Product Name

  • Name

    tolciclate

  • EINECS
  • CAS No. 50838-36-3
  • Article Data3
  • CAS DataBase
  • Density 1.231g/cm3
  • Solubility
  • Melting Point 92-94°
  • Formula C20H21NOS
  • Boiling Point 447.3°Cat760mmHg
  • Molecular Weight 323.459
  • Flash Point 224.3°C
  • Transport Information
  • Appearance
  • Safety Poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also ESTERS and CARBAMATES.
  • Risk Codes
  • Molecular Structure Molecular Structure of 50838-36-3 (tolciclate)
  • Hazard Symbols
  • Synonyms Tolciclato;KC 9147;Tolciclatum;Tolciclato [DCIT];EINECS 256-792-5;K 9147;Tolciclatum [INN-Latin];Tolmicen;
  • PSA 44.56000
  • LogP 5.15980

N-MethyL-N-(m-tolyl)carbamothioic acid-(1,2,3,4-tetrahydro-1,4-methano-naphthalen-6-yl) ester Chemical Properties

Product Name: N-MethyL-N-(m-tolyl)carbamothioic acid-(1,2,3,4-tetrahydro-1,4-methano-naphthalen-6-yl) ester   
Synonyms of N-MethyL-N-(m-tolyl)carbamothioic acid-(1,2,3,4-tetrahydro-1,4-methano-naphthalen-6-yl) ester (CAS NO.50838-36-3) : Carbamothioic acid, N-methyl-N-(3-methylphenyl)-, O-(1,2,3,4-tetrahydro-1,4-methanonaphthalen-6-yl) ester ; Fungifos ; Methyl(3-methylphenyl)carbamothioic Acid O-(1,2,3,4-Tetrahydro-1,4-methanonaphthalen-6-yl) Ester ; O-(1,4-Methano-1,2,3,4-tetrahydro-6-naphthyl)-N-methyl-N-(m-tolyl)thiocarbamate ; O-Tricyclo[6.2.1.0~2,7~]undeca-2,4,6-trien-4-yl methyl(3-methylphenyl)carbamothioate ; Tolmicen
CAS NO: 50838-36-3   
Molecular Formula:C20H21NOS                              
Molecular Weight :323.4518                                       
Molecular Structure :
EINECS: 256-792-5
Index of Refraction: 1.672   
Surface Tension: 56.6 dyne/cm 
Density: 1.231 g/cm3 
Flash Point: 224.3 °C 
Enthalpy of Vaporization: 70.56 kJ/mol 
Boiling Point: 447.3 °C at 760 mmHg 
Vapour Pressure: 3.41E-08 mmHg at 25°C 

N-MethyL-N-(m-tolyl)carbamothioic acid-(1,2,3,4-tetrahydro-1,4-methano-naphthalen-6-yl) ester Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 124mg/kg (124mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

GASTROINTESTINAL: NAUSEA OR VOMITING		 Kiso to Rinsho. Clinical Report. Vol. 15, Pg. 2399, 1981.
dog LD50 oral 5gm/kg (5000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 769, 1976.
mouse LD50 intraperitoneal > 420mg/kg (420mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 15, Pg. 2399, 1981.
mouse LD50 intravenous 80200ug/kg (80.2mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Kiso to Rinsho. Clinical Report. Vol. 15, Pg. 2399, 1981.
mouse LD50 oral > 1800mg/kg (1800mg/kg)   Drugs in Japan Vol. -, Pg. 881, 1995.
mouse LD50 subcutaneous > 420mg/kg (420mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 15, Pg. 2399, 1981.
rabbit LD50 intravenous 94800ug/kg (94.8mg/kg) SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)		 Kiso to Rinsho. Clinical Report. Vol. 15, Pg. 2399, 1981.
rabbit LD50 oral > 1gm/kg (1000mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 15, Pg. 2399, 1981.
rat LD50 intraperitoneal > 420mg/kg (420mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 15, Pg. 2399, 1981.
rat LD50 intravenous 151mg/kg (151mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Kiso to Rinsho. Clinical Report. Vol. 15, Pg. 2399, 1981.
rat LD50 oral > 1800mg/kg (1800mg/kg)   Drugs in Japan Vol. -, Pg. 881, 1995.
rat LD50 subcutaneous > 1gm/kg (1000mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 15, Pg. 2399, 1981.

 

N-MethyL-N-(m-tolyl)carbamothioic acid-(1,2,3,4-tetrahydro-1,4-methano-naphthalen-6-yl) ester Safety Profile

 N-MethyL-N-(m-tolyl)carbamothioic acid-(1,2,3,4-tetrahydro-1,4-methano-naphthalen-6-yl) ester (CAS NO.50838-36-3) is poisonous by intravenous route. Moderately toxic by ingestion. When N-MethyL-N-(m-tolyl)carbamothioic acid-(1,2,3,4-tetrahydro-1,4-methano-naphthalen-6-yl) ester (CAS NO.50838-36-3)  is heated to decomposition ,it emits very toxic fumes of NOx and SOx. See also ESTERS and CARBAMATES.

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