Neomycin B supplier | CasNO.119-04-0

Name
NEOMYCIN B
EINECS 204-292-2
CAS No. 119-04-0
Article Data4
CAS DataBase
Density 1.61 g/cm³
Solubility
Melting Point
Formula C23H46 N6 O13
Boiling Point 927.1 °C at 760 mmHg
Molecular Weight 614.651
Flash Point 514.5 °C
Transport Information
Appearance Clear Liquid
Safety Poison by intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x.
Risk Codes 42/43
Molecular Structure
Hazard Symbols Xn
Synonyms 5)]-2-deoxy-;Neomycin B (8CI);Actilin;Actiline;Antibiotic 10676;Antibiotique EF 185;Dekamycin III;Enterfram;Fradiomycin B;Framidal;Framycetin;Framycin;Framygen;Francetin;Fraquinol;Leo Red Dry Cow;
PSA 353.11000
LogP -4.69350

Neomycin B Chemical Properties

Chemistry informtion about Neomycin B (CAS NO.119-04-0) is:
IUPAC Name: (2r,3s,4r,5r,6r)-5-Amino-2-(Aminomethyl)-6-[(1r,2r,3s,4r,6s)-4,6-Diamino-2-[(2s,3r,4s,5r)-4-[(2r,3r,4r,5s,6s)-3-Amino-6-(Aminomethyl)-4,5-Dihydroxyoxan-2-Yl]Oxy-3-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Oxy-3-Hydroxycyclohexyl]Oxyoxane-3,4-Diol
Synonyms: Neomycin Standard ; Neomycin B ; Actilin ; Actiline ; Antibiotique ; Enterfram ; Framycetin ; Framygen
Product Categories: L - ZAlphabetic ; NA - NIMore...Close... ; AminoglycosidesAntibiotics ; Antibacterial ; Antibiotics ; Antibiotics A to ; Antibiotics by Application ; Antibiotics N-SAntibiotics ; Antineoplastic and Immunosuppressive AntibioticsAntibiotics ; Chemical Structure Class ; Genetic Marker SelectionAntibiotics ; Interferes with Protein SynthesisSpectrum of Activity ; Mechanism of Action ; N
MF: C₂₃H₄₆N₆O₁₃
MW: 614.64
EINECS: 204-292-2
Density: 1.61 g/cm³
Flash Point: 514.5 °C
Boiling Point: 927.1 °C at 760 mmHg
Enthalpy of Vaporization: 153.02 kJ/mol
Storage temp.: 2-8°C
Merck: 13,6482
Following is the molecular structure of Neomycin B (CAS NO.119-04-0) is:

Neomycin B History

It was discovered in 1949 by the microbiologist Selman Waksman and his student Hubert Lechevalier at Rutgers University. It is produced naturally by the bacterium Streptomyces fradiae.

Neomycin B Uses

Neomycin B (CAS NO.119-04-0) was recommended for use in cell culture applications at 5 ml/L.

Neomycin B Production

Preparation Products is Neomycin Sulfate .

Neomycin B Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intraperitoneal	250mg/kg (250mg/kg)	"Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 1, Pg. 741, 1978.
mouse	LD50	intravenous	24mg/kg (24mg/kg)	Journal of Antibiotics. Vol. 27, Pg. 677, 1974.
mouse	LD50	oral	1250mg/kg (1250mg/kg)	"CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 1, Pg. 127, 1980.
mouse	LD50	subcutaneous	220mg/kg (220mg/kg)	"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 2, Pg. 121, 1957.

Neomycin B Safety Profile

Poison by intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes:
Harmful Xn
Risk Statements:
R42/43:May cause sensitization by inhalation and skin contact.
R63:Possible risk of harm to the unborn child.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 2
F:
F 8: Photosensitive.

Neomycin B Specification

To protect yourself, you can put on eyeshields, faceshields, full-face respirator (US), gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter.

Product Name

NEOMYCIN B