N-(2-Aminoethyl)piperidine

The IUPAC name of N-(2-Aminoethyl)piperidine is 2-piperidin-1-ylethanamine. With the CAS registry number 27578-60-5, it is also named as N-(2-Aminoethyl)piperidine. The product's category is API Intermediates. Besides, it is clear colourless to yellow liquid, which should be stored in closed containers in a cool, dry place. In addition, its molecular formula is C₇H₁₆N₂ and molecular weight is 128.22.

The other characteristics of this product can be summarized as: (1)EINECS: 248-540-8; (2)ACD/LogP: 1.64; (3)# of Rule of 5 Violations: 0; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 2; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 3; (11)Polar Surface Area: 29.26 Å²; (12)Index of Refraction: 1.481; (13)Molar Refractivity: 39.487 cm³; (14)Molar Volume: 138.766 cm³; (15)Polarizability: 15.654×10^-24cm³; (16)Surface Tension: 34.717 dyne/cm; (17)Density: 0.924 g/cm³; (18)Flash Point: 57.778 °C; (19)Enthalpy of Vaporization: 42.222 kJ/mol; (20)Boiling Point: 185.999 °C at 760 mmHg; (21)Vapour Pressure: 0.678 mmHg at 25 °C.

Uses of N-(2-Aminoethyl)piperidine: it can react with 6-chloro-1,3-dimethyl-1H-pyrimidine-2,4-dione to get 1,3-dimethyl-6-[(2-piperidinoethyl)amino]uracil.



This reaction needs Na₂CO₃ by heating for 24 hours. The yield is 68 %.

When you are using this chemical, please be cautious about it as the following: it may cause burns. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. And you should wear suitable protective clothing, gloves and eye/face protection. Moreover, in case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

People can use the following data to convert to the molecule structure.
(1)Canonical SMILES: C1CCN(CC1)CCN
(2)InChI: InChI=1S/C7H16N2/c8-4-7-9-5-2-1-3-6-9/h1-8H2
(3)InChIKey: CJNRGSHEMCMUOE-UHFFFAOYSA-N