-
Name
Naftypramide
- EINECS
- CAS No. 1505-95-9
- Density 1.061g/cm3
- Solubility
- Melting Point
- Formula C19H26 N2 O
- Boiling Point 482.6°Cat760mmHg
- Molecular Weight 298.428
- Flash Point 245.7°C
- Transport Information
- Appearance
- Safety Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms 1-Naphthaleneacetamide,a-[2-(dimethylamino)ethyl]-a-isopropyl- (7CI,8CI); DA 992;Naftipramide; Naftypramide; Naphthipramide; Naphthypramide; a-Isopropyl-a-(2-dimethylaminoethyl)-1-naphthacetamide;a-Isopropyl-a-(2-dimethylaminoethyl)-1-naphthylacetamide;a-Isopropyl-a-[2-(dimethylamino)ethyl]-1-naphthaleneacetamide;a-Isopropyl-a-dimethylaminoethyl-1-naphthylacetamide;a-[2-(Dimethylamino)ethyl]-a-(1-methylethyl)-1-naphthaleneacetamide
- PSA 46.33000
- LogP 3.87090
Naftypramide Chemical Properties
Empirical Formula of Naftypramide (CAS NO.1505-95-9): C19H26N2O
Molecular Weight: 298.4225 g/mol
Index of Refraction: 1.574
Density: 1.061 g/cm3
Flash Point: 245.7 °C
Enthalpy of Vaporization: 74.75 kJ/mol
Boiling Point: 482.6 °C at 760 mmHg
Vapour Pressure: 1.8E-09 mmHg at 25 °C
Structure of Naftypramide (CAS NO.1505-95-9):
.png)
IUPAC Name: 2-(2-Dimethylaminoethyl)-3-methyl-2-naphthalen-1-ylbutanamide
Naftypramide Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LDLo | oral | > 500mg/kg (500mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION GASTROINTESTINAL: NAUSEA OR VOMITING | Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 356, 1968. |
| mouse | LD50 | intravenous | 72mg/kg (72mg/kg) | Experientia. Vol. 20, Pg. 457, 1964. | |
| mouse | LD50 | oral | 1086mg/kg (1086mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 162, Pg. 378, 1966. | |
| mouse | LDLo | intraperitoneal | 250mg/kg (250mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) | Journal of Medicinal Chemistry. Vol. 8, Pg. 594, 1965. |
| rat | LD50 | intraperitoneal | 269mg/kg (269mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 162, Pg. 378, 1966. | |
| rat | LD50 | oral | 1030mg/kg (1030mg/kg) | Journal of Medicinal Chemistry. Vol. 16, Pg. 720, 1973. |
Naftypramide Safety Profile
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. When heated to decomposition Naftypramide (CAS NO.1505-95-9) emits toxic fumes of NOx.
Naftypramide Specification
Naftypramide ,its cas register number is 1505-95-9. It also can be called 4-Dimethylamino-2-isopropyl-2-(1-naphtyl)butyramid ; and 1-Naphthaleneacetamide, alpha-(2-(dimethylamino)ethyl)-alpha-isopropyl- .
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View