Product Name

  • Name

    Nifurpipone

  • EINECS
  • CAS No. 24632-47-1
  • Article Data3
  • CAS DataBase
  • Density 1.41g/cm3
  • Solubility
  • Melting Point 167.5°C (rough estimate)
  • Formula C12H17 N5 O4
  • Boiling Point °Cat760mmHg
  • Molecular Weight 295.298
  • Flash Point °C
  • Transport Information
  • Appearance
  • Safety Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 24632-47-1 (Nifurpipone)
  • Hazard Symbols
  • Synonyms 1-Piperazineaceticacid, 4-methyl-, (5-nitrofurfurylidene)hydrazide (8CI); 1-Piperazineaceticacid, 4-methyl-, [(5-nitro-2-furanyl)methylene]hydrazide (9CI);5-Nitro-2-furaldehyde 4-methylpiperazinoacethydrazone; 5-Nitro-2-furfuraldehydeN'-methyl-N-piperazinoacethydrazone; NP; NSC 276014; Nifurpipone; Rec 15-0122
  • PSA 106.90000
  • LogP 0.67520

Nifurpipone Chemical Properties

IUPAC Name:  2-(4-Methylpiperazin-1-yl)-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]acetamide
Synonyms of Nifurpipone (CAS NO.24632-47-1) : 1-Piperazineacetic acid, 4-methyl-, 2-[(1E)-(5-nitro-2-furanyl)methylene]hydrazide ; 2-(4-Methylpiperazin-1-yl)-N'-[(E)-(5-nitro-2-furyl)methylene]acetohydrazide ; 1-Piperazineacetic acid, 4-methyl-, ((5-nitro-2-furanyl)methylene)hydrazide (9CI) ; 2-Furaldehyde, 5-nitro-, (4-methylpiperazinylacetyl)hydrazone ; 4-Methyl-1-piperazineacetic acid (5-nitrofurfurylidene)hydrazide
InChI:InChI=1/C12H17N5O4/c1-15-4-6-16(7-5-15)9-11(18)14-13-8-10-2-3-12(21-10)17(19)20/h2-3,8H,4-7,9H2,1H3,(H,14,18)/b13-8+ 
CAS NO:24632-47-1
Molecular Formula:C12H17N5O4                                  
Molecular Weight :295.2945                                                   
Molecular Structure :
Index of Refraction: 1.634        
Surface Tension: 59.7 dyne/cm 
Density: 1.41 g/cm3 

Nifurpipone Uses

 Nifurpipone (CAS NO.24632-47-1) is synthetic antibacterial agents.

Nifurpipone Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 315mg/kg (315mg/kg)   Journal of Medicinal Chemistry. Vol. 14, Pg. 633, 1971.
mouse LD50 intravenous 295mg/kg (295mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 14(7), Pg. 1317, 1972.
mouse LD50 oral 880mg/kg (880mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Bollettino Chimico Farmaceutico. Vol. 114, Pg. 73, 1975.
rabbit LD50 oral 400mg/kg (400mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 14(7), Pg. 1317, 1972.
rat LD50 intraperitoneal 212mg/kg (212mg/kg)   Bollettino Chimico Farmaceutico. Vol. 114, Pg. 73, 1975.
rat LD50 oral 990mg/kg (990mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Bollettino Chimico Farmaceutico. Vol. 114, Pg. 73, 1975.

Nifurpipone Consensus Reports

EPA Genetic Toxicology Program.

Nifurpipone Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. When Nifurpipone (CAS NO.24632-47-1) is heated to decomposition, it emits toxic fumes of NOx.

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