-
Name
Mephenoxalone
- EINECS 200-723-3
- CAS No. 70-07-5
- Article Data52
- CAS DataBase
- Density 1.201g/cm3
- Solubility
- Melting Point 143-145°
- Formula C11H13 N O4
- Boiling Point 440°C at 760 mmHg
- Molecular Weight 223.229
- Flash Point 219.9°C
- Transport Information
- Appearance
- Safety Moderately toxic by ingestion and intraperitoneal routes. A tranquilizer. When heated to decomposition it emits toxic fumes of NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms 2-Oxazolidinone,5-[(o-methoxyphenoxy)methyl]- (6CI,7CI,8CI); (?à)-Mephenoxalone; 5-(o-Methoxyphenoxymethyl)-2-oxazolidinone;5-(o-Methoxyphenoxymethyl)-2-oxazolidone; AHR 233; Control-OM; Dorsiflex;Dorsilon; Ekilan; Lenetran; Lenetran Tab; Lenetranat; Mephenoxalone;Methoxadone; Methoxydon; Methoxydone; Metoxadon; Metoxadone; Moderamin; OM-518;Placidex; Riself; Tranpoise; Trepidone; Valans; Xerene
- PSA 56.79000
- LogP 1.51120
Mephenoxalone Chemical Properties
Product Name: 5-(o-Methoxyphenoxymethyl)-2-oxazolidone (CAS NO.70-07-5)
Molecular Formula: C11H13NO4
Molecular Weight: 223.22g/mol
Mol File: 70-07-5.mol
Einecs: 200-723-3
Boiling point: 440 °C at 760 mmHg
Flash Point: 219.9 °C
Density: 1.201 g/cm3
Surface Tension: 39.2 dyne/cm
Enthalpy of Vaporization: 69.71 kJ/mol
Vapour Pressure: 6.09E-08 mmHg at 25°C
XLogP3-AA: 1.4
H-Bond Donor: 1
H-Bond Acceptor: 4
Mephenoxalone Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 800mg/kg (800mg/kg) | Revista de la Asociacion Medica Argentina. Vol. 74, Pg. 82, 1960. | |
| mouse | LD50 | oral | > 5gm/kg (5000mg/kg) | Proceedings of the European Society for the Study of Drug Toxicity. Vol. 11, Pg. 212, 1970. | |
| rat | LD | intraperitoneal | > 1gm/kg (1000mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 134, Pg. 198, 1961. | |
| rat | LD50 | oral | 3820mg/kg (3820mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Toxicology and Applied Pharmacology. Vol. 6, Pg. 642, 1964. |
Mephenoxalone Safety Profile
Moderately toxic by ingestion and intraperitoneal routes. A tranquilizer. When heated to decomposition it emits toxic fumes of NOx.
Mephenoxalone Specification
5-(o-Methoxyphenoxymethyl)-2-oxazolidone ,its CAS NO. is 70-07-5,the synonyms is Mephenoxalone ; 5-[(2-Methoxyphenoxy)methyl]-2-oxazolidinone .
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