Product Name: n-Nitrosobis(2-oxopropyl)amine (60599-38-4)
Molecular Formula: C6H10N2O3
Molecular Weight: 158.18g/mol
Mol File: 60599-38-4.mol
Melting Point: 136 °C
Boiling point: 315.8 °C at 760 mmHg
Flash Point: 144.8 °C
Density: 1.17 g/cm3
Synonyms of n-Nitrosobis(2-oxopropyl)amine (60599-38-4): 2,2'-Dioxo-di-n-propylnitrosamine ; 2,2'-Dioxopropyl-N-propylnitrosamine ; Acetone, (nitrosoimino)di- ; BOP ; BRN 2245698 ; Bis-(2-oxopropyl)-N-nitrosamine ; CCRIS 460 ; Di-oxo-di-n-propylnitrosamine ; N,N-Di(2-oxopropyl)nitrosamine ; N-Nitroso-N,N-di(2-oxypropyl)amine ; N-Nitrosobis(2-oxopropyl)amine ; Nitrosobis(2-oxopropyl)amine .
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | subcutaneous | 205mg/kg (205mg/kg) | VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA | Cancer Letters Vol. 5, Pg. 31, 1978. |
hamster | LD50 | oral | 142mg/kg (142mg/kg) | Cancer Letters Vol. 2, Pg. 323, 1977. | |
hamster | LD50 | subcutaneous | 89mg/kg (89mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES KIDNEY, URETER, AND BLADDER: "INFLAMMATION, NECROSIS, OR SCARRING OF BLADDER" LIVER: OTHER CHANGES | Journal of the National Cancer Institute. Vol. 58, Pg. 1449, 1977. |
rat | LD50 | subcutaneous | 100mg/kg (100mg/kg) | Cancer Letters Vol. 5, Pg. 13, 1978. |
Suspected carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic data. Poison by ingestion and subcutaneous routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
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