-
Name
Metalol
- EINECS
- CAS No. 955-48-6
- Density g/cm3
- Solubility
- Melting Point
- Formula C11H18 N2 O3 S . Cl H
- Boiling Point 433.1°Cat760mmHg
- Molecular Weight 294.83
- Flash Point 215.7°C
- Transport Information
- Appearance
- Safety Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl. See also SULFONATES.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms Methanesulfonamide,N-[4-[1-hydroxy-2-(methylamino)propyl]phenyl]-, monohydrochloride (9CI);Methanesulfonanilide, 4'-[1-hydroxy-2-(methylamino)propyl]-, hydrochloride(7CI); Methanesulfonanilide, 4'-[1-hydroxy-2-(methylamino)propyl]-,monohydrochloride (8CI);4'-[1-Hydroxy-2-(methylamino)propyl]methanesulfonanilide hydrochloride; Metalolhydrochloride; N-[p-(2-Methylamino-1-hydroxypropyl)phenyl]methanesulfonamidehydrochloride
- PSA 86.81000
- LogP 3.04610
Metalol hydrochloride Chemical Properties
Molecular structure of Metalol hydrochloride (CAS NO.955-48-6) is:
Product Name: Metalol hydrochloride
CAS Registry Number: 955-48-6
IUPAC Name: N-[4-[1-hydroxy-2-(methylamino)propyl]phenyl]methanesulfonamide hydrochloride
Molecular Weight: 294.79816 [g/mol]
Molecular Formula: C11H19ClN2O3S
H-Bond Donor: 4
H-Bond Acceptor: 5
Flash Point: 215.7 °C
Enthalpy of Vaporization: 72.63 kJ/mol
Boiling Point: 433.1 °C at 760 mmHg
Vapour Pressure: 2.86E-08 mmHg at 25°C
Classification Code: Anti-adrenergic [beta-receptor]
Metalol hydrochloride Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | intraperitoneal | 485mg/kg (485mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA | Journal of Pharmacology and Experimental Therapeutics. Vol. 149, Pg. 161, 1965. |
| mouse | LD50 | intraperitoneal | 785mg/kg (785mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA | Journal of Pharmacology and Experimental Therapeutics. Vol. 149, Pg. 161, 1965. |
| mouse | LD50 | oral | > 6gm/kg (6000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ATAXIA BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 149, Pg. 161, 1965. |
| rabbit | LD50 | oral | 1250mg/kg (1250mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA | Journal of Pharmacology and Experimental Therapeutics. Vol. 149, Pg. 161, 1965. |
| rat | LD50 | intraperitoneal | 850mg/kg (850mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA | Journal of Pharmacology and Experimental Therapeutics. Vol. 149, Pg. 161, 1965. |
| rat | LD50 | oral | > 6gm/kg (6000mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Journal of Pharmacology and Experimental Therapeutics. Vol. 149, Pg. 161, 1965. |
Metalol hydrochloride Safety Profile
Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl. See also SULFONATES.
Metalol hydrochloride Specification
Metalol hydrochloride , its cas register number is 955-48-6. It also can be called 4'-(1-Hydroxy-2-(methylamino)propyl methanesulfonanilide monohydrochloride ; MJ 1998 ; Metalol HCl ; Metalol hydrochloride ; Methanesulfonamide, N-(4-(1-hydroxy-2-(methylamino)propyl)phenyl)-, monohydrochloride ; Methanesulfonamide, N-(4-(1-hydroxy-2-(methylamino)propyl)phenyl)-, monohydrochloride ; Methanesulfonanilide, 4'-(1-hydroxy-2-(methylamino)propyl)-, hydrochloride .
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