Product Name

  • Name

    Norinyl

  • EINECS
  • CAS No. 8015-29-0
  • Density
  • Solubility
  • Melting Point
  • Formula C21H26O2.C20H26O2
  • Boiling Point 442.3oC at 760 mmHg
  • Molecular Weight 608.858
  • Flash Point 190.8oC
  • Transport Information
  • Appearance
  • Safety Human systemic effects by ingestion: thrombocytopenia (decrease in the number of blood platelets), dyspnea, nausea or vomiting, fever. Human teratogenic and reproductive effects by ingestion: developmental abnormalities of the urogenital system; spermatogenesis; impotence; breast development in males; changes in the uterus, cervix, or vagina; female fertility effects. Experimental reproductive effects. Questionable human carcinogen producing liver tumors.
  • Risk Codes
  • Molecular Structure Molecular Structure of 8015-29-0 (Norinyl)
  • Hazard Symbols
  • Synonyms Norinyl
  • PSA 66.76000
  • LogP 7.40810

Mestranol mixture with Norethindrone Chemical Properties

IUPAC Name: (8R,9S,10R,13S,14S,17R)-17-Ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one ; (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol  
Following is the structure of Mestranol mixture with Norethindrone (CAS NO.8015-29-0):
                 
Empirical Formula: C41H52O4
Molecular Weight: 608.8492 g/mol
Flash Point: 190.8 °C
Enthalpy of Vaporization: 73.75 kJ/mol
Boiling Point of Mestranol mixture with Norethindrone (CAS NO.8015-29-0): 442.3 °C at 760 mmHg
Vapour Pressure of Mestranol mixture with Norethindrone (CAS NO.8015-29-0): 1.33E-08 mmHg at 25 °C
Canonical SMILES: CC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34.CC12CCC3C(C1CCC2(C#C)O)CCC4=C3C=CC(=C4)OC
Isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34.C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3C=CC(=C4)OC
InChI: InChI=1S/C21H26O2.C20H26O2/c1-4-21(22)12-10-19-18-7-5-14-13-15(23-3)6-8-16(14)17(18)9-11-20(19,21)2;1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,6,8,13,17-19,22H,5,7,9-12H2,2-3H3;1,12,15-18,22H,4-11H2,2H3/t17-,18-,19+,20+,21+;15-,16+,17+,18-,19-,20-/m10/s1
InChIKey: HFFGOURGAIOQBU-FOWHCLFSSA-N

Mestranol mixture with Norethindrone Toxicity Data With Reference

1.    

orl-wmn TDLo:26,460 µg/kg/5Y-I:CAR,LIV

    LANCAO    Lancet. 1 (1980),310.
2.    

orl-wmn TDLo:40 mg/kg/4Y-I:NEO,LIV

    JAMAAP    JAMA, Journal of the American Medical Association. 235 (1976),730.
3.    

orl-wmn TD:71 mg/kg/7Y-I:NEO,LIV

    ANSUA5    Annals of Surgery. 183 (1976),239.
4.    

orl-wmn TD:53 mg/kg/7Y-I:CAR,LIV,BLD

    LANCAO    Lancet. 1 (1980),365.
5.    

orl-wmn TDLo:10 mg/kg/Y-I:PUL,GIT,MET

    LANCAO    Lancet. 1 (1973),1479.

Mestranol mixture with Norethindrone Safety Profile

Human systemic effects by ingestion: thrombocytopenia (decrease in the number of blood platelets), dyspnea, nausea or vomiting, fever. Human teratogenic and reproductive effects by ingestion: developmental abnormalities of the urogenital system; spermatogenesis; impotence; breast development in males; changes in the uterus, cervix, or vagina; female fertility effects. Experimental reproductive effects. Questionable human carcinogen producing liver tumors.

Mestranol mixture with Norethindrone Specification

 Mestranol mixture with Norethindrone , its cas register number is 8015-29-0. It also can be called 17-alpha-Ethynyl-17-hydroxyestren-3-one and ethynylestradiol 3-methyl ether ; Conlumin ; Conlunett ; Conluten ; Ethynylestradiol 3-methyl ether and 17-alpha-ethynyl-17-hydroxyestren-3-one ; Ethynylestradiol methyl ether and norethindrone ; Mestranol mixed with norethisterone ; Norethindrone - mestranol mixture ; Norethindrone and ethynylestradiol methyl ether ; Norethindrone and mestranol ; Norethindrone-mestranol ; Norethindrone-mestranol mixture ; Noriday ; and Norinyl . Its classification code are Contraceptive Agents; Contraceptive Agents, Female; Contraceptives, Oral; Contraceptives, Oral, Combined; Drug / Therapeutic Agent; Hormone; Human Data; Reproductive Control Agents; Reproductive Effect; and Tumor data.

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