Product Name

  • Name

    Nifurthiazole

  • EINECS
  • CAS No. 3570-75-0
  • Density 1.612g/cm3
  • Solubility
  • Melting Point 215.5°C (rough estimate)
  • Formula C8H6 N4 O4 S
  • Boiling Point 454.8°Cat760mmHg
  • Molecular Weight 254.226
  • Flash Point 228.9°C
  • Transport Information
  • Appearance
  • Safety Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 3570-75-0 (Nifurthiazole)
  • Hazard Symbols
  • Synonyms Formicacid, 2-[4-(5-nitro-2-furyl)-2-thiazolyl]hydrazide (7CI,8CI);Hydrazinecarboxaldehyde, 2-[4-(5-nitro-2-furanyl)-2-thiazolyl]- (9CI);2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole; AS 17665; FNT; NSC 525334;Nifurthiazol; Nifurthiazole
  • PSA 141.22000
  • LogP 3.00720

Nifurthiazole Chemical Properties

IUPAC Name: N-[[4-(5-Nitrofuran-2-yl)-1,3-thiazol-2-yl]amino]formamide
Synonyms of Nifurthiazole (CAS NO.3570-75-0) : 2-(4-(5-Nitro-2-furanyl)-2-thiazolyl)hydrazinecarboxaldehyde ; N'-[4-(5-Nitro-2-furyl)-1,3-thiazol-2-yl]formic hydrazide ; N'-[4-(5-nitrofuran-2-yl)-1,3-thiazol-2-yl]formic hydrazide ;nefurthiazole ; Thiazole, 2-(2-formylhydrazinyl)-4-(5-nitro-2-furanyl)-
InChI:InChI=1/C8H6N4O4S/c13-4-9-11-8-10-5(3-17-8)6-1-2-7(16-6)12(14)15/h1-4H,(H,9,13)(H,10,11)   
CAS NO:3570-75-0 
Molecular Formula:C8H6N4O4S               
Molecular Weight :254.2226               
Molecular Structure :
Index of Refraction: 1.679   
Surface Tension: 74.4 dyne/cm 
Density: 1.612 g/cm3 
Flash Point: 228.9 °C 
Enthalpy of Vaporization: 71.45 kJ/mol 
Boiling Point: 454.8 °C at 760 mmHg 
Vapour Pressure: 1.84E-08 mmHg at 25°C 

Nifurthiazole Uses

 Nifurthiazole (CAS NO.3570-75-0) is antimicrobial.

Nifurthiazole Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 445mg/kg (445mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)		 Antimicrobial Agents and Chemotherapy Vol. -, Pg. 268, 1962.
mouse LD50 oral 1400mg/kg (1400mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)		 Antimicrobial Agents and Chemotherapy Vol. -, Pg. 268, 1962.

Nifurthiazole Consensus Reports

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1974,p. 151.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.

Nifurthiazole Safety Profile

Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Mutation data reported. When Nifurthiazole (CAS NO.3570-75-0) is heated to decomposition, it emits very toxic fumes of NOx and SOx.

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