-
Name
N-methylcolchiceinamide
- EINECS
- CAS No. 63917-71-5
- Density 1.24g/cm3
- Solubility
- Melting Point
- Formula C22H26 N2 O5
- Boiling Point 724.3°Cat760mmHg
- Molecular Weight 398.50
- Flash Point 391.9°C
- Transport Information
- Appearance
- Safety Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms Acetamide,N-[5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylamino)-9-oxobenzo[b]heptalen-7-yl]-(9CI); Benzo[b]heptalene, acetamide deriv.
- PSA
- LogP
Methylaminocolchicide Chemical Properties
IUPAC Name: N-[1,2,3-trimethoxy-10-(methylamino)-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Synonyms of Methylaminocolchicide (CAS NO.63917-71-5): Methylcolchaminone ; Benzo(a)heptalen-9(5H)-one, 7-acetamido-6,7-dihydro-10-methylamino-1,2,3-trimethoxy-
CAS NO: 63917-71-5
Molecular Formula: C22H26N2O5
Molecular Weight : 398.4522
Molecular Structure: .png)
H bond acceptors: 7
H bond donors: 2
Freely Rotating Bonds: 5
Polar Surface Area: 68.31 Å2
Index of Refraction: 1.594
Molar Refractivity: 108.51 cm3
Molar Volume: 319.5 cm3
Surface Tension: 51.4 dyne/cm
Density: 1.24 g/cm3
Flash Point: 391.9 °C
Enthalpy of Vaporization: 105.78 kJ/mol
Boiling Point: 724.3 °C at 760 mmHg
Vapour Pressure: 7.79E-21 mmHg at 25°C
Methylaminocolchicide Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 400mg/kg (400mg/kg) | Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 241, Pg. 1889, 1955. | |
| mouse | LD50 | intravenous | 20mg/kg (20mg/kg) | Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 241, Pg. 1889, 1955. |
Methylaminocolchicide Safety Profile
Poison by intravenous and intraperitoneal routes. When Methylaminocolchicide (CAS NO.63917-71-5) is heated to decomposition, it emits toxic fumes of NOx.
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