Product Name

  • Name

    HEPTACHLOR

  • EINECS 200-962-3
    Annex I Index No: 602-046-00-2
  • CAS No. 76-44-8
  • Density 1.57
  • Solubility

    Stability

      Stable. Non-combustible. Incompatible with strong alkali, oxidizingagents. Corrodes many metals.

    Toxicology

      Toxic if inhaled, swallowed or absorbed through the skin.Readily absorbed through the
    • Melting Point 95 - 96 C
    • Formula C10H5 Cl7
    • Boiling Point decomposes
    • Molecular Weight 373.321
    • Flash Point 11oC
    • Transport Information
    • Appearance white crystalline solid
    • Safety Confirmed carcinogen with experimental carcinogenic data. A poison by ingestion, skin contact, intraperitoneal, and intravenous routes. Human mutation data reported. Acute exposure and chronic doses have caused liver damage. See also closely related chlordane. In humans, a dose of 1–3 g can cause serious symptoms, especially where liver impairment is the case. Acute symptoms include tremors, convulsions, kidney damage, respiratory collapse, and death. When heated to decomposition it emits toxic fumes of Cl.

      NOTE: The EPA has canceled registration of pesticides containing heptachlor with the exception of its use for termite control by subsurface ground insertion external to the dwelling.

    • Risk Codes 24/25-33-40-50/53-39/23/24/25-23/24/25-11-67-65-38-51/53
    • Molecular Structure Molecular Structure of 76-44-8 (HEPTACHLOR)
    • Hazard Symbols Toxic by ingestion, inhalation, and skin absorption; use has been restricted and discontinued except for termite control. TLV: 0.5 mg/m3; animal carcinogen.
    • Synonyms 4,7-Methanoindene,1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro- (8CI); 1,4,5,6,7,10,10-Heptachloro-4,7,8,9-tetrahydro-4,7-methyleneindene;1,4,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-methanoindene;1,4,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-endo-methanoindene;3-Chlorochlordene; Aahepta; Agroceres; Arbinex 30TN; E 3314; ENT 15,152; GPKh;Hepta; Heptachlor; Heptachlorane; Heptox; NSC 8930; Rhodiachlor; Velsicol 104
    • PSA 0.00000
    • LogP 5.24150
  • Heptachlor Chemical Properties

    CAS: 76-44-8
    EINECS: 200-962-3
    Product Categories: 2000/60/ECMore...Close... ; Alpha sort ; Baby Food Directives 13/2003 EC&14/2003 ECPesticides ; CyclodienesPesticides&Metabolites ; European Community: ISO and DIN;H;HA -HTMethod Specific ; H-MAlphabetic;Insecticides ; Method Specific ; Oeko-Tex Standard 100 ; PesticidesMethod Specific ; ASTM 4947: Analysis of Chlordane and Heptachlor in AirPesticides ; ASTM Air Monitoring ; 2000/60/EC ; Pesticides .
    Following is the Molecular Structure of Heptachlor (76-44-8):

    SMILES: ClC1/C=C\C2C3(Cl)C(\Cl)=C(\Cl)C(Cl)(C12)C3(Cl)Cl
    InChI: InChI=1/C10H5Cl7/c11-4-2-1-3-5(4)9(15)7(13)6(12)8(3,14)10(9,16)17/h1-5H
    InChIKey: FRCCEHPWNOQAEU-UHFFFAOYAM
    Std.InChI: InChI=1S/C10H5Cl7/c11-4-2-1-3-5(4)9(15)7(13)6(12)8(3,14)10(9,16)17/h1-5H
    Std.InChIKey: FRCCEHPWNOQAEU-UHFFFAOYSA-N
    Molecular Formula: C10H5Cl7
    Molecular Weight: 373.32
    Melting Point:
    Boiling Point: 392.3℃ at 760mmHg
    Flash Point: 192.9℃
    Molar Volume: 207.7cm3
    Density: 1.79g/cm3
    Index of Refraction: 1.645
    Molar Refractivity: 75.37cm3
    Surface Tension: 54.7dyne/cm
    Polarizability: 29.88 10-24cm3
    Enthalpy of Vaporization: 61.7kJ/mol
    Vapour Pressure: 5.23E-06mmHg at 25℃

    Heptachlor Uses

     Heptachlor (76-44-8) can be used as a insecticide.

    Heptachlor Toxicity Data With Reference

    Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
    cat LCLo inhalation 150mg/m3/4H (150mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 71, 1982.
    cat LDLo oral 50mg/kg (50mg/kg) BEHAVIORAL: EXCITEMENT

    BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

    BEHAVIORAL: AGGRESSION
    Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 2(5), Pg. 15, 1958.
    guinea pig LD50 oral 116mg/kg (116mg/kg)   Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 576, 1966.
    guinea pig LDLo skin 1gm/kg (1000mg/kg) BEHAVIORAL: EXCITEMENT

    BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

    BEHAVIORAL: AGGRESSION
    Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 2(5), Pg. 15, 1958.
    hamster LD50 oral 100mg/kg (100mg/kg)   European Journal of Toxicology and Environmental Hygiene. Vol. 7, Pg. 159, 1974.
    mammal (species unspecified) LCLo inhalation 200mg/m3/4H (200mg/m3) BEHAVIORAL: EXCITEMENT

    BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

    BEHAVIORAL: AGGRESSION
    Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 2(5), Pg. 15, 1958.
    mammal (species unspecified) LD50 unreported 60mg/kg (60mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 59, 1971.
    mouse LD50 intracrebral 12mg/kg (12mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Toxicology Letters. Vol. 60, Pg. 289, 1992.
    mouse LD50 intraperitoneal 130mg/kg (130mg/kg)   Soviet Genetics. English translation of GNKAA5. Vol. 2, Pg. 80, 1966.
    mouse LD50 oral 68mg/kg (68mg/kg)   Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 12, 1978.
    mouse LDLo intravenous 20mg/kg (20mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 107, Pg. 266, 1953.
    rabbit LD50 skin 500mg/kg (500mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 2(5), Pg. 15, 1958.
    rat LD50 intraperitoneal 27mg/kg (27mg/kg) BEHAVIORAL: TREMOR

    BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

    BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
    Food and Cosmetics Toxicology. Vol. 11, Pg. 63, 1973.
    rat LD50 oral 40mg/kg (40mg/kg)   Pharmaceutical Journal. Vol. 185, Pg. 361, 1960.
    rat LD50 skin 119mg/kg (119mg/kg)   Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 12, 1978.

    Heptachlor Consensus Reports

    IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man.7,1987,p.146.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man.20,1979,p.129.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210);Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man.5,1974,p.173.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A.,49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 20 , 1979,p. 129.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed) Clear Evidence: mouse NCITR*National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-9 ,1977. ; Results negative: rat NCITR*National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-9 ,1977. . EPA Genetic Toxicology Program. Community Right-To-Know List.

    Heptachlor Safety Profile

    Hazard Codes:  T Toxic,  N Dangerous for the environment,  F Flammable,  Xn Harmful.
    Risk Statements: 24/25-33-40-50/53-39/23/24/25-23/24/25-11-67-65-38
    R24/25: Toxic in contact with skin and if swallowed.
    R33: Danger of cumulative effects.
    R40: Limited evidence of a carcinogenic effect.
    R50/53: Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
    R39/23/24/25: Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed.
    R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
    R11: Highly Flammable.
    R67: Vapors may cause drowsiness and dizziness.
    R65: Harmful: May cause lung damage if swallowed.
    R38: Irritating to the skin.
    Safety Statements: 36/37-45-60-61-62-16-7
    S36/37: Wear suitable protective clothing and gloves.
    S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).
    S60: This material and/or its container must be disposed of as hazardous waste.
    S61: Avoid release to the environment. Refer to special instructions safety data sheet.
    S62: If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label.
    S16: Keep away from sources of ignition-No smoking.
    S7: Keep container tightly closed.
    RIDADR: 2761
    RTECS: PC0700000
    HazardClass: 6.1(a)
    PackingGroup: II
    Confirmed carcinogen with experimental carcinogenic data. A poison by ingestion, skin contact, intraperitoneal, and intravenous routes. Human mutation data reported. Acute exposure and chronic doses have caused liver damage. See also closely related chlordane. In humans, a dose of 1-3 g can cause serious symptoms, especially where liver impairment is the case. Acute symptoms include tremors, convulsions, kidney damage, respiratory collapse, and death.

    Heptachlor Standards and Recommendations

    OSHA PEL: TWA 0.5 mg/m3 (skin)
    ACGIH TLV: 0.05 mg/m3 (skin); Animal Carcinogen
    DFG MAK: 0.5 mg/m3, Confirmed Animal Carcinogen with Unknown Relevance to Humans.

    Heptachlor Specification

     Heptachlor (76-44-8) also called for Velsicol 104(r) ; E3314 ; E3314(r) ; Drinox(r) ; Cupincida ; Fennotox;(-)-heptachlor ; (+)-Heptachlor . Heptachlor (76-44-8) is a white to light tan waxy looking solid.It's noncombustible and insoluble in waterWhen heated to decomposition it emits toxic fumes of Cl−.It should be stored at 4℃.Be attention of this chemical is highly toxic.

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