Product Name

  • Name

    Hoechst 33342

  • EINECS 245-691-1
  • CAS No. 23491-52-3
  • Article Data3
  • CAS DataBase
  • Density 1.274±0.06 g/cm3(Predicted)
  • Solubility
  • Melting Point 268oC
  • Formula C27H28 N6 O
  • Boiling Point 725.9±70.0 °C(Predicted)
  • Molecular Weight 452.559
  • Flash Point
  • Transport Information
  • Appearance Yellow-green powder.
  • Safety Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.
  • Risk Codes 22-37/38
  • Molecular Structure Molecular Structure of 23491-52-3 (Hoechst 33342)
  • Hazard Symbols
  • Synonyms 2,5'-Bibenzimidazole,2'-(p-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)- (8CI); 2-[2-(4-Ethoxyphenyl)-6-benzimidazolyl]-6-(1-methyl-4-piperazinyl)benzimidazole;2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole;Bisbenzimide; HOE 33342; Ho 342; Hoechst 33342; NSC 334072
  • PSA 100.76000
  • LogP 7.13970

Hoechst 33342 Chemical Properties

IUPAC Name: 2-(4-Ethoxyphenyl)-6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazole
Molecular Formula: C27H28N6O.3(HCl).3(H2O)
Molecular Weight: 452.55g/mol
Freely Rotating Bonds: 5
Polar Surface Area: 73.07 Å2
Flash Point: 420.6 °C
Enthalpy of Vaporization: 114.34 kJ/mol
Boiling Point: 771.9 °C at 760 mmHg
Vapour Pressure: 3.19E-24 mmHg at 25°C 
The Cas Register Number of Bisbenzimide is 23491-52-3 .The chemical synonyms of Bisbenzimide (CAS NO. 23491-52-3) are 33258Hoechst ; 4-(5-(4-Methyl-1-piperazinyl)(2,5’-bi-1h-benzimidazol)-2’-yl)-phenotrihy ; 4-[5-(4-Methyl-1-piperazinyl)[2,5’-bi-1h-benzimidazol]-2’-yl]-phenotrihydr ; Bisbenzimidazoletrihydrochloride ; Bisbenzimidehydrochloride ; Hoe33058;Hoechstdye33258 ; Nsc-322921 .The molecular structure of Bisbenzimide (CAS NO. 23491-52-3) is.

Hoechst 33342 Uses

 It is an organic compound used as a fluorescent stain for DNA in molecular biology applications. It is an intercalating agent between Adenine-thymine base pairs.

Hoechst 33342 Toxicity Data With Reference

1.    

dni-hmn-hla 300 nmol/L

     CRNGDP    Carcinogenesis. 13 (1992),2389.
2.    

dnd-mus-fbr 5 µmol/L

     CRNGDP    Carcinogenesis. 9 (1988),485.
3.    

mnt-ham-ovr 10 µmol/L

     MUREAV    Mutation Research. 448 (2000),35.
4.    

dnd-ham-lng 1 µmol/L

     JHCYAS    Journal of Histochemistry and Cytochemistry. 30 (1982),111.
5.    

dni-ham-lng 1 µmol/L

     JHCYAS    Journal of Histochemistry and Cytochemistry. 30 (1982),111.

Hoechst 33342 Safety Profile

Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.
Hazard Codes:  HarmfulXn
Risk Statements: 22-36/38-36/37/38-20/21/22 
R22: Harmful if swallowed
R36/38:  Irritating to eyes and skin. .
R36/37/38: Irritating to eyes, respiratory system and skin.  
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36-24/25-23 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
S24/25: Avoid contact with skin and eyes 
S23: Do not breathe vapour. 
WGK Germany: 3
RTECS: SM1140500
F: 3-8-10

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