-
Name
2-fluoro-N-methyl-N-naphthalen-1-yl-acetamide
- EINECS
- CAS No. 5903-13-9
- Density 1.202g/cm3
- Solubility
- Melting Point
- Formula C13H12 F N O
- Boiling Point 346.8°Cat760mmHg
- Molecular Weight 217.243
- Flash Point 163.5°C
- Transport Information
- Appearance
- Safety Poison by ingestion, skin contact, subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of F− and NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms Acetamide,2-fluoro-N-methyl-N-1-naphthyl- (7CI,8CI);2-Fluoro-N-methyl-N-(1-naphthenyl)acetamide; 2-Fluoro-N-methyl-N-1-naphthylacetamide;DP X 1410; MNFA; N-Methyl-N-(1-naphthyl)fluoroacetamide;N-Methyl-N-(1-naphthyl)monofluoroacetamide;N-Methyl-N-1-naphthyl-2-fluoro-acetamide; Nissol; Nissol EC
- PSA 20.31000
- LogP 2.77210
N-Methyl-n-(1-naphthyl)fluoro-acetamide Chemical Properties
IUPAC Name: 2-Fluoro-N-methyl-N-naphthalen-1-ylacetamide
Synonyms: 2-Fluor-N-methyl-N-(1-naphthyl)acetamid ; 2-Fluoro-N-methyl-N-(1-naphthalenyl)acetamide ; 2-Fluoro-N-methyl-N-(1-naphthyl)acetamide ; 2-Fluoro-N-méthyl-N-(1-naphtyl)acétamide ; Acetamide, 2-fluoro-N-methyl-N-1-naphthalenyl- ; MNAF
CAS NO:5903-13-9
Molecular Formula of N-Methyl-n-(1-naphthyl)fluoro-acetamide (CAS NO.5903-13-9) :C13H12FNO
Molecular Weight of N-Methyl-n-(1-naphthyl)fluoro-acetamide (CAS NO.5903-13-9) :217.2389
Molecular Structure of N-Methyl-n-(1-naphthyl)fluoro-acetamide (CAS NO.5903-13-9) :
Index of Refraction: 1.617
Surface Tension: 44.8 dyne/cm
Density: 1.202 g/cm3
Flash Point: 163.5 °C
Enthalpy of Vaporization: 59.1 kJ/mol
Boiling Point: 346.8 °C at 760 mmHg
Vapour Pressure: 5.62E-05 mmHg at 25°C
N-Methyl-n-(1-naphthyl)fluoro-acetamide Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| cat | LD50 | oral | 2500ug/kg (2.5mg/kg) | Experimental Animals. Jikken Dobutso Iho. Vol. 21, Pg. 88, 1972. | |
| cat | LD50 | skin | 4mg/kg (4mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 65, Pg. 182, 1969. |
| chicken | LDLo | oral | 50mg/kg (50mg/kg) | Toxicology and Applied Pharmacology. Vol. 12, Pg. 536, 1968. | |
| dog | LD50 | oral | 2mg/kg (2mg/kg) | Experimental Animals. Jikken Dobutso Iho. Vol. 21, Pg. 88, 1972. | |
| dog | LD50 | skin | 2750ug/kg (2.75mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 65, Pg. 182, 1969. |
| dog | LDLo | intraperitoneal | 2mg/kg (2mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT CARDIAC: CARDIOMYOPATHY INCLUDING INFARCTION | Toxicology and Applied Pharmacology. Vol. 12, Pg. 536, 1968. |
| guinea pig | LD50 | oral | 500ug/kg (0.5mg/kg) | Experimental Animals. Jikken Dobutso Iho. Vol. 21, Pg. 88, 1972. | |
| guinea pig | LD50 | skin | 5mg/kg (5mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Toxicology and Applied Pharmacology. Vol. 12, Pg. 536, 1968. |
| guinea pig | LDLo | subcutaneous | 1mg/kg (1mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Toxicology and Applied Pharmacology. Vol. 12, Pg. 536, 1968. |
| monkey | LD50 | oral | 300mg/kg (300mg/kg) | "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976. | |
| monkey | LDLo | intraperitoneal | 100mg/kg (100mg/kg) | BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Toxicology and Applied Pharmacology. Vol. 12, Pg. 536, 1968. |
| monkey | LDLo | skin | 800mg/kg (800mg/kg) | BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Toxicology and Applied Pharmacology. Vol. 12, Pg. 536, 1968. |
| monkey | LDLo | subcutaneous | 150mg/kg (150mg/kg) | BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING | Toxicology and Applied Pharmacology. Vol. 12, Pg. 536, 1968. |
| mouse | LD50 | intraperitoneal | 164mg/kg (164mg/kg) | BEHAVIORAL: EXCITEMENT BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Toxicology and Applied Pharmacology. Vol. 12, Pg. 536, 1968. |
| mouse | LD50 | oral | 200mg/kg (200mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 463, 1970. | |
| mouse | LD50 | skin | 370mg/kg (370mg/kg) | Experimental Animals. Jikken Dobutso Iho. Vol. 21, Pg. 88, 1972. | |
| mouse | LD50 | subcutaneous | 216mg/kg (216mg/kg) | BEHAVIORAL: EXCITEMENT BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Toxicology and Applied Pharmacology. Vol. 12, Pg. 536, 1968. |
| rabbit | LD50 | oral | 1500ug/kg (1.5mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Experimental Animals. Jikken Dobutso Iho. Vol. 21, Pg. 88, 1972. |
| rabbit | LD50 | skin | 1750ug/kg (1.75mg/kg) | Experimental Animals. Jikken Dobutso Iho. Vol. 21, Pg. 88, 1972. | |
| rabbit | LDLo | intravenous | 5mg/kg (5mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Toxicology and Applied Pharmacology. Vol. 12, Pg. 536, 1968. |
| rat | LD50 | oral | 67mg/kg (67mg/kg) | Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 9, Pg. 563, 1967. | |
| rat | LD50 | skin | 213mg/kg (213mg/kg) | World Review of Pest Control. Vol. 9, Pg. 119, 1970. | |
| rat | LD50 | subcutaneous | 41mg/kg (41mg/kg) | BEHAVIORAL: EXCITEMENT BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Toxicology and Applied Pharmacology. Vol. 12, Pg. 536, 1968. |
N-Methyl-n-(1-naphthyl)fluoro-acetamide Safety Profile
Poison by ingestion, skin contact, subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of F− and NOx.
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