• Name

  N-[1-(AMINOMETHYL)CYCLOHEXYL]-N,N-DIMETHYLAMINE

• EINECS
• CAS No. 41806-09-1
• Article Data6
• CAS DataBase
• Density g/cm³
• Solubility
• Melting Point
• Formula C₉H₂₂N₂+₂
• Boiling Point 189.3°Cat760mmHg
• Molecular Weight 156.271
• Flash Point 68.8°C
• Transport Information
• Appearance
• Safety
• Risk Codes
• Molecular Structure
• Hazard Symbols
• Synonyms 1-(aminomethyl)-N,N-dimethylcyclohexylamine;1-(aminomethyl)-N,N-dimethylcyclohexanamine;N-[1-(aminomethyl)cyclohexyl]-N,N-dimethylamine;[(aminomethyl)cyclohexyl]dimethylamine;1-Aminomethylcyclohexyldimethylamin;(1-Aminomethyl-cyclohexyl)-dimethyl-amine;1-{1-(dimethylamino)cyclohexyl}methylamine;1-aminomethyl-1-dimethylaminocyclohexane;
• PSA 29.26000
• LogP 1.90990

Synthetic route

16499-30-2

1-(dimethylamino)cyclohexanecarbonitrile

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In diethyl ether; water at 20℃;	92.5%
With lithium aluminium tetrahydride; sulfuric acid In tetrahydrofuran at 40 - 50℃; for 1h;	66%
With lithium aluminium tetrahydride; sulfuric acid In tetrahydrofuran at 0 - 20℃; for 18h;
With lithium aluminium tetrahydride In diethyl ether at 20℃; for 16h;

108-94-1

cyclohexanone

C29H51AlZr

C29H51AlZr

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: H2O / 18 h 2: LiAlH4; H2SO4 / tetrahydrofuran / 18 h / 0 - 20 °C View Scheme

108-94-1

cyclohexanone

1.1'-dinitro-dicyclohexyl

1.1'-dinitro-dicyclohexyl

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 85 percent / H2O / Ambient temperature 2: 66 percent / LiAlH4, H2SO4 / tetrahydrofuran / 1 h / 40 - 50 °C View Scheme

108-94-1

cyclohexanone

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: hydrogenchloride / water / 16 h / 20 °C 2: lithium aluminium tetrahydride / diethyl ether / 16 h / 20 °C View Scheme

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

14588-60-4

4-(benzyloxy)-3,5-dimethoxybenzoic acid

C25H34N2O4*ClH

Conditions

Conditions	Yield
Stage #1: 1-aminomethyl‐1‐cyclohexanedimethylamine; 4-(benzyloxy)-3,5-dimethoxybenzoic acid With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 0 - 20℃; for 24h; Stage #2: With hydrogenchloride In methanol	55.5%

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

150007-96-8

C11H12ClNO5

4-Amino-5-chloro-N-(1-dimethylamino-cyclohexylmethyl)-2-methoxy-benzamide

Conditions

Conditions	Yield
In tetrahydrofuran Ambient temperature;

363626-73-7

4-butoxy-3,5-dimethoxybenzoic acid chloride

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

4-butyloxy-3,5-dimethoxy-N-[(1-dimethylaminocyclohexyl)methyl]benzamide

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

122-01-0

4-chloro-benzoyl chloride

4-Chlorobenzamidomethyl-cyclohexyl dimethylamine

Conditions

Conditions	Yield
In chloroform; water; benzene

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

98-88-4

benzoyl chloride

41804-98-2

1-benzamidomethylcyclohexyldimethylamine hydrochloride

Conditions

Conditions	Yield
With pyridine

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

3535-37-3

3,4-dimethoxybenzoic acid chloride

3,4-dimethoxy benzamidomethyl cyclohexyl dimethylamine hydrochloride

Conditions

Conditions	Yield
In water; benzene

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

609-65-4

o-chlorobenzoyl chloride

A

2-Chlorobenzamidomethyl cyclohexyl dimethylamine hydrochloride

B

41805-04-3

2-chlorobenzamido-methyl-cyclohexyl-dimethylamine hydrochloride

Conditions

Conditions	Yield
In benzene

...Expand

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

3024-72-4

3,4-dichlorobenzoyl chloride

1-(3,4-dichlorobenzamidomethyl)-cyclohexyldimethylamine hydrochloride

Conditions

Conditions	Yield
With pyridine

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

874-60-2

4-methyl-benzoyl chloride

A

4-methylbenzamido methyl cyclohexyl dimethylamine hydrochloride

B

4-Methylbenzamidomethyl-cyclohexyl dimethylamine hydrochloride

Conditions

Conditions	Yield
With triethylamine In water; benzene

...Expand

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

41805-05-4

acetamidomethylcyclohexyl-dimethylamine

Conditions

Conditions	Yield
With sodium hydroxide; acetic anhydride; sodium carbonate

1254057-11-8

4-{[2-(isopropylsulfonyl)phenyl]amino}-2-(methylsulfanyl)-6-oxo-1,6-dihydropyrimidine-5-carboxamide

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

1254046-68-8

2-({[1-(dimethylamino)cyclohexyl]methyl}amino)-4-{[2-(isopropylsulfonyl)phenyl]amino}-6-oxo-1,6-dihydropyrimidine-5-carboxamide

Conditions

Conditions	Yield
In 1-methyl-pyrrolidin-2-one at 180℃; for 0.166667h; Microwave irradiation;

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

1-(3,4-dichlorobenzamidomethyl)-cyclohexylmethylamine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: triethylamine / tetrahydrofuran / 1 h / 20 °C 1.2: 1 h / 20 °C 2.1: diethylazodicarboxylate / toluene / 18 h / 55 °C View Scheme

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

3024-72-4

3,4-dichlorobenzoyl chloride

55154-30-8

AH 7921

Conditions

Conditions	Yield
Stage #1: 1-aminomethyl‐1‐cyclohexanedimethylamine With triethylamine In tetrahydrofuran at 20℃; for 1h; Stage #2: 3,4-dichlorobenzoyl chloride In tetrahydrofuran at 20℃; for 1h;	30.65 g
With triethylamine In diethyl ether at 20℃; for 16h;

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

C6(11)CH3Cl3O

3,4-dichlorobenzene[11C]carboxylic acid (dimethylamino)cyclohexylmethyl amide

Conditions

Conditions	Yield
In tetrahydrofuran Reflux;

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

122-01-0

4-chloro-benzoyl chloride

41805-00-9

4-Chlorbenzamidomethylcyclohexyldimethylamin

Conditions

Conditions	Yield
With triethylamine In diethyl ether at 20℃; for 16h;

41806-09-1

1-aminomethyl‐1‐cyclohexanedimethylamine

329-15-7

4-trifluoromethyl-phenyl acetyl chloride

4-(trifluoromethyl)-N-{[1-(dimethylamino)cyclohexyl]methyl}benzamide

Conditions

Conditions	Yield
With triethylamine In diethyl ether at 20℃; for 16h;

N-[1-(Aminomethyl)cyclohexyl]-n,n-dimethylamine Chemical Properties

The molecular formula of N-[1-(Aminomethyl)cyclohexyl]-n,n-dimethylamine(41806-09-1) is C₉H₂₀N2  and its formula weight is  156.2686.
The chemical synonyms of N-[1-(Aminomethyl)cyclohexyl]-n,n-dimethylamine(41806-09-1) are N-[1-(Aminomethyl)cyclohexyl]-n,n-dimethylamine
The molecular structure of N-[1-(Aminomethyl)cyclohexyl]-n,n-dimethylamine(41806-09-1):