GASTROINTESTINAL: OTHER CHANGES | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 296, 1977. |
rat | LD50 | subcutaneous | > 10gm/kg (10000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 296, 1977. |
Poison by intramuscular route. Experimental reproductive effects. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes.
Gestonorone caproate (CAS NO.1253-28-7) is a long-acting potent progestogen structurally related to PROGESTERONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1185)
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