Product Name

  • Name

    N-Cbz-L-histidine

  • EINECS 239-084-0
  • CAS No. 14997-58-1
  • Article Data18
  • CAS DataBase
  • Density 1.368 g/cm3
  • Solubility almost transparency
  • Melting Point 168 °C (dec.)(lit.)
  • Formula C14H15N3O4
  • Boiling Point 616.7 °C at 760 mmHg
  • Molecular Weight 289.291
  • Flash Point 326.8 °C
  • Transport Information
  • Appearance White to off-white microcrystalline powder
  • Safety 22-24/25-36-26
  • Risk Codes 20/21/22-36/37/38
  • Molecular Structure Molecular Structure of 14997-58-1 (N-Cbz-L-histidine)
  • Hazard Symbols HarmfulXn
  • Synonyms Histidine,N-carboxy-, N-benzyl ester, L- (8CI);(Benzyloxycarbonyl)histidine;N-(Benzyloxycarbonyl)-L-histidine;N-(Benzyloxycarbonyl)-S-histidine;N-Carbobenzoxy-L-histidine;N-Carbobenzoxyhistidine;Na-(Benzyloxycarbonyl)histidine;Z-His-OH;
  • PSA 104.31000
  • LogP 1.72270

N-Cbz-L-histidine Chemical Properties


IUPAC Name: 3-(1H-Imidazol-5-yl)-2-(phenylmethoxycarbonylamino)propanoic acid
Molecular Formula: C14H15N3O4
Molecular Weight:  289.29
EINECS: 239-084-0
Appearance: White powder
Storage: Tightly closed, store in cool, dry place
Product Categories: Amino Acid Derivatives; Histidine [His, H]; Z-Amino Acids and Derivatives; Cbz-Amino Acids; Amino Acids; Amino Acids (N-Protected); Biochemistry; Z-Amino acid series Melting Point: 168 °C (dec.)(lit.)
alpha: -24 °(c=1 in 6 M HCl)
refractive index: -23.5 ° (C=6, 6mol/L HCl)
storage temp.: -20 °C
Index of Refraction: 1.613 
Molar Refractivity: 73.6 cm3 
Molar Volume: 211.3 cm3 
Surface Tension: 65.4 dyne/cm 
Density: 1.368 g/cm3 
Flash Point: 326.8 °C 
Enthalpy of Vaporization: 96.16 kJ/mol 
Boiling Point: 616.7 °C at 760 mmHg
Vapour Pressure of Z-His-OH (CAS NO.14997-58-1): 4.56E-16 mmHg at 25 °C

N-Cbz-L-histidine Safety Profile

Hazard Codes: HarmfulXn
Risk Statements: 20/21/22-36/37/38 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-36-26 
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
WGK Germany of Z-His-OH (CAS NO.14997-58-1): 3

N-Cbz-L-histidine Specification

  Z-His-OH (CAS NO.14997-58-1), its Synonyms are N-Benzyloxycarbonyl-L-histidine ; (S)-2-Benzyloxycarbonylamino-3-(3H-imidazol-4-yl)propionic acid ; Cbz-L-His-OH .

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