Product Name

  • Name

    OPIPRAMOL DIHYDROCHLORIDE

  • EINECS
  • CAS No. 909-39-7
  • Density 1.129g/cm3
  • Solubility
  • Melting Point 210° (FR M209); mp 228-230° (DE 1133729)
  • Formula C23H29 N3 O . 2 Cl H
  • Boiling Point 555.1°Cat760mmHg
  • Molecular Weight 436.47
  • Flash Point 290.5°C
  • Transport Information
  • Appearance
  • Safety A poison by intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by ingestion: somnolence. When heated to decomposition it emits very toxic fumes of NOx and HCl.
  • Risk Codes 22-50/53
  • Molecular Structure Molecular Structure of 909-39-7 (OPIPRAMOL DIHYDROCHLORIDE)
  • Hazard Symbols
  • Synonyms 1-Piperazineethanol,4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-, dihydrochloride (7CI,8CI,9CI);5H-Dibenz[b,f]azepine, 1-piperazineethanol deriv.;4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol dihydrochloride;5-[g-(b-Hydroxyethylpiperazino)propyl]-5H-dibenzo[b,f]azepinedihydrochloride; Dinsidon; G 33040; Insidon; Insidone; Nisidana; Opipramolhydrochloride; Pramolan
  • PSA 29.95000
  • LogP 4.85330

Insidon dihydrochloride Chemical Properties

IUPAC Name: 2-[4-(3-Benzo[b][1]benzazepin-11-ylpropyl)piperazin-1-yl]ethanol dihydrochloride 
Synonyms of Insidon dihydrochloride (CAS NO.909-39-7) : 1-Piperazineethanol, 4-(3-(5H-dibenz(b,f)azepin-5-yl)propyl)-, dihydrochloride ; 4-(3-(5H-Dibenz(b,f)azepin-5-yl)propyl)-1-piperazineethanol dihydrochloride ; Insidon (TN) ; Opipramol dihydrochloride
Product Categories: Dopamine receptor
CAS NO:909-39-7
Molecular Formula:C23H31Cl2N3O        
Molecular Weight :436.41774     
Molecular Structure :
EINECS: 213-000-2
Flash Point: 290.5 °C 
Enthalpy of Vaporization: 88 kJ/mol 
Boiling Point: 555.1 °C at 760 mmHg 
Vapour Pressure: 3.72E-13 mmHg at 25°C 
Solubility : H2O: ~24 mg/mL
Appearance: Insidon dihydrochloride (CAS NO.909-39-7) is yellow solid.

Insidon dihydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo oral 36mg/kg/25D-C (36mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) American Journal of Psychiatry. Vol. 119, Pg. 465, 1962.
mouse LD50 intraperitoneal 120mg/kg (120mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964.
mouse LD50 intravenous 45mg/kg (45mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964.
mouse LD50 oral 443mg/kg (443mg/kg)   Rassegna di Studi Psichiatrici. Review of Psychiatric Studies. Vol. 52, Pg. 204, 1963.
mouse LD50 subcutaneous 315mg/kg (315mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964.
rabbit LD50 intravenous 11mg/kg (11mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964.
rat LD50 intraperitoneal 95mg/kg (95mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964.
rat LD50 intravenous 32mg/kg (32mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964.
rat LD50 oral 900mg/kg (900mg/kg)   Drugs in Japan Vol. 6, Pg. 161, 1982.
rat LD50 subcutaneous 497mg/kg (497mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964.

Insidon dihydrochloride Safety Profile

A poison by intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by ingestion: somnolence. When heated to decomposition it emits very toxic fumes of NOx and HCl.

Hazard CodesHarmfulXn,DangerousN
Risk Statements 22-50/53
R22:Harmful if swallowed. 
R50/53: Insidon dihydrochloride (CAS NO.909-39-7) is very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements 60-61
S60:This material and its container must be disposed of as hazardous waste. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
WGK Germany 3
RTECS TL9100000

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