Product Name

  • Name

    N-NITROSOUREA

  • EINECS
  • CAS No. 13010-20-3
  • Density 1.82g/cm3
  • Solubility
  • Melting Point 111-111.3 °C (decomp)
  • Formula CH3 N3 O2
  • Boiling Point °Cat760mmHg
  • Molecular Weight 89.0537
  • Flash Point °C
  • Transport Information
  • Appearance
  • Safety Mutation data reported. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
  • Risk Codes
  • Molecular Structure Molecular Structure of 13010-20-3 (N-NITROSOUREA)
  • Hazard Symbols
  • Synonyms Urea,nitroso- (8CI,9CI); N-Nitrosourea; Nitrosourea; Nitrosurea
  • PSA 89.03000
  • LogP 0.42030

Nitrosourea Chemical Properties

IUPAC Name: Nitrosourea  
Synonyms of Nitrosourea (CAS NO.13010-20-3) :1-Nitrosoharnstoff ; 1-Nitrosourea ; Urea, N-nitroso- ; N-Nitrosourea
InChI:InChI=1/CH3N3O2/c2-1(5)3-4-6/h(H3,2,3,5,6)   
CAS NO:13010-20-3
Molecular Formula:C5H9N3O4
Molecular Weight :175.1427
Molecular Structure :
Index of Refraction:1.608       
Surface Tension: 91.7 dyne/cm 
Density: 1.82 g/cm

Nitrosourea Toxicity Data With Reference

1.    

cyt-mus-ipr 3200 µg/kg

    MUREAV    Mutation Research. 38 (1976),106.
2.    

spm-mus-ipr 3200 µg/kg

    MUREAV    Mutation Research. 38 (1976),106.

Nitrosourea Safety Profile

Mutation data reported. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.

Nitrosourea Specification

 Nitrosourea (CAS NO.13010-20-3) compounds are DNA alkylating agents and are often used in chemotherapy. Nitrosourea (CAS NO.13010-20-3) compounds are lipophilic and thus can cross the blood-brain barrier, making them useful in the treatment of brain tumors such as glioblastoma multiforme

 Some Nitrosoureas (e.g. Lomustine) have been associated with the development of interstitial lung disease.

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