N-Glycyl-L-leucine

The L-Leucine, glycyl-, with the CAS registry number 869-19-2, is also known as Gly-Leu and N-Glycyl-L-leucine. It belongs to the product categories of Amino Acids 13C, 2H, 15N; Biochemistry; Oligopeptides; Peptide Synthesis; Amino Acid Derivatives and Amino Acids & Derivatives. Its EINECS registry number is 212-785-9. This chemical's molecular formula is C₈H₁₆N₂O₃ and molecular weight is 188.23. What's more, its IUPAC name is (2S)-2-[(2-Aminoacetyl)amino]-4-methylpentanoic acid and systematic name is called Glycyl-L-leucine.It is white solid.

Physical properties about L-Leucine, glycyl- are: (1) ACD/LogP: -0.09; (2) # of Rule of 5 Violations: 0; (3) ACD/LogD (pH 5.5): -2.59; (4) ACD/LogD (pH 7.4): -2.82; (5) ACD/BCF (pH 5.5): 1; (6) ACD/BCF (pH 7.4): 1; (7) ACD/KOC (pH 5.5): 1; (8) ACD/KOC (pH 7.4): 1; (9) #H bond acceptors: 5; (10) #H bond donors: 4; (11) #Freely Rotating Bonds: 6; (12) Polar Surface Area: 49.85 Å²; (13) Index of Refraction: 1.488; (14) Molar Refractivity: 47.75 cm³; (15) Molar Volume: 165.5 cm³; (16) Surface Tension: 45 dyne/cm; (17) Density: 1.136 g/cm³; (18) Flash Point: 202 °C; (19) Enthalpy of Vaporization: 72.71 kJ/mol; (20) Boiling Point: 410.4 °C at 760 mmHg; (21) Vapour Pressure: 6.97E-08 mmHg at 25 °C; (22) Melting Point: 233-235 °C.

Uses of L-Leucine, glycyl-: (1) it is used as substrate for the assay of Glycyl-L-leucine dipeptidase; (2) it is used to produce other chemicals. For example, it is used to produce Beoc-Gly-L-Leu.



The reaction occurs with reagent NaOH and at ambient temperature for 18 hours. The yield is 96.1 %.

When you are dealing with this chemical, you should be very careful. You must avoid contacting with skin and eyes.

You can still convert the following datas into molecular structure:
(1) SMILES: O=C(N[C@H](C(=O)O)CC(C)C)CN
(2) InChI: InChI=1/C8H16N2O3/c1-5(2)3-6(8(12)13)10-7(11)4-9/h5-6H,3-4,9H2,1-2H3,(H,10,11)(H,12,13)/t6-/m0/s1
(3) InChIKey: DKEXFJVMVGETOO-LURJTMIEBJ