L-Lactic dehydrogenase

EINECS: 232-617-8
Storage temp: 2-8°C
Form: Suspension
Color: White
Appearance: White lyophilized powder
Product categories of L-Lactic dehydrogenase (CAS NO.9001-60-9): Specialty Enzymes ; Oxidoreductases ; Enzyme Class Index ; 1.x.x.x Oxidoreductases ; 1.1.x.x Acting on hydroxyl groups  

  L-Lactic dehydrogenase (CAS NO.9001-60-9) has been used for biochemical studies, a test of pyruvate, and the infarction diagnosis of leukemia and myocardial.

With pigs' heart as raw material, has the treatment of Calcium phosphate gel and  fractionation of Ammonium sulfate, and then by dialysis, crystallization with Ammonium sulfate , at last, we get the product: L-Lactic dehydrogenase (CAS NO.9001-60-9).

Risk Statements:
21:  Harmful in contact with skin
22:  Harmful if swallowed 
36:  Irritating to the eyes
37:  Irritating to the respiratory system
38:  Irritating to the skin
Safety Statements:
22:  Do not breathe dust
24:  Avoid contact with skin
25:  Avoid contact with eyes
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing 
37:  Wear suitable gloves

 L-Lactic dehydrogenase (CAS NO.9001-60-9) also can be called L-Lactic acid dehydrogenase ; Dehydrogenase, lactate ; Lactic dehydrogenase .Crystalline enzyme activity of the same solution can be stored 6-8 weeks, and its sulfate suspension can be stable for more than a year.Its very dilute solution is unstable.And its optimum temperature is 39 ℃, then the temperature higher than 60 ℃, it will be rapid inactivation. Inhibitors, an excess amount of Pyruvate, excess NAD, Oxalic acid, Oxalic acid an amide, Hydroxy malonic acid, Malonic acid, Urea, Cu²⁺, Hg^{2 +_,}Ag ⁺, 4 - Chloro mercury benzoic acid, Pyrophosphate, or Phosphate buffer and in the alkaline from the Coenzyme I (NAD) to form a non-competitive inhibitors can inhibit the oxidation reaction, and excess Lactic acid and from the reduction of Coenzyme I (NADH) to form a non-competitive inhibitors can inhibit the reduction reaction; activator contains 2 - Amino--2 - methyl -1 - propanol, Fluoride, Diethanolamine, and Heparin (oxidation). Enzyme reaction: pyruvate + CoA reduction I + H + ═ lactate + coenzyme I.