N-(Trimethylsilyl)acetamide supplier

Name
N-(Trimethylsilyl)acetamide
EINECS 236-565-7
CAS No. 13435-12-6
Article Data19
CAS DataBase
Density 0.859 g/cm³
Solubility REACTS with water
Melting Point 46-49 °C(lit.)
Formula C5H13 N O Si
Boiling Point 84ºC 18 mm Hg(lit.),190.2 °C at 760 mmHg
Molecular Weight 131.25
Flash Point 70 ºC
Transport Information UN1325
Appearance WHITE TO YELLOWISH CRYSTALLINE MASS
Safety Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of NO_x.
Risk Codes R11;R36/37/38
Molecular Structure
Hazard Symbols
Synonyms (Acetylamino)trimethylsilane;N-(Trimethylsilyl)acetamide; NSC 139859; Trimethylsilyl acetamide
PSA 29.10000
LogP 1.34830

N-(Trimethylsilyl)acetamide Chemical Properties

Chemistry informtion about N-Trimethylsilylacetamide (CAS NO.13435-12-6) is:
IUPAC Name: N-Trimethylsilylacetamide
Synonyms: (Acetylamino)Trimethylsilane ; N-(Trimethylsilyl)-Acetamid ; N-Trimethylsilylacetamide ; Trimethylsilylacetamide ; Tmsa ; Tms Acetamide ; N-Trimethylsilylacetamidea.R. ; Acetamide, N-(Trimethylsilyl)-
MF: C₅H₁₃NOSi
MW: 131.25
EINECS: 236-565-7
Density: 0.859 g/cm³
Melting Point: 46-49 °C(lit.)
Flash Point: 44.1 °C
Boiling Point: 190.2 °C at 760 mmHg
Vapour Pressure: 0.548 mmHg at 25°C
Enthalpy of Vaporization: 42.64 kJ/mol
Storage temp.: Flammables area
Sensitive Moisture: Sensitive
BRN: 741928
Product Categories: Analytical Chemistry ; GC Derivatizing Reagents ; Si (Classes of Silicon Compounds) ; Silicon Compounds (for Synthesis) ; Silylacetamides ; Silylation (GC Derivatizing Reagents) ; Si-N Compounds ; Synthetic Organic Chemistry ; Trimethylsilylation (GC Derivatizing Reagents)
Following is the molecular structure of N-Trimethylsilylacetamide (CAS NO.13435-12-6) is:

N-(Trimethylsilyl)acetamide Production

Its preparation products is cefdinir .

N-(Trimethylsilyl)acetamide Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LDLo	intraperitoneal	350mg/kg (350mg/kg)	immunological including allergic: decreased immune response	Personal Communication from G.D. Stoner, Dept. of Community Medicine, School of Medicine, Univ. of California, La Jolla, CA 92037, May 25, 1975Vol. 27MAY1975,

N-(Trimethylsilyl)acetamide Consensus Reports

Reported in EPA TSCA Inventory.

N-(Trimethylsilyl)acetamide Safety Profile

Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes:
Irritant Xi
F
Risk Statements:
R36/37/38:Irritating to eyes, respiratory system and skin.
R11:Highly flammable.
Safety Statements:
S37/39:Wear suitable gloves and eye/face protection.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR: 1325
WGK Germany:3
RTECS: AD0250000
F:
F 10: Keep under argon.
F 21: Sensitive to humidity.
TSCA: Yes
HazardClass: 4.1
PackingGroup: III

N-(Trimethylsilyl)acetamide Specification

N-Trimethylsilylacetamide (CAS NO.13435-12-6) is a white to yellowish crystalline mass.
First Aid Measures:
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Get medical aid. Wash mouth out with water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.
Handling and Storage:
Handling: Use spark-proof tools and explosion proof equipment. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage: Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Flammables-area.

Product Name

N-(Trimethylsilyl)acetamide