Toxicity data
(The meaning of any toxicological abbreviations which appear in t
The IUPAC name of Methylthioinosine (CAS NO.342-69-8):
2-(Hydroxymethyl)-5-(6-methylsulfanylpurin-9-yl)oxolane-3,4-diol
Synonyms: Methylthioinosine ; 6-Methylmercaptopurine ribonucleoside ; 6-Methylmercaptopurine riboside ; 6-(Methylthio)-9-beta-d-ribofuranosylpurine ; 6-Methylthiopurine riboside ; 6-Mmpr ; 6-(Methylthio)-9-beta-d-ribofuranosyl-9h-purin ; 6-(Methylthio)-inosin
CAS: 342-69-8
EINECS: 206-442-2
Molecular Formula: C11H14N4O4S
Molecular Structure:
Formula Weight: 298.32 g/mol
Index of Refraction: 1.822
Density: 1.85 g/cm3
Flash Point: 338.6 °C
Boiling Point: 636.3 °C at 760 mmHg
Appearance:White powder.
Air & Water Reactions Slightly soluble in water.
The toxicity of Methylthioinosine (CAS NO.342-69-8):
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD10 | unreported | 20mg/kg (20mg/kg) | Progress in Medical Chemistry. Vol. 7, Pg. 69, 1970. | |
mouse | LD50 | intraperitoneal | 137mg/kg (137mg/kg) | National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986, | |
rat | LD50 | intraperitoneal | 65mg/kg (65mg/kg) | Archives of Pathology. Vol. 86, Pg. 395, 1968. |
NCI Carcinogenesis Studies (ipr); Equivocal Evidence: mouse CANCAR Cancer. 40 (1977),1935. ; (ipr); No Evidence: rat CANCAR Cancer. 40 (1977),1935. .
The Safety Statements of Methylthioinosine (CAS NO.342-69-8):
S22:Do not breathe dust. S24/25:Avoid contact with skin and eyes.
Poison by intraperitoneal route. Experimental teratogenic effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx.
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View