-
Name
macbecin II
- EINECS
- CAS No. 73341-73-8
- Article Data2
- CAS DataBase
- Density 1.19g/cm3
- Solubility
- Melting Point
- Formula C30H44 N2 O8
- Boiling Point 698.9°C at 760 mmHg
- Molecular Weight 560.688
- Flash Point 376.5°C
- Transport Information
- Appearance
- Safety Poison by intraperitoneal route. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms 2-Azabicyclo[16.3.1]docosane,geldanamycin deriv.; Macbecin II; NSC 330500
- PSA 149.57000
- LogP 5.81680
Macbecin ii Chemical Properties
Molecular Structure of Macbecin ii (CAS NO.73341-73-8):
.png)
IUPAC Name: [(2R,3S,5R,6S,7R,8E,11S,12Z,14E)-20,22-dihydroxy-2,5,6-trimethoxy-3,7,9,11,15-pentamethyl-16-oxo-17-azabicyclo[16.3.1]docosa-1(22),8,12,14,18,20-hexaen-10-yl] carbamate
Empirical Formula: C30H44N2O8
Molecular Weight: 560.679
Surface Tension: 51.8 dyne/cm
Density: 1.19 g/cm3
Flash Point: 376.5 °C
Enthalpy of Vaporization: 105.99 kJ/mol
Boiling Point: 698.9 °C at 760 mmHg
Vapour Pressure: 3.5E-20 mmHg at 25°C
Index of Refraction: 1.565
Classification Code : Drug / Therapeutic Agent ; Mutation data ; Natural Product
Synonyms of Macbecin ii (CAS NO.73341-73-8): 2-Azabicyclo[16.3.1]docosa-1(22),4,6,10,18,20-hexaen-3-one, 9-[(aminocarbonyl)oxy]-20,22-dihydroxy-13,14,17-trimethoxy-4,8,10,12,16-pentamethyl- ; C-14919 E-2 ; NSC-330500
Macbecin ii Toxicity Data With Reference
| 1. | dnd-mus:leu 60 µmol/L | PAACA3 Proceedings of the American Association for Cancer Research. 24 (1983),321. | ||
| 2. | dni-mus:leu 100 nmol/L | PAACA3 Proceedings of the American Association for Cancer Research. 24 (1983),321. | ||
| 3. | oms-mus:leu 10 µmol/L | PAACA3 Proceedings of the American Association for Cancer Research. 24 (1983),321. | ||
| 4. | ipr-mus LD50:25 mg/kg | JANTAJ Journal of Antibiotics. 33 (1980),205. |
Macbecin ii Safety Profile
Poison by intraperitoneal route. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View