Product Name

  • Name

    ISOFENPHOS

  • EINECS 246-814-1
  • CAS No. 25311-71-1
  • Article Data2
  • CAS DataBase
  • Density 1.157g/cm3
  • Solubility 18 mg l-1 (20 °C)
  • Melting Point -12℃
  • Formula C15H24 N O4 P S
  • Boiling Point 411.5°Cat760mmHg
  • Molecular Weight 345.4
  • Flash Point 202.7°C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion and skin contact. When heated to decomposition it emits toxic fumes of POx, SOx, and NOx.
  • Risk Codes 24/25-50/53
  • Molecular Structure Molecular Structure of 25311-71-1 (ISOFENPHOS)
  • Hazard Symbols
  • Synonyms Salicylic acid,isopropyl ester, O-ester with O-ethyl isopropylphosphoramidothioate (8CI);Phosphoramidothioic acid, isopropyl-, O-ethyl ester, O-ester with isopropylsalicylate (8CI);Amaze;BAY 92114;Bayer 92114;Isofenphos;Isophenphos;Oftanol;Pryfon 6;Pyfron 6;SRA 12869;
  • PSA 98.69000
  • LogP 4.93110

Isophenphos Chemical Properties

IUPAC: Propan-2-yl 2-[ethoxy-(propan-2-ylamino)phosphinothioyl]oxybenzoate
 Isophenphos with CAS NO. of 25311-71-1 is also called for 1-Methylethyl-2-((ethoxy((1-methylethyl)amino)phosphinothioyl)oxy) benzoate ; 2-((Ethoxy((1-methylethyl)amino)phosphinothioyl)oxy)benzoic acid 1-methylethyl ester ; 2-(O-Aethyl-N-isopropylamidothiophosphoryloxy)-benzosaeure-isopropylester ; 40 SD ; AI3-27748 ; Amaze ; BAY-92114 ; BAY-SRA-12869 ; BRN 2949615 ; Caswell No. 447AB ; Discus ; EINECS 246-814-1 ; EPA Pesticide Chemical Code 109401 ; HSDB 6983 ; Isopropyl O-(ethoxy(isopropylamino)phosphinothioyl)salicylate ; Isopropyl O-(ethoxy-N-isopropylamino(thiophosphoryl))salicylate ; Isopropyl salicylate O-ester with O-ethyl isopropylphosphoramidothioate (8CI) ; Isopropyl salicylate O-ester with O-ethylisopropylphosphoramidothioate ; Isopropyl salicylate ester of O-ethyl isopropylphosphoramidothioate ; LE-Mat ; O-Ethyl O-(2-isopropoxycarbonyl)phenyl isopropylphosphoramidothioate ; Oftanol ; Phosphoramidothioic acid, isopropyl-, O-ethyl O-(2-isopropoxycarbonylphenyl) ester ; Pyrfon ; SRA 128691 and so on.
CAS: 25311-71-1
Molecular Formula: C15H24NO4PS
Molecular Weight: 345.39
EINECS: 246-814-1
ACD/LogP: 4.12 
ACD/LogD (pH 5.5): 4.12 
ACD/LogD (pH 7.4): 4.12 
ACD/BCF (pH 5.5): 796.52 
ACD/BCF (pH 7.4): 796.53 
ACD/KOC (pH 5.5): 4152.21 
ACD/KOC (pH 7.4): 4152.22 
H bond acceptors: 5 
H bond donors: 1 
Freely Rotating Bonds: 8 
Index of Refraction: 1.528 
Molar Refractivity: 91.89 cm
Molar Volume: 298.3 cm3  
Surface Tension: 42.9 dyne/cm 
Density: 1.157 g/cm
Flash Point: 202.7°C 
Enthalpy of Vaporization: 66.4 kJ/mol 
Boiling Point: 411.5°C at 760 mmHg 
Vapour Pressure: 5.56E-07 mmHg at 25°C 
The appearance of  Isophenphos (CAS NO.25311-71-1) is colorless oil.
The molecular structure of  Isophenphos with CAS NO. of 25311-71-1:

Isophenphos Uses

 Isophenphos (CAS NO.25311-71-1) is used as insecticide.

Isophenphos Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 oral 3mg/kg (3mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: MUSCLE WEAKNESS

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Bulletin of Environmental Contamination and Toxicology. Vol. 33, Pg. 386, 1984.
mouse LD50 oral 91300ug/kg (91.3mg/kg)   "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976.
quail LD50 oral 13mg/kg (13mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Ecotoxicology and Environmental Safety. Vol. 8, Pg. 551, 1984.
rabbit LD50 skin 162mg/kg (162mg/kg)   Farm Chemicals Handbook. Vol. -, Pg. C173, 1991.
rat LC50 inhalation 144mg/m3/4H (144mg/m3)   "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A236, Pg. 1983,
rat LD50 oral 21100ug/kg (21.1mg/kg)   Experimental and Toxicologic Pathology. Vol. 51, Pg. 27, 1999.
rat LD50 skin 188mg/kg (188mg/kg)   Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 39, 1978.

Isophenphos Safety Profile

Poison by ingestion and skin contact. When heated to decomposition it emits toxic fumes of POx, SOx, and NOx.
Hazard Codes:  TToxic,N Dangerous
Risk Statements:  24/25-50/53
R24/25:Toxic in contact with skin and if swallowed.
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements:  36/37-45-60-61 
S36/37:Wear suitable protective clothing and gloves. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S60:This material and its container must be disposed of as hazardous waste. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: 3018
RTECS:  VO4395500
HazardClass:  6.1(a)
PackingGroup:  I

Isophenphos Specification

1.Removal in wastewater treatment of Isophenphos (CAS NO.25311-71-1) :
Total removal:35.83  percent
Total biodegradation:0.37  percent
Total sludge adsorption:5.46  percent
Total to air:0.00  percent
(using 10000 hr Bio P,A,S)
2.Reactivity Profile
 Isophenphos (CAS NO.25311-71-1) is susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides.

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