Product Name

  • Name

    L-DITHIOTHREITOL

  • EINECS 240-263-0
  • CAS No. 16096-97-2
  • Article Data14
  • CAS DataBase
  • Density 1.303 g/cm3
  • Solubility
  • Melting Point 51 °C
  • Formula C4H10O2S2
  • Boiling Point 364.453 °C at 760 mmHg
  • Molecular Weight 154.254
  • Flash Point 174.215 °C
  • Transport Information
  • Appearance white crystalline powder
  • Safety 26-36/37
  • Risk Codes 21/22-36/37/38
  • Molecular Structure Molecular Structure of 16096-97-2 (L-DITHIOTHREITOL)
  • Hazard Symbols HarmfulXn
  • Synonyms 2,3-Butanediol,1,4-dimercapto-, [R-(R*,R*)]- (9CI);Threitol, 1,4-dithio-, L- (8CI);(2R,3R)-1,4-Disulfanylbutane-2,3-diol;2,3-Butanediol, 1,4-dimercapto-, (2R,3R)-rel-;
  • PSA 118.06000
  • LogP -0.43220

L-Dithiothreitol Chemical Properties

Following is the structure of DTT (CAS NO.16096-97-2):

IUPAC NAME: (2R,3R)-1,4-Bis(sulfanyl)butane-2,3-diol
CAS No.: 16096-97-2
EINECS: 240-263-0
RTECS: EK1612000
Molecular Formula: C4H10O2S2
Molecular Weight: 154.25 g/mol
Melting Point: 51 °C
Density: 1.302 g/cm3 
Flash Point: 174.2 °C
Boiling Point: 364.5 °C at 760 mmHg
Product Categories: Biochemistry ; Chiral Building Blocks ; O-Substituted Sugars ; Simple Alcohols (Chiral) ; Sugar Alcohols ; Sugars ; Synthetic Organic Chemistry
The chemical synonymous of DTT (CAS NO.16096-97-2) are (R,R)-(-)-1,4-Dithio-l-threitoL ; 4-Dimercapto-3-butanediol-threo-1 ; (2R,3R)-Threo-1,4-dimercapto-2,3-butanediol ; (2R,3R)-(-)-2,3-Dihydroxy-1,4-butanedithiol ; (2R,3R)-(-)-1,4-Dimercapto-2,3-butanediol ; (-)-1,4-Dithio-l-threitol

L-Dithiothreitol Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 179mg/kg (179mg/kg)   Journal of Medicinal Chemistry. Vol. 15, Pg. 600, 1972.

L-Dithiothreitol Safety Profile

Hazard Codes of DTT (CAS NO.16096-97-2): HarmfulXn
Risk Statements: 21/22-36/37/38 
R21/22: Harmful in contact with skin and if swallowed. 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37: Wear suitable protective clothing and gloves.
WGK Germany: 3
RTECS: EK1612000
F: 10-13-23

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