• Name

  Methyl (S)-(-)-lactate

• EINECS 248-704-9
• CAS No. 27871-49-4
• Article Data91
• CAS DataBase
• Density 1.085 g/cm³
• Solubility miscible with water and hydrolysis in water
• Melting Point - 66 °C
• Formula C₄H₈O₃
• Boiling Point 145.3 °C at 760 mmHg
• Molecular Weight 104.106
• Flash Point 47.1 °C
• Transport Information UN 3272 3/PG 3
• Appearance clear liquid
• Safety 24
• Risk Codes 10-36/37
• Molecular Structure
• Hazard Symbols Xi
• Synonyms Lacticacid, methyl ester, L- (8CI);Propanoic acid, 2-hydroxy-, methyl ester, (S)-;(-)-Lactic acid methyl ester;(-)-Methyl 2-hydroxypropionate;(2S)-2-Hydroxypropanoicacid methyl ester;(S)-(-)-Lactic acid methyl ester;(S)-Methyl lactate;Methyl (2S)-2-hydroxypropanoate;Methyl L-lactate;
• PSA 46.53000
• LogP -0.45980

Synthetic route

547-64-8

methyl lactate

117-34-0

2,2-diphenylacetic acid

A

27871-49-4

(S)-Methyl lactate

B

17392-83-5

(R)-Methyl lactate

C

1208982-48-2

methyl (R)-2-(diphenylacetyloxy)propanoate

Conditions

Conditions	Yield
With (R)-(+)-2-phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole; 2,2-dimethylpropanoic anhydride; N-ethyl-N,N-diisopropylamine In diethyl ether at 20℃; for 12h; Inert atmosphere; Resolution of racemate; optical yield given as %ee; enantioselective reaction;	A n/a B n/a C 47%
With 2,2-dimethylpropanoic anhydride; N-ethyl-N,N-diisopropylamine; (R)-(+)-2-phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole In diethyl ether at 20℃; for 12h;	A n/a B n/a C 47%

...Expand

600-22-6

pyruvic acid methyl ester

A

27871-49-4

(S)-Methyl lactate

B

17392-83-5

(R)-Methyl lactate

Conditions

Conditions	Yield
With 2; hydrogen In methanol at 25℃; under 25857.4 Torr; for 4h; other keto esters; var. polystyrene-supported platinum and ruthenium catalysts; enantioselective hydrogenation;
With hydrogen; platinum on silica; Cinchonidin In dichloromethane at 24.9℃; under 7500.6 Torr; Product distribution; enantioselectivity, rate enhancement, var. of alkaloid, solvent, further with butane-2,3-dione;
With hydrogen; cinchonidine modified platinum at 19.9℃; under 7500.6 Torr; Rate constant; Product distribution; further alkaloid-modified platinum;

600-22-6

pyruvic acid methyl ester

27871-49-4

(S)-Methyl lactate

Conditions

Conditions	Yield
With hydrogen; Cinchonin In acetic acid at 25℃; under 7500.75 Torr; for 12h; enantioselective reaction;	99.8%

Methyl (S)-(-)-lactate Chemical Properties

Methyl (S)-(-)-lactate Safety Profile

Safety Information of METHYL S-(-)-LACTATE(27871-49-4):
Hazard Codes:Xi
Risk Statements:10-36/37
10:Flammable 
36/37:Irritating to eyes and respiratory system 
Safety Statements:24
24:Avoid contact with skin  
RIDADR:UN 3272 3/PG 3
WGK Germany:1
F:21
HazardClass:3
PackingGroup:III
HS Code:29181100

Methyl (S)-(-)-lactate Specification