WGK Germany | 3 |
RTECS | RR0404200 |
Molecular Structure:
Molecular Formula: C15H26N2O5
Molecular Weight: 314.3773
IUPAC Name: (2S,3S)-3-[[(2S)-4-Methyl-1-(3-methylbutylamino)-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
Synonyms of Loxistatin acid (CAS NO.76684-89-4): (+)-(2S,3S)-3-((S)-3-Methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxiranecarboxylic acid ; BRN 6688621 ; E 64C ; EP 475 ; EP 475 (Enzyme inhibitor) ; Oxiranecarboxylic acid, 3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)amino)carbonyl)-, (2S-(2-alpha,3-beta(R*)))- ; Oxiranecarboxylic acid, 3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)amino)carbonyl)-, (2S-(2alpha,3beta(R*)))-
CAS NO: 76684-89-4
Product Categories: Cysteine proteinase inhibitors ; Drug / Therapeutic Agent ; Enzyme Inhibitors ; Protease Inhibitors
Index of Refraction: 1.503
Molar Refractivity: 79.56 cm3
Molar Volume: 268.7 cm3
Surface Tension: 46.1 dyne/cm
Density: 1.169 g/cm3
Flash Point: 314.5 °C
Enthalpy of Vaporization: 97.05 kJ/mol
Boiling Point: 596.4 °C at 760 mmHg
Vapour Pressure of Loxistatin acid (CAS NO.76684-89-4): 9.14E-16 mmHg at 25°C
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 2400mg/kg (2400mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986. |
mouse | LD50 | intravenous | > 1gm/kg (1000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986. | |
rat | LD50 | intraperitoneal | 2140mg/kg (2140mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986. |
rat | LD50 | intravenous | > 1gm/kg (1000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 736, 1986. |
WGK Germany of Loxistatin acid (CAS NO.76684-89-4): 3
RTECS: RR0404200
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