Product Name

  • Name

    Naltrexone

  • EINECS 240-649-9
  • CAS No. 16590-41-3
  • Article Data46
  • CAS DataBase
  • Density 1.47g/cm3
  • Solubility
  • Melting Point 168-170°
  • Formula C20H23 N O4
  • Boiling Point 558.1°C at 760 mmHg
  • Molecular Weight 341.407
  • Flash Point 291.4°C
  • Transport Information
  • Appearance Crystals from acetone.
  • Safety Moderately toxic by subcutaneous route. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also (−)-MORPHINE and KETONES.
  • Risk Codes 11-23/24/25-39/23/24/25
  • Molecular Structure Molecular Structure of 16590-41-3 (Naltrexone)
  • Hazard Symbols F,T
  • Synonyms Morphinan-6-one,17-(cyclopropylmethyl)-4,5a-epoxy-3,14-dihydroxy- (8CI); 1-N-Cyclopropylmethyl-7,8-dihydro-14-hydroxynormorphinone;Depotrex; EN 1639; N-Cyclopropylmethylnoroxymorphone; Naltrel; Naltrexone;Nemexin; ReVia; Trexonil; UM 792; Vivitrex; Vivitrol
  • PSA 70.00000
  • LogP 1.46330

Naltrexone Chemical Properties

Synonyms: 17-(cyclopropylmethyl)-4,5-alpha-epoxy-3,14-dihydroxy-morphinan-6-on;17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one;5-epoxy-3,14-dihydroxy-17-(cyclopropylmethyl)-(5-alpha)-morphinan-6-on;celupan;en1639;en1939;n-cyclopropylmethyl-14-hydroxydihydromorphinone;
MF: C20H23NO4
MW: 341.4
EINECS: 240-649-9

Naltrexone Toxicity Data With Reference

N-CYCLOPROPYLMETHYLNOROXY-MORPHONE's toxicity information:

1.

   

sce-hmn:lym 1 g/L

   ENMUDM    Environmental Mutagenesis. 1 (1979),180.
2.   

cyt-hmn:lym 1 g/L

   ENMUDM    Environmental Mutagenesis. 1 (1979),180.
3.   

sln-dmg-orl 10 g/L/24H

   MUREAV    Mutation Research. 66 (1979),129.
4.   

sln-dmg-par 10 g/L

   MUREAV    Mutation Research. 66 (1979),129.
5.   

scu-mus LD50:551 mg/kg

   ANYAA9    Annals of the New York Academy of Sciences. 281 (1976),321.

Naltrexone Consensus Reports

EPA Genetic Toxicology Program.

Naltrexone Safety Profile

Moderately toxic by subcutaneous route. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also (−)-MORPHINE and KETONES.

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