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AstaTech ( Chengdu) BioPharmaceutical Corp.

Quality assurance, stable process and affordable priceAppearance:detailed see specifications Storage:enquiry Package:according to the clients requirement Application:Pharmaceutical intermediates Transportation:Normal Port:chengdu

1-Methylindole

Cas:603-76-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

1-Methylindole Manufacturer/High quality/Best price/In stock

Cas:603-76-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 1-Methylindole supplier in China

Cas:603-76-9

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------

High purity 603-76-9 N-METHYLINDOLE

Cas:603-76-9

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

inquiry

Jinan Finer Chemical Co., Ltd

Product description: Product name 1-Methylindole CAS number 603-76-9 Assay ≥99% Appearance Light yellow transparent liquid Capacity 200mt/year Application Pharmaceutical inte

1-Methylindole

Cas:603-76-9

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

1-Methylindole Product Name: 1-Methylindole Molecular Weight: 131.17 CAS NO: 603-76-9 EC NO: 210-057-5 Molecular Formula: C9H9N

1-Methylindole

Cas:603-76-9

Min.Order:1 Kilogram

FOB Price: $2.0 / 3.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

N-Methylindole

Cas:603-76-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

1-Methylindole / LIDE PHARMA- Factory supply / Best price

Cas:603-76-9

Min.Order:1 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

603-76-9 1-Methylindole

Cas:603-76-9

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 603-76-9 with best quality

Cas:603-76-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name: 1-Methylindole Synonyms: N-METHYLINDOLE;1-Methyl-1H-indole;Indole, 1-methyl-;1-METHYLINDOLE (N-);1-METHYLINDOLE;1-METHYLINDOL;1H-Indole, 1-methyl-;L-Methylindole CAS: 603

1-Methylindole CAS: 603-76-9

Cas:603-76-9

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

1)quick response within 12 hours; 2)quality guarantee: all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. 3) oem/odm available; 4) rea

1-METHYLINDOLE (N-)CAS NO.:603-76-9

Cas:603-76-9

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is

1-Methylindole CAS: 603-76-9

Cas:603-76-9

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Methylindole 603-76-9

Cas:603-76-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

1-Methylindole CAS:603-76-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediat

1-Methylindole CAS:603-76-9

Cas:603-76-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists

1-METHYLINDOLE 603-76-9

Cas:603-76-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

N-Methylindole

Cas:603-76-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

1-Methylindole

Cas:603-76-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

METHYLINDOLE

Cas:603-76-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1-Methylindole

Cas:603-76-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1-Methylindole

Cas:603-76-9

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1-Methylindole

Cas:603-76-9

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

advantage: 1. The best price, satisfactory quality; 2. customers have the right to choose the delivery of parcels (EMS, DHL, FedEx, UPS); 3. customers have the right to choose from the recent effective packaging methods of their products packaging

High Quality 603-76-9 in China 1-Methylindole factory

Cas:603-76-9

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 1-Methylindole

Cas:603-76-9

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

1-Methylindole

Cas:603-76-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1-Methylindole CAS NO.603-76-9

Cas:603-76-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 1-Methylindole CAS No.: 603-76-9 Molecule Formula:C9H9N Molecule Weight:131.17 Purity: 98.0% Package: 200kg/drum Description:Light yellow oil-like liquid Manufacture Standards:Enterprise Standard TEST

Lower Price 1-Methylindole

Cas:603-76-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Product Name:1-Methylindole CAS No:603-76-9 Synonym

1-Methylindole

Cas:603-76-9

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

1-Methylindole Chemical Properties Melting point 61.2°C (estimate) Boiling point 133 °C26 mm Hg(lit.) density 1.051 g/mL at 20 °C(lit.) refractive index n20/D 1.606(lit.) Fp >230 °F storage temp. Refrigerato

1-Methylindole

Cas:603-76-9

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

1-Methylindole

Cas:603-76-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

indole
120-72-9

indole

methyl iodide
74-88-4

methyl iodide

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 0 - 20℃; for 0.5h;99%
Stage #1: indole With sodium hydride In tetrahydrofuran Inert atmosphere;
Stage #2: methyl iodide at 0 - 20℃; for 0.5h; Inert atmosphere;
99%
Stage #1: indole With sodium hydride In tetrahydrofuran at 0 - 20℃; for 1.25h;
Stage #2: methyl iodide In tetrahydrofuran at 0 - 20℃; for 0.5h;
99%
N-methylindoline
824-21-5

N-methylindoline

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With H8O20P8Pt2(4-)*4C34H72N(1+) In methanol Inert atmosphere; Irradiation;99%
With bis(1,5-cyclooctadiene)diiridium(I) dichloride In para-xylene at 130℃; for 20h; Catalytic behavior; Temperature; Solvent; Reagent/catalyst; Inert atmosphere; Sealed tube;99%
With oxygen In N,N-dimethyl acetamide at 20℃; Schlenk technique; Irradiation;95%
2,3-diiodo-1-methyl-1H-indole
180623-97-6

2,3-diiodo-1-methyl-1H-indole

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
Stage #1: 2,3-diiodo-1-methyl-1H-indole With tert.-butyl lithium In tetrahydrofuran; pentane at -78℃; for 0.333333h;
Stage #2: With ammonium chloride In tetrahydrofuran; water; pentane at -78 - 20℃;
99%
indole
120-72-9

indole

MeX

MeX

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With potassium hydroxide In acetone99%
Multi-step reaction with 3 steps
1.1: n-BuLi; CO2 / tetrahydrofuran / -78 °C
1.2: t-BuLi / tetrahydrofuran / -78 °C
1.3: 91 percent / ICH2CH2I
2.1: 100 percent / KOH / dimethylformamide
3.1: n-BuLi; ZnCl2
3.2: Pd(PPh3)2Cl2; 2-iodoindole
View Scheme
Multi-step reaction with 4 steps
1.1: 90 percent
2.1: I2; KOH / dimethylformamide
3.1: n-Bu4NHSO4 / dimethylformamide
4.1: t-BuLi / tetrahydrofuran; pentane / 0.33 h / -78 °C
4.2: 99 percent / NH4Cl / H2O; tetrahydrofuran; pentane / -78 - 20 °C
View Scheme
indole
120-72-9

indole

methyl halide

methyl halide

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
Stage #1: indole With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h; Inert atmosphere; Sealed tube;
Stage #2: methyl halide In tetrahydrofuran; mineral oil at 0 - 20℃; Inert atmosphere; Sealed tube;
99%
Stage #1: indole With sodium hydroxide In dimethyl sulfoxide
Stage #2: methyl halide In dimethyl sulfoxide at 10 - 15℃; for 3h;
Stage #1: indole With sodium hydride In N,N-dimethyl-formamide at 0 - 23℃; for 0.5h; Inert atmosphere;
Stage #2: methyl halide In N,N-dimethyl-formamide at 0 - 23℃; Inert atmosphere;
1-methyl-1H-indole-2,3,5,7-d4

1-methyl-1H-indole-2,3,5,7-d4

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With tris(pentafluorophenyl)borate; water In chloroform at 80℃; for 24h; Sealed tube;99%
3H-indole
271-26-1

3H-indole

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With cetyltrimethylammonium chloride at 150 - 170℃; under 12001.2 - 24002.4 Torr; Inert atmosphere; Sealed tube; Autoclave;98.8%
indole
120-72-9

indole

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 50 - 130℃; for 9h;98%
With tributyl-amine In N,N-dimethyl-formamide at 285℃; under 112511 Torr; for 0.05h;98%
With 1,4-diaza-bicyclo[2.2.2]octane In N,N-dimethyl-formamide at 94 - 95℃; for 8h;97%
indole
120-72-9

indole

methyl bromide
74-83-9

methyl bromide

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With potassium hydroxide In dimethyl sulfoxide at 20℃;97%
Stage #1: indole With potassium hydroxide In N,N-dimethyl-formamide at 0℃; for 0.333333h;
Stage #2: methyl bromide In N,N-dimethyl-formamide at 0 - 20℃; for 1h;
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 24h;
Stage #1: indole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;
Stage #2: methyl bromide In N,N-dimethyl-formamide at 0℃;
With potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 24h; Inert atmosphere;
4-bromo-1-methyl-1H-indole
590417-55-3

4-bromo-1-methyl-1H-indole

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With potassium tert-butylate; benzyl alcohol In N,N-dimethyl-formamide at 130℃; for 2.5h; Reagent/catalyst; Schlenk technique; Inert atmosphere;96%
1-benzenesulfonylindole
40899-71-6

1-benzenesulfonylindole

potassium methanolate
865-33-8

potassium methanolate

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
In acetonitrile at 20℃; for 4h; Sealed tube; Glovebox;96%
In acetonitrile at 20℃;96%
5-chloro-1-methyl-1H-indole
112398-75-1

5-chloro-1-methyl-1H-indole

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With potassium tert-butylate; N,N-dimethyl-formamide In dimethyl sulfoxide at 35℃; for 24h; Schlenk technique; Inert atmosphere; Irradiation;96%
indole
120-72-9

indole

dimethyl sulfate
77-78-1

dimethyl sulfate

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With potassium tert-butylate In acetone at 20℃; for 1h;94%
With potassium hydroxide In acetone Methylation;93%
With sodium amide; toluene
With potassium carbonate
N-methyl-N-(2-vinylphenyl)amine
5339-28-6

N-methyl-N-(2-vinylphenyl)amine

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With p-benzoquinone; lithium chloride; dichloro bis(acetonitrile) palladium(II) In tetrahydrofuran for 18h; Heating;94%
N-methyl-3-formylindole
19012-03-4

N-methyl-3-formylindole

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With palladium nanoparticles supported on fibrous silica In cyclohexane at 130℃; for 22h; Molecular sieve;94%
N-methyl-2-indolinone
61-70-1

N-methyl-2-indolinone

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With dimethylethylsilane; 2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; bis(pentafluorophenyl)borohydride In dichloromethane; toluene at 20℃; for 24h; Inert atmosphere; Sealed tube; chemoselective reaction;94%
3-bromo-1-methyl-1H-indole
81471-20-7

3-bromo-1-methyl-1H-indole

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With sodium tetrahydroborate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran at 20℃; for 19h; Reagent/catalyst; Time; Inert atmosphere;93%
With di-tert-butyl peroxide; caesium carbonate; isopropyl alcohol at 120℃; for 24h; Inert atmosphere;90 %Chromat.
3-bromo-1-methyl-1H-indole
81471-20-7

3-bromo-1-methyl-1H-indole

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium tetrahydroborate; N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran at 25℃; for 19h; Inert atmosphere;93%
1-methyl-5-iodoindole
280563-07-7

1-methyl-5-iodoindole

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With potassium tert-butylate; benzyl alcohol In N,N-dimethyl-formamide at 90℃; for 2h; Reagent/catalyst; Schlenk technique; Inert atmosphere;92%
With potassium tert-butylate; benzaldehyde In N,N-dimethyl-formamide at 90℃; for 2h; Schlenk technique; Inert atmosphere;86%
With 1,3-bis(2,6-diisopropylphenyl)-2,4-diphenylimidazole In N,N-dimethyl-formamide at 20℃; for 36h; Glovebox;85%
With 2-(2-methoxyethoxy)ethyl alcohol; oxygen; sodium hydride In 1,4-dioxane at 20℃; for 24h; Schlenk technique; chemoselective reaction;76%
5-bromo-1-methyl-H-indole
10075-52-2

5-bromo-1-methyl-H-indole

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With 1,1,1,2,2,2-hexamethyldisilane; potassium methanolate; acetonitrile at 25℃; for 5h; Reagent/catalyst; Inert atmosphere; Glovebox; Sealed tube;92%
With 2-H-1,3-di-tert-butyl-1,3,2-diazaphosphorinane; 2,2'-azobis(isobutyronitrile) In toluene at 90℃; for 12h;70%
With tributyl-amine; tetrabutylammonium tetrafluoroborate In acetonitrile at 20℃; for 1.8h; Inert atmosphere; Electrolysis;64%
1-(p-toluenesulfonyl)-1H-indole
31271-90-6

1-(p-toluenesulfonyl)-1H-indole

potassium methanolate
865-33-8

potassium methanolate

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
In acetonitrile at 20℃; for 4h; Solvent; Sealed tube; Glovebox;92%
In acetonitrile at 20℃; Solvent;95 %Chromat.
1-methyl-3-indolecarboxylic acid
32387-21-6

1-methyl-3-indolecarboxylic acid

1,1-Diphenylmethanol
91-01-0

1,1-Diphenylmethanol

A

3-(1,1-diphenylmethyl)-1-methyl-1H-indole
53924-28-0

3-(1,1-diphenylmethyl)-1-methyl-1H-indole

B

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With sodium tetrachloroaurate(III) dihyrate; sodium 3-(diphenylphosphanyl)benzenesulfonate In water at 120℃; for 16h; Reagent/catalyst; Solvent; Sealed tube;A 91%
B 9%
With sodium tetrachloroaurate(III) dihyrate; sodium 3-(diphenylphosphanyl)benzenesulfonate In water at 120℃; for 16h; Reagent/catalyst; Solvent; Sealed tube;A 5%
B 47%
With sodium tetrachloroaurate(III) dihyrate; sodium 3-(diphenylphosphanyl)benzenesulfonate In water at 120℃; for 16h; Reagent/catalyst; Solvent; Sealed tube;A 47%
B 5%
indole
120-72-9

indole

methy halide

methy halide

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
Stage #1: indole With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 1h; Inert atmosphere;
Stage #2: methy halide at 0 - 20℃; for 24h;
90%
indole
120-72-9

indole

tetramethylammonium fluoride
373-68-2

tetramethylammonium fluoride

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
In toluene at 100℃; for 3h;90%
2′-N,N-dimethylaminophenylacetylene
219605-52-4

2′-N,N-dimethylaminophenylacetylene

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With ethanol at 120℃; for 4h; Microwave irradiation; Inert atmosphere; Green chemistry;89%
Dimethyl oxalate
553-90-2

Dimethyl oxalate

indole
120-72-9

indole

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide for 0.166667h; Heating;88%
With potassium tert-butylate In N,N-dimethyl-formamide for 0.25h; Heating;88%
indole
120-72-9

indole

trifluoroacetic acid-methyl ester
431-47-0

trifluoroacetic acid-methyl ester

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
Stage #1: indole With potassium tert-butylate In N,N-dimethyl-formamide at 20℃; for 0.0833333h;
Stage #2: trifluoroacetic acid-methyl ester In N,N-dimethyl-formamide for 10h;
88%
2-bromo-1-methyl-1H-indole
89246-30-0

2-bromo-1-methyl-1H-indole

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium tetrahydroborate; N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran at 25℃; for 0.8h; Reagent/catalyst; Inert atmosphere;87%
1-indoline
496-15-1

1-indoline

1-methylindole
603-76-9

1-methylindole

Conditions
ConditionsYield
With copper(II) choride dihydrate; oxygen In dimethyl sulfoxide at 20 - 120℃; for 0.166667h;87%
Multi-step reaction with 2 steps
1: sodium hydride / tetrahydrofuran; mineral oil / 24 h / 20 °C
2: tris(pentafluorophenyl)borate / para-xylene / 22 h / 150 °C / Inert atmosphere; Sealed tube
View Scheme
Multi-step reaction with 2 steps
1: triethylamine / dimethyl sulfoxide / 20 h / 150 °C / Sealed tube; Schlenk technique; Inert atmosphere
2: sodium carbonate / ethyl acetate / 24 h / 120 °C / Sealed tube; Green chemistry
View Scheme
Multi-step reaction with 2 steps
1: acetic acid; sodium cyanoborohydride / water; methanol / 1 h / 20 °C
2: dichloro[1,3-bis(2-methylphenyl)-2-imidazolidinylidene](benzylidene) (tricyclohexylphosphine) ruthenium(II); oxygen / ethyl acetate / 46 h / 70 °C / 760.05 Torr / Sealed tube
View Scheme
1-methylindole
603-76-9

1-methylindole

1,1-dicyano-2,2-bis(trifluoromethyl)ethene
1113-69-5

1,1-dicyano-2,2-bis(trifluoromethyl)ethene

2-[2,2,2-Trifluoro-1-(1-methyl-1H-indol-3-yl)-1-trifluoromethyl-ethyl]-malononitrile

2-[2,2,2-Trifluoro-1-(1-methyl-1H-indol-3-yl)-1-trifluoromethyl-ethyl]-malononitrile

Conditions
ConditionsYield
100%
1-methylindole
603-76-9

1-methylindole

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

tri(1-methyl-1H-indole-3-yl)methane
27065-95-8

tri(1-methyl-1H-indole-3-yl)methane

Conditions
ConditionsYield
With toluene-4-sulfonic acid In methanol at 70℃; for 0.166667h;100%
With iodine In acetonitrile at 20℃; for 0.133333h;90%
With acid-washed montmorillonite K10 clay at 20℃;87%
With acid-washed montmorillonite K10 clay (acid-clay) at 20℃;
1-methylindole
603-76-9

1-methylindole

2,3-dicyano-5,6-dichloro-p-benzoquinone
84-58-2

2,3-dicyano-5,6-dichloro-p-benzoquinone

4,5-Dichloro-3-hydroxy-1-(1-methyl-1H-indol-3-yl)-6-oxo-cyclohexa-2,4-diene-1,2-dicarbonitrile
61995-39-9

4,5-Dichloro-3-hydroxy-1-(1-methyl-1H-indol-3-yl)-6-oxo-cyclohexa-2,4-diene-1,2-dicarbonitrile

Conditions
ConditionsYield
In 1,4-dioxane for 24h; Ambient temperature;100%
1-methylindole
603-76-9

1-methylindole

3-iodo-1-methyl-1H-indole
85092-84-8

3-iodo-1-methyl-1H-indole

Conditions
ConditionsYield
With N-iodo-succinimide In N,N-dimethyl-formamide at 0℃; for 1.5h; Inert atmosphere;100%
With potassium hydroxide; iodine In N,N-dimethyl-formamide Ambient temperature;98%
With iodine; potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere; Schlenk technique; Glovebox;97%
1-methylindole
603-76-9

1-methylindole

nitrostyrene
5153-67-3

nitrostyrene

1-methyl-3-(2-nitro-1-phenylethyl)-1H-indole
109811-96-3

1-methyl-3-(2-nitro-1-phenylethyl)-1H-indole

Conditions
ConditionsYield
With Zn(2+)*2C6H6NO2S2(1-) In ethanol at 20℃; for 24h;100%
With 1H-pyrrolo[2,3-b]pyridinium substituted-borate salt In toluene at 0 - 20℃; for 24h;99%
Stage #1: nitrostyrene With (S)-10,10'-bis[(S)-4-isopropyl-4,5-dihydrooxazol-2-yl]-9,9'-biphenanthrene; zinc(II) trifluoroacetate In diethyl ether at 20℃; for 0.25h; Inert atmosphere;
Stage #2: 1-methylindole In diethyl ether at 20℃; Friedel-Crafts alkylation; Inert atmosphere;
99%
1-methylindole
603-76-9

1-methylindole

methyl vinyl ketone
78-94-4

methyl vinyl ketone

4-(1-methyl-1H-indol-3-yl)-butan-2-one
91956-43-3

4-(1-methyl-1H-indol-3-yl)-butan-2-one

Conditions
ConditionsYield
With trityl tetrafluoroborate In dichloromethane Inert atmosphere;100%
With rac-9-phenyl-9H-cyclopenta[1,2-c:4,3-c']diphenanthren-9-ylium tetrakis(3,5-bis(tri-fluoromethyl)phenyl)borate In dichloromethane at 20℃; for 24h; Friedel-Crafts Alkylation; Glovebox; Inert atmosphere;100%
hafnium tetrachloride In acetonitrile at 20℃; for 0.333333h;99%
1-methylindole
603-76-9

1-methylindole

4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

3-[(4-chlorophenyl)(1-methyl-1H-indol-3-yl)methyl]-1-methyl-1H-indole

3-[(4-chlorophenyl)(1-methyl-1H-indol-3-yl)methyl]-1-methyl-1H-indole

Conditions
ConditionsYield
With o-benzenedisulfonimide at 20℃; for 0.0833333h; Friedel Crafts alkylation; neat (no solvent);100%
With cellulose sulfuric acid at 50℃; for 0.333333h; Neat (no solvent); Grinding; Combinatorial reaction / High throughput screening (HTS); chemoselective reaction;98%
With N-Bromosuccinimide at 20℃; for 6h;96%
1-methylindole
603-76-9

1-methylindole

(E)-1,3-diphenyl-2-propen-1-ol
62668-02-4

(E)-1,3-diphenyl-2-propen-1-ol

3-((E)-1,3-diphenyl-2-propenyl)-1-methyl-1H-indole

3-((E)-1,3-diphenyl-2-propenyl)-1-methyl-1H-indole

Conditions
ConditionsYield
With 5,11,17,23-tetrasulfonate-25,26,27,28-tetrakis(propoxy)calix[4]arene tetrasodium salt In water at 50℃; for 61h; Reagent/catalyst; Concentration; Time; Green chemistry;100%
With magnetic Fe3O4-grafted calix[6]arene sulfonic acid In water at 50℃; for 24h; Catalytic behavior; Reagent/catalyst;99.9%
With zinc dibromide In neat (no solvent) for 1.5h; Milling; Green chemistry; chemoselective reaction;92%
1-methylindole
603-76-9

1-methylindole

4,4'-Dimethoxybenzhydrol
728-87-0

4,4'-Dimethoxybenzhydrol

3-[bis(4-methoxyphenyl)methyl]-1-methyl-1H-indole

3-[bis(4-methoxyphenyl)methyl]-1-methyl-1H-indole

Conditions
ConditionsYield
With 5,11,17,23-tetrasulfonate-25,26,27,28-tetrakis(propoxy)calix[4]arene tetrasodium salt In water at 50℃; for 24h; Reagent/catalyst; Concentration; Green chemistry;100%
With magnetic Fe3O4-grafted calix[4]arene sulfonic acid In water at 50℃; for 25h; Catalytic behavior; Reagent/catalyst;99.9%
With sodium tetrachloroaurate(III) dihydrate; sodium 3-(diphenylphosphanyl)benzenesulfonate In water at 80℃; for 16h; Sealed tube;95%
With o-benzenedisulfonimide In neat (no solvent) at 20℃; for 0.25h; Friedel-Crafts Alkylation;94%
With dodecylbenzene-sulphonic acid In water at 80℃; for 24h; Friedel-Crafts reaction;92%
1-methylindole
603-76-9

1-methylindole

thuriferic acid methyl ester
918108-96-0

thuriferic acid methyl ester

C32H31NO8
1032712-17-6

C32H31NO8

Conditions
ConditionsYield
With indium(III) bromide In dichloromethane at 20℃; for 2h; Michael addition; diastereoselective reaction;100%
1-methylindole
603-76-9

1-methylindole

C10H6(N(CH3)2)2(BC8H14)(1+)*N(SO2CF3)2(1-)=(C10H6(N(CH3)2)2(BC8H14))N(SO2CF3)2

C10H6(N(CH3)2)2(BC8H14)(1+)*N(SO2CF3)2(1-)=(C10H6(N(CH3)2)2(BC8H14))N(SO2CF3)2

A

3-(9-borabicyclo[3.3.1]nonan-9-yl)-1-methyl-1H-indole
1283232-87-0

3-(9-borabicyclo[3.3.1]nonan-9-yl)-1-methyl-1H-indole

B

C2HF6NO4S2*C14H18N2

C2HF6NO4S2*C14H18N2

Conditions
ConditionsYield
In dichloromethane at 50℃; for 2h; Sealed vessel; Inert atmosphere;A 100%
B n/a
1-methylindole
603-76-9

1-methylindole

4,4′,4″‑[(1,3,5‑triazine‑2,4,6‑triyl)tris(oxy)]tribenzaldehyde
3140-75-8

4,4′,4″‑[(1,3,5‑triazine‑2,4,6‑triyl)tris(oxy)]tribenzaldehyde

C78H63N9O3
1431159-05-5

C78H63N9O3

Conditions
ConditionsYield
With silica sulfuric acid In acetonitrile at 20℃; for 0.5h; Friedel-Crafts Alkylation;100%
(E)‐1‐(1‐methyl‐1H‐imidazole‐2‐yl)‐but‐2‐en‐1‐one
860772-38-9

(E)‐1‐(1‐methyl‐1H‐imidazole‐2‐yl)‐but‐2‐en‐1‐one

1-methylindole
603-76-9

1-methylindole

1-(1-methyl-1H-imidazol-2-yl)-3-(1-methyl-1H-indol-3-yl)butan-1-one

1-(1-methyl-1H-imidazol-2-yl)-3-(1-methyl-1H-indol-3-yl)butan-1-one

Conditions
ConditionsYield
With [ZnIIYIII(N,N'-bis(3-methoxysalicylidene)cyclohexane-1,2-diamine)(NO3)2(o-vanillin)2(MeOH)](MeOH) In ethyl acetate at 20℃; for 72h; Friedel-Crafts Alkylation; Inert atmosphere;100%
With copper(II) nitrate trihydrate In aq. buffer at 20℃; for 72h; pH=6.5; Friedel-Crafts Alkylation;88%
With copper(II) nitrate trihydrate In aq. buffer at 20℃; for 72h; pH=6.5; Reagent/catalyst; Friedel-Crafts Alkylation; enantioselective reaction;88%
With 4,4'-dimethyl-2,2'-bipyridines; copper(II) nitrate trihydrate In acetonitrile at 20℃; for 72h; Catalytic behavior; Reagent/catalyst; Friedel-Crafts Alkylation; Inert atmosphere;80%
With copper(II) nitrate trihydrate In acetonitrile at 20℃; for 16h; pH=7; Friedel-Crafts Alkylation;
1-methylindole
603-76-9

1-methylindole

1-(2,4-dimethoxy-phenyl)-1,3-dihydro-isobenzofuran
23949-31-7

1-(2,4-dimethoxy-phenyl)-1,3-dihydro-isobenzofuran

C25H25NO3

C25H25NO3

Conditions
ConditionsYield
With iron(III) chloride In 1,4-dioxane at 20℃; for 6h;100%
1-methylindole
603-76-9

1-methylindole

1,1'-dimethyl-2',3'-dihydro-1H,1'H-2,3'-biindole

1,1'-dimethyl-2',3'-dihydro-1H,1'H-2,3'-biindole

Conditions
ConditionsYield
With dimethylaluminum chloride In hexane; toluene at -30℃; for 18h; Temperature;100%
1-methylindole
603-76-9

1-methylindole

Et3SiD
1631-33-0

Et3SiD

1-methyl-1H-indole-2,3-d2

1-methyl-1H-indole-2,3-d2

Conditions
ConditionsYield
With norborn-2-ene; carbonyl bis(hydrido)tris(triphenylphosphine)ruthenium(II) In toluene at 150℃; for 16h; Inert atmosphere;100%
2-phenylethynyl-quinoline-3-carbaldehyde
868765-12-2

2-phenylethynyl-quinoline-3-carbaldehyde

1-methylindole
603-76-9

1-methylindole

1-(1-methyl-1H-indol-3-yl)-3-phenyl-1H-pyrano[4,3-b]quinoline

1-(1-methyl-1H-indol-3-yl)-3-phenyl-1H-pyrano[4,3-b]quinoline

Conditions
ConditionsYield
With silver trifluoromethanesulfonate In 1,2-dichloro-ethane for 1 - 24h; Inert atmosphere; Reflux;100%
1-methylindole
603-76-9

1-methylindole

7-chloro-2-(phenylethynyl)quinoline-3-carbaldehyde
1421925-29-2

7-chloro-2-(phenylethynyl)quinoline-3-carbaldehyde

7-chloro-1-(1-methyl-1H-indol-3-yl)-3-phenyl-1H-pyrano[4,3-b]quinoline

7-chloro-1-(1-methyl-1H-indol-3-yl)-3-phenyl-1H-pyrano[4,3-b]quinoline

Conditions
ConditionsYield
With silver trifluoromethanesulfonate In 1,2-dichloro-ethane for 1 - 24h; Inert atmosphere; Reflux;100%
1-methylindole
603-76-9

1-methylindole

1-methyl-3-propyl-1H-indole
1170697-31-0

1-methyl-3-propyl-1H-indole

2-(1’-methylindol-3’-yl)-1-methyl-3-propylindole

2-(1’-methylindol-3’-yl)-1-methyl-3-propylindole

Conditions
ConditionsYield
Stage #1: 1-methyl-3-propyl-1H-indole With 2,6-di-tert-butyl-pyridine; trifluoromethylsulfonic anhydride; dimethyl sulfoxide In dichloromethane; dimethyl sulfoxide at -78℃; for 0.25h; Inert atmosphere;
Stage #2: 1-methylindole In dichloromethane; dimethyl sulfoxide for 0.25h; Inert atmosphere;
100%
1-methylindole
603-76-9

1-methylindole

1-benzyl-7-(trifluoromethyl)indoline-2,3-dione
1263090-20-5

1-benzyl-7-(trifluoromethyl)indoline-2,3-dione

C25H19F3N2O2

C25H19F3N2O2

Conditions
ConditionsYield
With C24H30N8; scandium tris(trifluoromethanesulfonate) In acetonitrile at 20℃; for 18h; Friedel-Crafts Alkylation; Inert atmosphere; Molecular sieve; chemoselective reaction;100%
1-methylindole
603-76-9

1-methylindole

trans-1-(4-fluorophenyl)-2-nitro-ethene
706-08-1, 5153-69-5

trans-1-(4-fluorophenyl)-2-nitro-ethene

3-(1-(4-fluorophenyl)-2-nitroethyl)-1-methyl-1H-indole
1430076-20-2

3-(1-(4-fluorophenyl)-2-nitroethyl)-1-methyl-1H-indole

Conditions
ConditionsYield
With Zn(2+)*2C6H6NO2S2(1-) In ethanol at 20℃; for 24h;100%
With C22H35N4S(1+)*BF4(1-) In dichloromethane at 20℃; for 44h; Friedel-Crafts Alkylation; Inert atmosphere;92%
With rose bengal In water at 60℃; Friedel-Crafts Alkylation; Irradiation;81%
With 2C32H12BF24(1-)*C13H16N4S(2+) In chloroform-d1 at 20℃; Inert atmosphere;
1-methylindole
603-76-9

1-methylindole

C19H16BF3NO(1-)

C19H16BF3NO(1-)

((4R*,6R*)-6-(1-methyl-1H-indol-3-yl)-4-(o-tolyl)-1,4,5,6-tetrahydropyridin-3-yl)(phenyl)methanone

((4R*,6R*)-6-(1-methyl-1H-indol-3-yl)-4-(o-tolyl)-1,4,5,6-tetrahydropyridin-3-yl)(phenyl)methanone

Conditions
ConditionsYield
With trifluoroacetic acid In tetrahydrofuran; methanol at 20℃; diastereoselective reaction;100%
1-methylindole
603-76-9

1-methylindole

6-chloro-7H-purine
87-42-3

6-chloro-7H-purine

6-(1-methyl-1H-indol-3-yl)-7H-purine

6-(1-methyl-1H-indol-3-yl)-7H-purine

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; 1,1,1,3',3',3'-hexafluoro-propanol at 60℃; for 24h; Reagent/catalyst;100%
1-methylindole
603-76-9

1-methylindole

formaldehyd
50-00-0

formaldehyd

dimethyl amine
124-40-3

dimethyl amine

3-(N,N-dimethylaminomethyl)-1-methylindole
52972-61-9

3-(N,N-dimethylaminomethyl)-1-methylindole

Conditions
ConditionsYield
Stage #1: 1-methylindole; formaldehyd; dimethyl amine With acetic acid In water at 0 - 50℃; Mannich reaction;
Stage #2: With sodium hydroxide In water
99%
With acetic acid at 0 - 50℃; for 14h;91%
With zinc(II) chloride In ethanol at 20℃; for 2.5h; Mannich reaction;82%
1-methylindole
603-76-9

1-methylindole

1-methyl-1H-indole-2,3-dione
2058-74-4

1-methyl-1H-indole-2,3-dione

1-methyl-3,3-bis(1-methyl-1H-indol-3-yl)-2,3-dihydro-1H-indol-2-one
75833-69-1

1-methyl-3,3-bis(1-methyl-1H-indol-3-yl)-2,3-dihydro-1H-indol-2-one

Conditions
ConditionsYield
With C19H22N4; scandium tris(trifluoromethanesulfonate) In acetonitrile at 20℃; for 18h; Friedel-Crafts Alkylation; Inert atmosphere; Molecular sieve; chemoselective reaction;99%
In acetic acid at 35℃; for 24h;92%
With H6P2W18O62 In water at 60℃; for 0.5h;90%
1-methylindole
603-76-9

1-methylindole

4-formyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
950-81-2

4-formyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one

<4-Antipyryl-><1-methyl-3-indolyl->carbenium-tetrafluoroborate

<4-Antipyryl-><1-methyl-3-indolyl->carbenium-tetrafluoroborate

Conditions
ConditionsYield
With tetrafluoroboric acid In diethyl ether; dichloromethane for 0.5h;99%
1-methylindole
603-76-9

1-methylindole

methyl 2-methoxy-2-(piperidin-1-yl)acetate
13887-54-2

methyl 2-methoxy-2-(piperidin-1-yl)acetate

methyl 2-(1-methyl-1H-indol-3-yl)-2-(piperidin-1-yl)acetate

methyl 2-(1-methyl-1H-indol-3-yl)-2-(piperidin-1-yl)acetate

Conditions
ConditionsYield
With hafnium tetrakis(trifluoromethanesulfonate); chloro-trimethyl-silane In dichloromethane at 20℃; for 1h;99%
With Methyltrichlorosilane In acetonitrile for 39h; Ambient temperature;88%
1-methylindole
603-76-9

1-methylindole

ammonium thiocyanate
1147550-11-5

ammonium thiocyanate

N-methyl-3-thiocyanato-1H-indole
23518-17-4

N-methyl-3-thiocyanato-1H-indole

Conditions
ConditionsYield
With ammonium cerium(IV) nitrate In methanol Ambient temperature;99%
In acetonitrile at 20℃; for 3h; Electrochemical reaction; Inert atmosphere;99%
With oxygen In tetrahydrofuran at 25℃; under 750.075 Torr; for 10h; Irradiation;98%
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