Product Name

  • Name

    HYDROQUINIDINE

  • EINECS 215-862-5
  • CAS No. 1435-55-8
  • Article Data31
  • CAS DataBase
  • Density 1.204 g/cm3
  • Solubility chloroform: 0.1 g/mL, clear
  • Melting Point 169-170 °C(lit.)
  • Formula C20H26N2O2
  • Boiling Point 498.365 °C at 760 mmHg
  • Molecular Weight 326.439
  • Flash Point 255.202 °C
  • Transport Information UN 1544
  • Appearance
  • Safety 36/37-36
  • Risk Codes 20/21/22
  • Molecular Structure Molecular Structure of 1435-55-8 (HYDROQUINIDINE)
  • Hazard Symbols HarmfulXn
  • Synonyms Hydroquinidine(6CI,7CI,8CI);(+)-Hydroquinidine;(9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol;10,11-Dihydroquinidine;Dihydroquinidine;
  • PSA 45.59000
  • LogP 3.33510

Hydroquinidine Chemical Properties

IUPAC Name: (S)-[(5R,7R)-5-Ethyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)
methanol
Product Name: Hydroquinidine
The MF of Hydroquinidine (CAS NO.1435-55-8) is C20H26N2O2.

                      
The MW of Hydroquinidine (CAS NO.1435-55-8) is 326.43.
Synonyms of Hydroquinidine (CAS NO.1435-55-8): (9s)-10,11-Dihydro-6’-methoxycinchonan-9-ol ; (9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol ; 10,11-Dihydroquinidine ; 11-Dihydro-6’-methoxy-1(9s)-cinchonan-9-O ; 6'-Methoxy-10,11-dihydrocinchonan-9-ol ; Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)- ; Hydroconchinine
Index of Refraction: 1.626 
EINECS: 215-862-5 
Density: 1.2 g/ml 
Flash Point: 255.2 °C
Boiling Point: 498.4 °C

Hydroquinidine Production

preparation products: hydroquinine (anthraquinone-1 4-diyl)-->hydroquinidine (anthraquinone-1,4-diyl) diether-->(dhqd)2pyr-->(dhqd)2phal

Hydroquinidine Toxicity Data With Reference

1.    

orl-rat LD50:369 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),589.
2.    

ivn-rat LD50:32 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),589.
3.    

ivn-mus LD50:56,500 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 84 (1945),184.

Hydroquinidine Safety Profile

A poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.Safety information of Hydroquinidine (CAS NO.1435-55-8):
Hazard Codes  HarmfulXn
Risk Statements 
20/21/22 Harmful by inhalation, in contact with skin and if swallowed
Safety Statements 
36/37 Wear suitable protective clothing and gloves
RIDADR  1544
WGK Germany  3
RTECS  MX3016000
HazardClass  6.1(b)
PackingGroup  III

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