Mannomustine supplier | CasNO.576-68-1

Name
mannomustine
EINECS
CAS No. 576-68-1
Density 1.353g/cm³
Solubility
Melting Point 278°C (rough estimate)
Formula C10H22 Cl2 N2 O4
Boiling Point 541.9°C at 760 mmHg
Molecular Weight 305.202
Flash Point 281.5°C
Transport Information
Appearance
Safety Poison by intraperitoneal and intravenous routes. Human mutation data reported. An antineoplastic agent. When heated to decomposition it emits very toxic fumes of Cl⁻ and NO_x.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms Mannitol,1,6-bis[(2-chloroethyl)amino]-1,6-dideoxy-, D- (8CI);1,6-Bis(chloroethylaino)-1,6-bis-deoxy-D-mannitol; BCM; BCM (cytostatic);Mannitol mustard; Mannomustin; Mannomustine
PSA 104.98000
LogP -1.13140

Mannomustine Chemical Properties

Empirical Formula of Mannomustine (CAS NO.576-68-1): C₁₀H₂₂Cl₂N₂O₄
Molecular Weight: 305.1987 g/mol
EINECS: 209-404-3
Index of Refraction: 1.544
Density: 1.353 g/cm³
Flash Point: 281.5 °C
Enthalpy of Vaporization: 94.28 kJ/mol
Boiling Point: 541.9 °C at 760 mmHg
Vapour Pressure: 5.27E-14 mmHg at 25 °C
Structure of Mannomustine (CAS NO.576-68-1):

IUPAC Name: (2R,3R,4R,5R)-1,6-Bis(2-chloroethylamino)hexane-2,3,4,5-tetrol
Canonical SMILES: C(CCl)NCC(C(C(C(CNCCCl)O)O)O)O
Isomeric SMILES: C(CCl)NC[C@H]([C@H]([C@@H]([C@@H](CNCCCl)O)O)O)O
InChI: InChI=1S/C10H22Cl2N2O4/c11-1-3-13-5-7(15)9(17)10(18)8(16)6-14-4-2-12/h7-10,13-18H,1-6H2/t7-,8-,9-,10-/m1/s1
InChIKey: MQXVYODZCMMZEM-ZYUZMQFOSA-N

Mannomustine Toxicity Data With Reference

1.	dni-hmn:lym 100 µmol/L	AGACBH Agents and Actions, A Swiss Journal of Pharmacology. 4 (1974),117.
2.	ipr-rat LD50:56 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 11 (1961),143.
3.	ivn-rat LD50:56 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 20 (1970),1467.
4.	ivn-mus LD50:90 mg/kg	ANYAA9 Annals of the New York Academy of Sciences. 68 (1958),879.
5.	ivn-dog LD50:50 mg/kg	ANYAA9 Annals of the New York Academy of Sciences. 68 (1958),879.
6.	ivn-rbt LD50:50 mg/kg	ANYAA9 Annals of the New York Academy of Sciences. 68 (1958),879.
7.	ivn-gpg LDLo:20 mg/kg	ANYAA9 Annals of the New York Academy of Sciences. 68 (1958),879.

Mannomustine Safety Profile

Poison by intraperitoneal and intravenous routes. Human mutation data reported. An antineoplastic agent. When heated to decomposition Mannomustine (CAS NO.576-68-1) emits very toxic fumes of Cl⁻ and NO_x.

Mannomustine Specification

Mannomustine , its cas register number is 576-68-1. It also can be called Mannitol nitrogen mustard ; and 1,6-Bis((2-chloroethyl)amino)-1,6-dideoxy-D-mannitol .

Product Name

mannomustine

Mannomustine Chemical Properties

Mannomustine Toxicity Data With Reference

Mannomustine Safety Profile

Mannomustine Specification

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