N-NITROSODIETHANOLAMINE

IUPAC Name: N,N-bis(2-Hydroxyethyl)nitrous amide  
Synonyms of Nitrosoimino diethanol (CAS NO.1116-54-7) : 2,2'-(Nitrosoimino)diethanol ; 2,2-(Nitrosoimino) bisethanol ; Di-(2-Hydroxyethyl)nitrosamine ; Ethanol, 2,2'-(nitrosoimino)bis-
InChI:InChI=1/C4H10N2O3/c7-3-1-6(5-9)2-4-8/h7-8H,1-4H2       
Product Categories: Nitrosamine;pharmacetical
CAS NO:1116-54-7
Molecular Formula:C₄H₁₀N₂O₃   
Molecular Weight :134.1338    
Molecular Structure :
EINECS: 214-237-4
Index of Refraction:1.498           
Surface Tension: 52.2 dyne/cm 
Density: 1.28 g/cm³ 
Flash Point: 181.1 °C 
Enthalpy of Vaporization: 72.12 kJ/mol 
Boiling Point: 375.9 °C at 760 mmHg 
Vapour Pressure: 3.46E-07 mmHg at 25°C 
Storage temp: 2-8°C
Appearance: Nitrosoimino diethanol (CAS NO.1116-54-7) is yellow to dark brown very viscous liquid with no distinct odor.
Water solubility: Nitrosoimino diethanol (CAS NO.1116-54-7) is water soluble.

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 ,1978,p. 77.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 ,1978,p. 77.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory.

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Mildly toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. See also N-NITROSO COMPOUNDS and ALCOHOL, DENATURED; ALCOHOLS, C6-12; ALCOHOLS, C9-11; ALCOHOLS, C12-13, ETHOXYLATED; ALCOHOLS, C12-15, ETHOXYLATED; ALCOHOLS, C12-16, ETHOXYLATED; ALCOHOLS, C14-15, ETHOXYLATED; ALCOHOLS, C16-18, ETHOXYLATED; ALCOHOLS, C8-10, ETHOXYLATED PROPOXYLATED; ALCOHOLS, C12-15, ETHOXYLATED PROPOXYLATED; ALCOHOLS, N.O.S..

Hazard CodesT
Risk Statements 45
R45:May cause cancer.
Safety Statements 53-45
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S53:Avoid exposure - obtain special instructions before use.
RIDADR UN 1993 3/PG 2
WGK Germany 1
RTECS KL9550000
HazardClass 3.1
PackingGroup II 

DFG MAK: Animal Carcinogen, Suspected Human Carcinogen

For occupational chemical analysis use OSHA: #31.

1.Reactivity Profile:N-Nitrosodiethanolamine can react with alkoxides.N-Nitrosodiethanolamine reacts with sulfuric acid at temperatures above 311° F.

2.Health Hazard :ACUTE/CHRONIC HAZARDS: N-Nitrosodiethanolamine may be harmful by eye or skin contact, inhalation or ingestion. It is an irritant and, when heated to decomposition, it emits toxic fumes of carbon monoxide, carbon dioxide and nitrogen oxides.