Product Name

  • Name

    NOVOBIOCIN SODIUM SALT

  • EINECS
  • CAS No. 1476-53-5
  • Density 1.42g/cm3
  • Solubility Soluble in water at 100mg/ml. Also soluble in ethanol or DMSOSoluble in water, ethanol, dimethyldulfoxide and methanol.
  • Melting Point 215-220oC
  • Formula C31H36 N2 O11 . Na
  • Boiling Point 848.2°Cat760mmHg
  • Molecular Weight 634.615
  • Flash Point 466.8°C
  • Transport Information
  • Appearance
  • Safety Poison by intraperitoneal and subcutaneous routes. Moderately toxic by ingestion. Mutation data reported. An antibiotic with serious side effects which include liver and blood disease. It may also promote the development of resistant strains of staphylococcus. When heated to decomposition it emits toxic fumes of NOx and Na2O.
  • Risk Codes 43-36
  • Molecular Structure Molecular Structure of 1476-53-5 (NOVOBIOCIN SODIUM SALT)
  • Hazard Symbols
  • Synonyms Benzamide,N-[7-[[3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-a-L-lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-hydroxy-3-(3-methyl-2-butenyl)-,monosodium salt (9CI); Novobiocin, monosodium salt (8CI); Novobiocin, sodiumderiv. (6CI,7CI); Albamycin; Albamycin (capsule); Albamycin sodium; Cathomycinsodium; Cathomycin sodium lyovac; Monosodium novobiocin; NSC 2382; Novobiocinmonosodium; Novobiocin sodium; Novobiocin sodium salt; Sodium albamycin; Sodiumnovobiocin; Vulcamycin
  • PSA 202.84000
  • LogP 4.83860

NOVOBIOCIN, MONOSODIUM SALT Chemical Properties

Product Name:  Novobiocin, monosodium salt  (1476-53-5)


Molecular Formula: C31H35N2NaO11
Molecular Weight: 634.61g/mol
Mol File: 1476-53-5.mol
Einecs: 216-023-6
Melting Point: 215-220 °C
Boiling point: 848.2°C at 760mmHg
Storage Temperature: 2-8°C
Flash Point: 466.8°C
Density: 1.42g/cm3
Product Categories: Coumarin-glycosidesAntibiotics ; Antibacterial ; Antibiotics ; Antibiotics A to ; Antibiotics by Application ; Antibiotics N-SAntibiotics ; Antineoplastic and Immunosuppressive AntibioticsAntibiotics ; Chemical Structure Class ; Inhibits an EnzymeAntibiotics ; Interferes with DNA SynthesisSpectrum of Activity ; L - ZMore...Close...; Mechanism of Action
Synonyms of Novobiocin, monosodium salt (1476-53-5): albamycin(capsule) ; Albamycinsodium ; Cathomycinsodium ; Cathomycinsodiumlyovac ; Monosodiumnovobiocin ; Novobiocin,sodiumderiv. ; Novobiocinmonosodium ; Sodiumalbamycin.

NOVOBIOCIN, MONOSODIUM SALT Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intraperitoneal 12mg/kg (12mg/kg)   "Compounds Available for Fundamental Research, Volume II-6, Antibiotics, A Program of Upjohn Company Research Laboratory." Vol. 2(6), Pg. -, 1971.
guinea pig LD50 subcutaneous 28mg/kg (28mg/kg)   "Compounds Available for Fundamental Research, Volume II-6, Antibiotics, A Program of Upjohn Company Research Laboratory." Vol. 2(6), Pg. -, 1971.
mouse LD50 intraperitoneal 262mg/kg (262mg/kg)   Antibiotics and Chemotherapy Vol. 6, Pg. 226, 1956.
mouse LD50 intravenous 407mg/kg (407mg/kg)   Antibiotics and Chemotherapy Vol. 6, Pg. 226, 1956.
mouse LD50 oral 962mg/kg (962mg/kg)   Antibiotics and Chemotherapy Vol. 6, Pg. 226, 1956.
mouse LD50 subcutaneous 395mg/kg (395mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 386, 1958.
rat LD50 intravenous 385mg/kg (385mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 386, 1958.
rat LD50 oral 3500mg/kg (3500mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 386, 1958.
rat LD50 subcutaneous 450mg/kg (450mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 386, 1958.

NOVOBIOCIN, MONOSODIUM SALT Safety Profile

Poison by intraperitoneal and subcutaneous routes. Moderately toxic by ingestion. Mutation data reported. An antibiotic with serious side effects which include liver and blood disease. It may also promote the development of resistant strains of staphylococcus. When heated to decomposition it emits toxic fumes of NOx and Na2O.
Safety Information of Novobiocin, monosodium salt (1476-53-5):
Hazard Codes: Xi,Xn
Risk Statements: 43-36-36/37/38-20/21/22 
20:  Harmful by inhalation 
21:  Harmful in contact with skin 
22:  Harmful if swallowed 
36:  Irritating to the eyes 
37:  Irritating to the respiratory system 
38:  Irritating to the skin 
43:  May cause sensitization by skin contact 
Safety Statements: 36-36/37-26-37/39
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36:  Wear suitable protective clothing 
37:  Wear suitable gloves  
39:  Wear eye/face protection

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