Toxici
Molecular Structure of Hycanthone mesylate (CAS NO. 23255-93-8):
IUPAC Name: Diethyl-[2-[[4-(hydroxymethyl)-9-oxothioxanthen-1-yl]amino]ethyl]azanium; methanesulfonate
Molecular Formula: C21H28N2O5S2
Molecular Weight: 452.587420 g/mol
H-Bond Donor: 3
H-Bond Acceptor: 6
Canonical SMILES: CC[NH+](CC)CCNC1=C2C(=C(C=C1)CO)SC3=CC=CC=C3C2=O.CS(=O)(=O)[O-]
InChI: InChI=1S/C20H24N2O2S.CH4O3S/c1-3-22(4-2)12-11-21-16-10-9-14(13-23)20-18(16)19(24)15-7-5-6-8-17(15)25-20;1-5(2,3)4/h5-10,21,23H,3-4,11-13H2,1-2H3;1H3,(H,2,3,4)
InChIKey: LOEQGPPJCCUXEJ-UHFFFAOYSA-N
Flash Point: 298.9 °C
Enthalpy of Vaporization: 90.02 kJ/mol
Boiling Point: 570.5 °C at 760 mmHg
Vapour Pressure: 7.42E-14 mmHg at 25 °C
Sensitive of Hycanthone mesylate (CAS NO. 23255-93-8): Light
1. | dnr-esc 16 µg/well | ENMUDM Environmental Mutagenesis. 3 (1981),429. | ||
2. | cyt-hmn:leu 1 µmol/L | MUREAV Mutation Research. 21 (1973),287. | ||
3. | cyt-hmn:lym 2400 µg/L | JTEHD6 Journal of Toxicology and Environmental Health. 1 (1976),211. | ||
4. | dni-hmn:lym 50 mg/L | BCPCA6 Biochemical Pharmacology. 22 (1973),1253. | ||
5. | sln-dmg-par 4400 µmol/L | MUREAV Mutation Research. 82 (1981),111. | ||
6. | sln-dmg-orl 4400 µmol/L | MUREAV Mutation Research. 82 (1981),111. | ||
7. | otr-rat-ipr 30 mg/kg | CNREA8 Cancer Research. 40 (1980),1157. | ||
8. | ipr-mus TDLo:815 mg/kg/33W-I:CAR | IJCNAW International Journal of Cancer. 23 (1979),97. | ||
9. | ims-hmn TDLo:3 mg/kg:CNS,GIT | PACHAS Pure and Applied Chemistry. 42 (1975),209. | ||
10. | ipr-rat LDLo:100 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 187 (1973),437. | ||
11. | orl-mus LD50:565 mg/kg |
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 13 , 1977,p. 91.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.
A poison by intraperitoneal, subcutaneous, intravenous, and intramuscular routes. Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Other experimental reproductive effects. Human systemic effects by intramuscular route: hallucinations, muscle weakness, nausea or vomiting. Human mutation data reported. When heated to decomposition it emits very toxic fumes of SOx. See also SULFONATES.
Hycanthone mesylate with cas registry number of 23255-93-8 is also called for AI3-61987 ; CCRIS 333 ; Etrenol ; HSDB 7094 ; Hycanthone methanesulfonate ; Hycanthone methanesulfonate (VAN) ; Hycanthone methanesulphonate ; Hycanthone monomethanesulfonate ; Hycanthone monomethanesulphonate ; 9H-Thioxanthen-9-one, 1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-, monomethanesulfonate (salt) ; N-(2-(Diethylamino)ethyl)-4-methoxy-9-oxoxanthene-1-amine monomethanesulphonate ; Thioxanthen-9-one, 1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-, monomethanesulfonate (salt) (8CI) . It is odorless yellow to yellow-orange powder with bitter taste.
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View