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Tianjin Kind Pharma Co., Ltd.

Factory direct sales, accept customization. Methyl Pyruvate acts as a potent secretagogue used in the study of stimulus-secretion coupling. Also used in the preparation of quinoxalines as dual phoosphodiesterase 2/10 (PDE2/10) inhibitors. It increas

Methyl Pyruvate

Cas:600-22-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Jinon Pharma (Wuhan) Co., Ltd.

Product name: Methyl pyruvate CAS: 600-22-6 Molecular formula: C4H6O3 Chemical structure: Methyl pyruvate Notes: physical and chemical properties density 1.13 boiling point 134-137 ºC refractive index

Methyl pyruvate

Cas:600-22-6

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Methyl pyruvate Manufacturer/High quality/Best price/In stock

Cas:600-22-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Jinan Finer Chemical Co., Ltd

Product description: Product name Methyl pyruvate CAS number 600-22-6 Assay ≥98% Appearance Yellow transparent liquid Capacity 200mt/year Application Pharmaceutical/pesticide

Methyl pyruvate

Cas:600-22-6

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

Methyl pyruvate CAS 600-22-6 Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributin

Methyl pyruvate CAS 600-22-6

Cas:600-22-6

Min.Order:1 Kilogram

FOB Price: $50.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Methyl pyruvate

Cas:600-22-6

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Methyl pyruvate

Cas:600-22-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res

methyl pyruvate

Cas:600-22-6

Min.Order:1 Kilogram

FOB Price: $200.0 / 300.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--600-22-6--Methyl pyruvate in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business relationship

TIANFUCHEM--600-22-6--Methyl pyruvate in stock

Cas:600-22-6

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 600-22-6 with best price

Cas:600-22-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product name Methyl pyruvate CAS 600-22-6 Synonyms 2-oxo-propionicacidmethylester;Methylglyoxylic acid methyl ester;PYR ME;PYRUVIC ACID METHYL ESTER;PAME;2-OXOPROPANOIC ACID METH

Methyl pyruvate

Cas:600-22-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

1)quick response within 12 hours; 2)quality guarantee: all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. 3) oem/odm available; 4) rea

Methyl pyruvateCAS NO.:600-22-6

Cas:600-22-6

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Propanoic acid, 2-oxo-,methyl ester 600-22-6

Cas:600-22-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Methyl pyruvate CAS:600-22-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediat

Methyl pyruvate CAS:600-22-6

Cas:600-22-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Propanoic acid, 2-oxo-,methyl ester

Cas:600-22-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products with competi

Good supplier Methyl pyruvate with high purity

Cas:600-22-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Methyl pyruvate

Cas:600-22-6

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Methyl Pyruvate

Cas:600-22-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

Methyl pyruvate CAS 600-22-6

Cas:600-22-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Methyl pyruvate

Cas:600-22-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Methyl pyruvate

Cas:600-22-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

METHYL PYRUVATE

Cas:600-22-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Methyl pyruvate

Cas:600-22-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

Our Advantages Production: Advanced chemical equipment with years of experience.Staffs for producing various extract products. Quality Control:A complete set of Testing Professional and Analysis Equipment ensures the Quality Requirements and Speci

Methyl Pyruvate CAS NO.600-22-6

Cas:600-22-6

Min.Order:1 Kilogram

FOB Price: $150.0 / 180.0

Type:Trading Company

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

High quality Methyl pyruvate

Cas:600-22-6

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products Methyl pyruvate

Cas:600-22-6

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

Methyl pyruvate

Cas:600-22-6

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Methyl Pyruvate

Cas:600-22-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: Methyl Pyruvate CAS No.:600-22-6 Molecule Formula:C4H6O3 Molecule Weight:102.09 Purity: 98.0% Package: 25kg/drum Description:Colorless to yellowish transparent liquid Manufacture Standards:Enterprise Standard

Best Quality Methyl Pyruvate

Cas:600-22-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Synthetic route

methyl lactate
547-64-8

methyl lactate

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With hydrogenchloride; zinc(II) nitrate; hydroxylamine hydrochloride; oxygen; copper(II) nitrate; sodium hydroxide at 100℃; under 75.0075 Torr; for 8h; Molecular sieve; Autoclave; Green chemistry;98.9%
With p-methoxybenzenetellurinic acid anhydride In neat (no solvent) at 130℃; for 1h;90%
With hydrogenchloride; sodium hypobromide In dichloromethane; water at 25℃; for 5h;90%
methanol
67-56-1

methanol

2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 83℃; Temperature;76.38%
With ethanesulfonic acid; 1,2-dichloro-ethane
methacrylic acid methyl ester
80-62-6

methacrylic acid methyl ester

A

formaldehyd
50-00-0

formaldehyd

B

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With dihydrogen peroxide; acetic acid at 24.84℃; under 760.051 Torr; Kinetics; Mechanism; UV-irradiation;A n/a
B 76%
With ozone at 20.84℃; under 760 Torr; Kinetics; Darkness;A 55%
B 69%
benzofurazan oxide
480-96-6

benzofurazan oxide

methyl 2-(triphenylphosphoranylidene)propionate
2605-68-7

methyl 2-(triphenylphosphoranylidene)propionate

A

benzofurazan
273-09-6

benzofurazan

B

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
In benzene for 6h; Heating;A 45%
B n/a
methacrylic acid methyl ester
80-62-6

methacrylic acid methyl ester

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With dihydrogen peroxide; triethylamine; chromium(VI) oxide In acetonitrile at 40℃; for 20h; Product distribution; variation of catalyst, reagent, temperature, time;41%
With dihydrogen peroxide; triethylamine; chromium(VI) oxide In acetonitrile at 40℃; for 20h;41%
Stage #1: methacrylic acid methyl ester With cis-[Ru(2,9-Me2phen)2(OH2)2](PF6)2 In acetonitrile at 55℃; for 0.5h;
Stage #2: With dihydrogen peroxide In acetonitrile for 8h;
methanol
67-56-1

methanol

2-oxopropanal
78-98-8

2-oxopropanal

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With carbon dioxide; 1,3-bis[2,6-di(propan-2-yl)phenyl]-2-methoxyimidazolidine In tetrahydrofuran at 20℃; for 8h; Inert atmosphere; Sealed tube;10%
methanol
67-56-1

methanol

acrolein
107-02-8

acrolein

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With selenium(IV) oxide
Methyl 2-acetamidoacrylate
35356-70-8

Methyl 2-acetamidoacrylate

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With hydrogen bromide In chloroform
1,4-Bis-methoxycarbonyl-1,2,3,4-tetramethyl-butadien-1,3
91765-79-6

1,4-Bis-methoxycarbonyl-1,2,3,4-tetramethyl-butadien-1,3

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
(i) O3, MeOH, (ii) H2, Pd-C; Multistep reaction;
silver pyruvate
62163-16-0

silver pyruvate

methyl iodide
74-88-4

methyl iodide

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

methanol
67-56-1

methanol

2-chloro-3-methylbutadiene
1809-02-5

2-chloro-3-methylbutadiene

A

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

B

Dimethoxymethane
109-87-5

Dimethoxymethane

C

acetic acid methyl ester
79-20-9

acetic acid methyl ester

D

methyl 2,2-dimethoxypropionate
10076-48-9

methyl 2,2-dimethoxypropionate

E

methacrylic acid methyl ester
80-62-6

methacrylic acid methyl ester

F

2-Chlor-3,3-dimethoxy-1-buten
108365-85-1

2-Chlor-3,3-dimethoxy-1-buten

Conditions
ConditionsYield
With ozone at -78℃; Product distribution; mono- and diozonolysies; with and without work up with DMS;A n/a
B n/a
C 35 % Spectr.
D 47 % Spectr.
E 7 % Spectr.
F 93 % Spectr.
methanol
67-56-1

methanol

(2-Chlor-1-methoxy-1-methyl-2-propenyl)hydroperoxide
108365-81-7

(2-Chlor-1-methoxy-1-methyl-2-propenyl)hydroperoxide

A

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

B

Dimethoxymethane
109-87-5

Dimethoxymethane

C

acetic acid methyl ester
79-20-9

acetic acid methyl ester

D

methoxymethyl hydroperoxide
10027-72-2

methoxymethyl hydroperoxide

E

acetic acid
64-19-7

acetic acid

F

methyl α-hydroperoxy-α-methoxypropionate
108365-82-8

methyl α-hydroperoxy-α-methoxypropionate

Conditions
ConditionsYield
With ozone In 1,1,2,2-tetrachloroethylene at -50℃; Product distribution; ozonolysis;
Methyl 2-bromopropionate
5445-17-0

Methyl 2-bromopropionate

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With 4-(dimethylamino)pyridine N-oxide In acetonitrile for 0.333333h; Heating;90 % Chromat.
3-chloro-DL-alanine methyl ester
56410-68-5

3-chloro-DL-alanine methyl ester

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With H2O In water at 25℃; Rate constant; Thermodynamic data; Kinetics; E(act.), ΔH(act.), ΔS(act.); with or without pyridoxal methochloride;
methyl 2-methoxyacrylate
7001-18-5

methyl 2-methoxyacrylate

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With perchloric acid at 25℃; Rate constant;
C10H14O10
96204-70-5

C10H14O10

A

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

B

methyl lactate
547-64-8

methyl lactate

C

carbon dioxide
124-38-9

carbon dioxide

Conditions
ConditionsYield
In benzene at 55℃; Rate constant; Product distribution; oth. temperature. oth. solvent;
3-carbomethoxy-3-methyl-1,2,4-trioxolane
105949-86-8

3-carbomethoxy-3-methyl-1,2,4-trioxolane

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With dimethylsulfide In chloroform-d1 Yield given;
dimethylglyoxal
431-03-8

dimethylglyoxal

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With (η5-C5H4SiMe3)2NbH(O)C=CPh2 at 25℃;
methanol
67-56-1

methanol

methacrylic acid methyl ester
80-62-6

methacrylic acid methyl ester

A

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

B

methoxymethanol
4461-52-3

methoxymethanol

C

methoxymethyl hydroperoxide
10027-72-2

methoxymethyl hydroperoxide

D

3-carbomethoxy-3-methyl-1,2,4-trioxolane
105949-86-8

3-carbomethoxy-3-methyl-1,2,4-trioxolane

E

methyl α-hydroperoxy-α-methoxypropionate
108365-82-8

methyl α-hydroperoxy-α-methoxypropionate

Conditions
ConditionsYield
With ozone at -78℃; Product distribution; ozonolysis;
Oxalacetic acid
328-42-7

Oxalacetic acid

methyl iodide
74-88-4

methyl iodide

A

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

B

3-methyl-2-oxo-butane-1,4-dioic acid dimethyl ester
63921-06-2

3-methyl-2-oxo-butane-1,4-dioic acid dimethyl ester

Conditions
ConditionsYield
Yield given. Multistep reaction. Yields of byproduct given;
methanol
67-56-1

methanol

2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

A

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

B

methyl 2,2-dimethoxypropionate
10076-48-9

methyl 2,2-dimethoxypropionate

Conditions
ConditionsYield
With chloro-trimethyl-silane; 2,2-dimethoxy-propane for 24h; Ambient temperature;A 71 % Chromat.
B 29 % Chromat.
Methyl isobutyrate
547-63-7

Methyl isobutyrate

A

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

B

acetone
67-64-1

acetone

Conditions
ConditionsYield
With hydroxide at 23.85℃; under 760 Torr; Kinetics; Oxidation;
methyl iodide
74-88-4

methyl iodide

silver salt of/the/ pyruvic acid

silver salt of/the/ pyruvic acid

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

cis-form of γ-methyl-glutaconic acid dimethyl ester
53358-15-9

cis-form of γ-methyl-glutaconic acid dimethyl ester

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

methyl lactate
547-64-8

methyl lactate

air

air

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
in der Waerme am Licht;
methyl lactate
547-64-8

methyl lactate

oxygen

oxygen

vanadium pentoxide

vanadium pentoxide

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

propanoic acid methyl ester
554-12-1

propanoic acid methyl ester

A

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

B

Methyl glyoxylate
922-68-9

Methyl glyoxylate

C

Propionic formic anhydride
10500-31-9

Propionic formic anhydride

D

propionic acid
802294-64-0

propionic acid

Conditions
ConditionsYield
With air; Propanil at 22.85℃; under 740 Torr; Kinetics; Oxidation;A 0.289 mol
B 0.111 mol
C 0.099 mol
D 0.139 mol
methyl pyruvate oxime
5634-53-7

methyl pyruvate oxime

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With hydroxylamine In 1,4-dioxane; water at 30℃; pH=6.75; Equilibrium constant;
methacrylic acid methyl ester
80-62-6

methacrylic acid methyl ester

A

methyl 2-methyl-2-oxiranecarboxylate
58653-97-7

methyl 2-methyl-2-oxiranecarboxylate

B

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Conditions
ConditionsYield
With Nitrogen dioxide; ozone at 250℃; for 4.44444E-06h; gas phase;A 88 % Spectr.
B n/a
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

methyl lactate
547-64-8

methyl lactate

Conditions
ConditionsYield
With magnesium(II) perchlorate; polymer-bound NADH (2a) In acetonitrile; benzene at 80℃; for 120h; Further byproducts given;100%
With carbonylhydrido(tetrahydroborato)[bis(2-diphenylphosphinoethyl)-amino]ruthenium(II); hydrogen; sodium hydrogencarbonate In methanol at 25℃; under 7500.75 Torr; for 12h; Glovebox; Autoclave; chemoselective reaction;98%
With hydrogen; Et4N91%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

1-ethylthio-1-(trimethylsiloxy)ethene
63584-41-8

1-ethylthio-1-(trimethylsiloxy)ethene

(S)-ethyl 3-hydroxy-3-methoxycarbonylbutanethioate
127658-10-0

(S)-ethyl 3-hydroxy-3-methoxycarbonylbutanethioate

Conditions
ConditionsYield
With hydrogenchloride; (S,S)-Cu(II) complex from bis(oxazolinyl) ligand and Cu(OTf)2 In tetrahydrofuran at -78℃;100%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

(R)-Methyl lactate
17392-83-5

(R)-Methyl lactate

Conditions
ConditionsYield
With hydrogen; Cinchonidin; polyvinylpyrrolidone-stabilized platinum clusters In acetic acid at 25℃; under 30002.4 Torr; for 0.5h;100%
With hydrogen; butan-1-ol; PVP-Pt; Cinchonidin In acetic acid at 24.85℃; under 30002.4 Torr; for 0.5h;
Stage #1: bis(1,5-cyclooctadiene)rhodium(I) trifluoromethanesulfonate; (R)-N-diphenylphosphino-N-methyl-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine In tetrahydrofuran at 25℃; for 0.25h;
Stage #2: pyruvic acid methyl ester With hydrogen In tetrahydrofuran under 1277.21 - 1794.37 Torr; for 6h; Product distribution / selectivity;
n/a
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

4,4-bis(benzyloxycarbonyl)-1,7-dimethylhepta-1,6-diyne
507989-55-1

4,4-bis(benzyloxycarbonyl)-1,7-dimethylhepta-1,6-diyne

C29H30O7

C29H30O7

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In dichloromethane at 20℃; for 0.166667h;100%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

(2-chloro-5-methyl-phenyl)-hydrazine

(2-chloro-5-methyl-phenyl)-hydrazine

methyl pyruvate 2-chloro-5-methylphenylhydrazone
187607-97-2

methyl pyruvate 2-chloro-5-methylphenylhydrazone

Conditions
ConditionsYield
In benzene100%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

(S)-Methyl lactate
27871-49-4

(S)-Methyl lactate

Conditions
ConditionsYield
With hydrogen; Cinchonin In acetic acid at 25℃; under 7500.75 Torr; for 12h; enantioselective reaction;99.8%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

2-methoxy-4-nitrophenylhydrazine
41978-94-3

2-methoxy-4-nitrophenylhydrazine

(E)-2-[(2-methoxy-4-nitrophenyl)hydrazono]propionic acid methyl ester

(E)-2-[(2-methoxy-4-nitrophenyl)hydrazono]propionic acid methyl ester

Conditions
ConditionsYield
With sodium acetate In methanol at 20℃; for 18h;99%
1-methylindole
603-76-9

1-methylindole

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

methyl 2,2-bis(1-methyl-1H-indol-3-yl)propanoate

methyl 2,2-bis(1-methyl-1H-indol-3-yl)propanoate

Conditions
ConditionsYield
With (S)-[1,1']-binaphthalenyl-2,2'-diol; titanium(IV) isopropylate In diethyl ether; toluene at -20℃; for 60h; Friedel-Crafts reaction;99%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

2-(1-allyl-2-oxoindolin-3-ylidene)malononitrile
519168-62-8

2-(1-allyl-2-oxoindolin-3-ylidene)malononitrile

(R)-methyl 1-allyl-2'-amino-3'-cyano-2-oxospiro[indoline-3,4'-pyran]-6'-carboxylate
1370462-66-0

(R)-methyl 1-allyl-2'-amino-3'-cyano-2-oxospiro[indoline-3,4'-pyran]-6'-carboxylate

Conditions
ConditionsYield
With 1-(((1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)methyl)-3-((1R)-(6-methoxyquinolin-4-yl)(8-vinylquinuclidin-2-yl)-methyl)thiourea In diethyl ether at 20℃; for 0.5h; asymmetric Michael cyclization; Molecular sieve; Inert atmosphere; optical yield given as %ee; enantioselective reaction;99%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

2-(2-oxo-1-phenylindolin-3-ylidene)malononitrile
1370462-98-8

2-(2-oxo-1-phenylindolin-3-ylidene)malononitrile

(R)-methyl 2'-amino-3'-cyano-2-oxo-1-phenylspiro[indoline-3,4'-pyran]-6'-carboxylate
1370462-64-8

(R)-methyl 2'-amino-3'-cyano-2-oxo-1-phenylspiro[indoline-3,4'-pyran]-6'-carboxylate

Conditions
ConditionsYield
With 1-(((1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)methyl)-3-((1R)-(6-methoxyquinolin-4-yl)(8-vinylquinuclidin-2-yl)-methyl)thiourea In diethyl ether at 20℃; for 3h; asymmetric Michael cyclization; Molecular sieve; Inert atmosphere; optical yield given as %ee; enantioselective reaction;99%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

2-oxo-2,3-dihydroindolylidenemalononitrile
6623-89-8

2-oxo-2,3-dihydroindolylidenemalononitrile

(R)-methyl 2'-amino-3'-cyano-2-oxospiro[indoline-3,4'-pyran]-6'-carboxylate
1370462-61-5

(R)-methyl 2'-amino-3'-cyano-2-oxospiro[indoline-3,4'-pyran]-6'-carboxylate

Conditions
ConditionsYield
With 1-(((1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)methyl)-3-((1R)-(6-methoxyquinolin-4-yl)(8-vinylquinuclidin-2-yl)-methyl)thiourea In diethyl ether at 20℃; for 12h; asymmetric Michael cyclization; Molecular sieve; Inert atmosphere; optical yield given as %ee; enantioselective reaction;99%
2-Aminonicotinaldehyde
7521-41-7

2-Aminonicotinaldehyde

pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

1,8-naphthyridine-2-carboxylic acid
215523-34-5

1,8-naphthyridine-2-carboxylic acid

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water at 20℃; for 16h; Cooling;99%
With water; sodium hydroxide In ethanol at 0 - 20℃; for 18h;
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

Benzoic acid (2S,3R,4R,4aS,10aR)-3-acetylamino-2-benzyloxy-6,6,8,8-tetraisopropyl-hexahydro-1,5,7,9-tetraoxa-6,8-disila-benzocycloocten-4-yl ester
145259-91-2

Benzoic acid (2S,3R,4R,4aS,10aR)-3-acetylamino-2-benzyloxy-6,6,8,8-tetraisopropyl-hexahydro-1,5,7,9-tetraoxa-6,8-disila-benzocycloocten-4-yl ester

Benzyl 2-acetamido-3-O-benzoyl-2-deoxy-4,6-O-<1-(methoxycarbonyl)ethylidene>-α-D-glucopyranoside
143836-21-9

Benzyl 2-acetamido-3-O-benzoyl-2-deoxy-4,6-O-<1-(methoxycarbonyl)ethylidene>-α-D-glucopyranoside

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate In dichloromethane for 15h; Ambient temperature;98%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

aniline
62-53-3

aniline

methyl 2-methyl-5-oxo-1-phenyl-4-(phenylamino)-2,5-dihydro-1H-pyrrole-2-carboxylate
26458-36-6

methyl 2-methyl-5-oxo-1-phenyl-4-(phenylamino)-2,5-dihydro-1H-pyrrole-2-carboxylate

Conditions
ConditionsYield
In dichloromethane at 20 - 25℃; for 1h; Irradiation;98%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

[1-(4-methoxyphenyl)vinyloxy]trimethylsilane
55991-65-6

[1-(4-methoxyphenyl)vinyloxy]trimethylsilane

(R)-methyl 2-hydroxy-2-methyl-4-oxo-4-(4-methoxy-phenyl)butanoate
1010691-58-3

(R)-methyl 2-hydroxy-2-methyl-4-oxo-4-(4-methoxy-phenyl)butanoate

Conditions
ConditionsYield
With (S)-N-[2-[(4S,5R)-4-methyl-5-phenyl-4,5-dihydro-2-oxazolyl]phenyl]-S-methyl-S-phenylsulfoximine; copper(II) bis(trifluoromethanesulfonate) In 2,2,2-trifluoroethanol; toluene at -20℃; for 16h; Mukaiyama reaction; optical yield given as %ee; enantioselective reaction;98%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

p-toluidine
106-49-0

p-toluidine

dimethyl 2,6‐dimethyl‐1,2‐dihydroquinoline‐2,4‐dicarboxylate
1333149-53-3

dimethyl 2,6‐dimethyl‐1,2‐dihydroquinoline‐2,4‐dicarboxylate

Conditions
ConditionsYield
With TiO2 nanoparticles In neat (no solvent) at 80℃; for 1h; Green chemistry;98%
With iodine In acetonitrile at 50℃; for 12h;94%
With N-chloro-succinimide; O,O-bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) hydrazine-1,2-bis(carbothioate) In acetonitrile at 60℃; Green chemistry;92%
With lithium carbonate; magnesium bromide In neat (no solvent) at 60℃; for 1h; regioselective reaction;78%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

trimethyl orthoformate
149-73-5

trimethyl orthoformate

methyl 2,2-dimethoxypropionate
10076-48-9

methyl 2,2-dimethoxypropionate

Conditions
ConditionsYield
With sulfuric acid In methanol for 5h; Heating;97%
With sulfuric acid In methanol for 4h; Reflux;77%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

p-toluidine
106-49-0

p-toluidine

2-methyl-4-(4-methyl-anilino)-5-oxo-1-p-tolyl-2,5-dihydro-pyrrole-2-carboxylic acid methyl ester
26458-39-9

2-methyl-4-(4-methyl-anilino)-5-oxo-1-p-tolyl-2,5-dihydro-pyrrole-2-carboxylic acid methyl ester

Conditions
ConditionsYield
In dichloromethane at 20 - 25℃; for 1h; Irradiation;97%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

4-chloro-aniline
106-47-8

4-chloro-aniline

methyl 3-(4-chloroanilino)-1-(4-chlorophenyl)-5-methyl-2-oxo-3-pyrroline-5-carboxylate
141214-22-4

methyl 3-(4-chloroanilino)-1-(4-chlorophenyl)-5-methyl-2-oxo-3-pyrroline-5-carboxylate

Conditions
ConditionsYield
In dichloromethane at 20 - 25℃; for 1h; Irradiation;97%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

(4aR,5R,6S)-6-tert-butyldimethylsilyloxy-4,4a,5,6,7,8-hexahydro-4a,5-dimethyl-2(3H)-naphthalenone
188120-44-7

(4aR,5R,6S)-6-tert-butyldimethylsilyloxy-4,4a,5,6,7,8-hexahydro-4a,5-dimethyl-2(3H)-naphthalenone

zinc(II) chloride
7646-85-7

zinc(II) chloride

lithium hexamethyldisilazane
4039-32-1

lithium hexamethyldisilazane

(4R,6R,7R,8S)-8-t-Butyldimethylsilyloxy-4-(1'-hydroxy-1'-methoxycarbonyl)ethyl-6,7-dimethylbicyclo[4,4,0]deca-1-en-3-one
194789-70-3

(4R,6R,7R,8S)-8-t-Butyldimethylsilyloxy-4-(1'-hydroxy-1'-methoxycarbonyl)ethyl-6,7-dimethylbicyclo[4,4,0]deca-1-en-3-one

Conditions
ConditionsYield
In tetrahydrofuran; hexane97%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

(furan-2-yloxy)-trimethylsilane
61550-02-5

(furan-2-yloxy)-trimethylsilane

(1'R,4S)-4-(1'-hydroxy-1'-methoxycarbonylethyl)-5-oxacyclopent-2-enone

(1'R,4S)-4-(1'-hydroxy-1'-methoxycarbonylethyl)-5-oxacyclopent-2-enone

Conditions
ConditionsYield
With 2,2,2-trifluoroethanol; (R)-N-[2-(2,4,6-trimethylbenzyl)aminophenyl]-S-(4-biphenyl)-S-methylsulfoximine; copper(II) bis(trifluoromethanesulfonate) In diethyl ether at 20℃; Vinylogous Mukaiyama-type aldol reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;97%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

aniline
62-53-3

aniline

dimethyl 2‐methyl‐1,2‐dihydroquinoline‐2,4‐dicarboxylate
120453-92-1

dimethyl 2‐methyl‐1,2‐dihydroquinoline‐2,4‐dicarboxylate

Conditions
ConditionsYield
With iodine In acetonitrile at 50℃; for 13h;97%
With TiO2 nanoparticles In neat (no solvent) at 80℃; for 1.5h; Green chemistry;97%
With nitric acid In water; acetonitrile at 80℃; Inert atmosphere;95%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

4-Aminobenzonitrile
873-74-5

4-Aminobenzonitrile

dimethyl 6-cyano-2-methyl-1,2-dihydroquinoline-2,4-dicarboxylate
1403657-23-7

dimethyl 6-cyano-2-methyl-1,2-dihydroquinoline-2,4-dicarboxylate

Conditions
ConditionsYield
With bismuth(lll) trifluoromethanesulfonate In acetonitrile at 100℃; under 7500.75 Torr; for 10h; Temperature; Time; Microwave irradiation;97%
With lithium carbonate; magnesium bromide In neat (no solvent) at 90℃; for 5h; regioselective reaction;94%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

(2E, 2'E)-dimethyl 2,2'-(hydrazine-1,2-diylidene)dipropanoate

(2E, 2'E)-dimethyl 2,2'-(hydrazine-1,2-diylidene)dipropanoate

Conditions
ConditionsYield
With carbazic acid In neat (no solvent) at 70℃; for 0.5h; Green chemistry;97%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

C15H30O2Si

C15H30O2Si

C19H36O5Si

C19H36O5Si

Conditions
ConditionsYield
Stage #1: C15H30O2Si With lithium hexamethyldisilazane In tetrahydrofuran at -78 - -45℃; for 2h; Inert atmosphere;
Stage #2: pyruvic acid methyl ester In tetrahydrofuran at -45℃; for 1h; Inert atmosphere;
97%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

methyl 2-methyl-2-(dimethylphenylsilyl)-3-butenoate
106046-48-4

methyl 2-methyl-2-(dimethylphenylsilyl)-3-butenoate

dimethyl 5-hydroxy-2,5-dimethyl-2-hexedioate

dimethyl 5-hydroxy-2,5-dimethyl-2-hexedioate

Conditions
ConditionsYield
With titanium tetrachloride In dichloromethane for 3h; from -78 deg C to RT;96%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

methyl-2-dimethoxyphosphoryl-2-dichlorophosphinoxypropanoate

methyl-2-dimethoxyphosphoryl-2-dichlorophosphinoxypropanoate

Conditions
ConditionsYield
With phosphorus trichloride at 20℃; for 1h;96%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

(Z)-1-(tert-butylthio)-1-trimethylsilyloxyprop-1-ene
76943-94-7

(Z)-1-(tert-butylthio)-1-trimethylsilyloxyprop-1-ene

(2S,3S)-tert-butyl 3-hydroxy-3-methoxycarbonyl-2-methylbutanethioate

(2S,3S)-tert-butyl 3-hydroxy-3-methoxycarbonyl-2-methylbutanethioate

Conditions
ConditionsYield
With hydrogenchloride; (S,S)-Cu(II) complex from bis(oxazolinyl) ligand and Cu(OTf)2 In dichloromethane at -78℃;96%
pyruvic acid methyl ester
600-22-6

pyruvic acid methyl ester

1-methoxy-2-methyl-1-trimethylsiloxy-1-propene
31469-15-5

1-methoxy-2-methyl-1-trimethylsiloxy-1-propene

dimethyl 3-hydroxy-2,2,3-trimethylbutanedioate

dimethyl 3-hydroxy-2,2,3-trimethylbutanedioate

Conditions
ConditionsYield
[bis(diphenylphosphino)methane]bis(propenyl)Ru(II) In tetrahydrofuran at 65℃; for 20h; Condensation; aldol addition;96%
Stage #1: pyruvic acid methyl ester; 1-methoxy-2-methyl-1-trimethylsiloxy-1-propene With pentafluorophenylammonium trifluoromethanesulfonimide In toluene at -50 - -45℃; for 1h; Mukaiyama reaction; Inert atmosphere;
Stage #2: With hydrogenchloride In methanol; water at 20 - 25℃; for 1h; Mukaiyama reaction; Inert atmosphere;
68%

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