-
Name
Mitonafide
- EINECS
- CAS No. 54824-17-8
- Article Data14
- CAS DataBase
- Density 1.384g/cm3
- Solubility
- Melting Point 138-139 °C(Solv: ethanol (64-17-5))
- Formula C16H15 N3 O4
- Boiling Point 496.8°C at 760 mmHg
- Molecular Weight 349.80
- Flash Point 254.3°C
- Transport Information
- Appearance
- Safety Low toxicity by intraperitoneal route. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and HCl. See also AROMATIC AMINES.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms 3-Nitro-N-(2-dimethylaminoethyl)-1,8-naphthalimide;M 4212; M 4212 (pharmaceutical); Mitonafide; NSC 300288
- PSA 88.13000
- LogP 1.94570
Mitonafide Chemical Properties
Empirical Formula of Mitonafide (CAS NO.54824-17-8): C16H15N3O4
Molecular Weight: 313.308 g/mol
Index of Refraction: 1.667
Density: 1.384 g/cm3
Flash Point: 254.3 °C
Enthalpy of Vaporization: 76.47 kJ/mol
Boiling Point: 496.8 °C at 760 mmHg
Vapour Pressure: 5.22E-10 mmHg at 25 °C
Structure of Mitonafide (CAS NO.54824-17-8):
Mitonafide Toxicity Data With Reference
| 1. | dnd-ham:ovr 10 µmol/L | JJIND8 JNCI, Journal of the National Cancer Institute. 70 (1983),1097. | ||
| 2. | cyt-ham:ovr 1 µmol/L | JJIND8 JNCI, Journal of the National Cancer Institute. 70 (1983),1097. | ||
| 3. | ipr-rat LD50:6500 µg/kg | CCPHDZ Cancer Chemotherapy and Pharmacology. 4 (1980),61. | ||
| 4. | ipr-mus LD50:10,000 µg/kg | CCPHDZ Cancer Chemotherapy and Pharmacology. 4 (1980),61. |
Mitonafide Safety Profile
Low toxicity by intraperitoneal route. Mutation data reported. When heated to decomposition Mitonafide (CAS NO.54824-17-8) emits toxic fumes of NOx and HCl. See also AROMATIC AMINES.
Mitonafide Specification
Mitonafide , its cas register number is 54824-17-8. It also can be called Naphthalimide, 2-(2-(dimethylamino)ethyl)-5-nitro- ; N-(2-(Dimethylamino)ethyl)-3-nitronaphthalimide ; and 2-(2-(Dimethylamino)ethyl)-5-nitro-1H-benz(de)isoquinoline-
1,3(2H)-dione .
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