Product Name

  • Name

    N-hydroxyphenacetin

  • EINECS
  • CAS No. 19315-64-1
  • Article Data5
  • CAS DataBase
  • Density 1.2g/cm3
  • Solubility
  • Melting Point
  • Formula C10H13 N O3
  • Boiling Point 345.5°Cat760mmHg
  • Molecular Weight 195.218
  • Flash Point 162.7°C
  • Transport Information
  • Appearance
  • Safety Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 19315-64-1 (N-hydroxyphenacetin)
  • Hazard Symbols
  • Synonyms Acetohydroxamicacid, N-(p-ethoxyphenyl)- (8CI); 4'-Ethoxy-N-hydroxyacetanilide;N-(4-Ethoxyphenyl)-N-hydroxyacetamide; N-Hydroxy-p-acetophenetidide;N-Hydroxyphenacetin; NSC 229647
  • PSA 49.77000
  • LogP 1.82740

N-Hydroxyphenacetin Chemical Properties

Empirical Formula of N-Hydroxyphenacetin (CAS NO.19315-64-1): C10H13NO3
Molecular Weight: 195.2151 
Index of Refraction: 1.571
Density: 1.2 g/cm3
Flash Point: 162.7 °C
Enthalpy of Vaporization: 62.22 kJ/mol
Boiling Point: 345.5 °C at 760 mmHg
Vapour Pressure: 2.33E-05 mmHg at 25 °C
Structure of N-Hydroxyphenacetin (CAS NO.19315-64-1):
                       
IUPAC Name: N-(4-Ethoxyphenyl)-N-hydroxyacetamide
Canonical SMILES: CCOC1=CC=C(C=C1)N(C(=O)C)O
InChI: InChI=1S/C10H13NO3/c1-3-14-10-6-4-9(5-7-10)11(13)8(2)12/h4-7,13H,3H2,1-2H3
InChIKey: GPMYDZBSYQUDJZ-UHFFFAOYSA-N

N-Hydroxyphenacetin Toxicity Data With Reference

1.    

mma-sat 500 µg/plate

     MUREAV    Mutation Research. 58 (1978),387.
2.    

otr-mus:emb 100 µg/L

     NCIMAV    National Cancer Institute, Monograph. 58 (1981),21.
3.    

ipr-mus LD50:702 mg/kg

     ARTODN    Archives of Toxicology. 56 (1984),96.

N-Hydroxyphenacetin Consensus Reports

IARC Cancer Review: Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 13 , 1977,p. 141.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 24 , 1980,p. 135.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .

N-Hydroxyphenacetin Safety Profile

Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition N-Hydroxyphenacetin (CAS NO.19315-64-1) emits toxic fumes of NOx.

N-Hydroxyphenacetin Specification

 N-Hydroxyphenacetin , its cas register number is 19315-64-1. It also can be called Acetohydroxamic acid, N-(4-ethoxyphenyl)- ; p-Acetophenetidide, N-hydroxy- ; Acetohydroxamic acid, N-(p-ethoxyphenyl)- (8CI) ; and N-Hydroxy-p-acetophenetidide .

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