(5alpha)-4,5-epoxy-3,14-dihydroxymorphinan-6-one

The Noroxymorphone is an organic compound with the formula C₁₆H₁₇NO₄. The systematic name of this chemical is (5α)-3,14-dihydroxy-4,5-epoxymorphinan-6-one. With the CAS registry number 33522-95-1, it is also named as 14-Hydroxydihydronormorphinone. The product's categories are Intermediates & Fine Chemicals; Metabolites & Impurities; Pharmaceuticals.

Physical properties about Noroxymorphone are: (1)ACD/LogP: -0.239; (2)ACD/LogD (pH 5.5): -3.09; (3)ACD/LogD (pH 7.4): -1.59; (4)ACD/BCF (pH 5.5): 1.00; (5)ACD/BCF (pH 7.4): 1.00; (6)ACD/KOC (pH 5.5): 1.00; (7)ACD/KOC (pH 7.4): 1.00; (8)#H bond acceptors: 5; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 2; (11)Index of Refraction: 1.722; (12)Molar Refractivity: 73.421 cm³; (13)Molar Volume: 185.378 cm³; (14)Polarizability: 29.107 10-24cm³; (15)Surface Tension: 81.6669998168945 dyne/cm; (16)Density: 1.55 g/cm³; (17)Flash Point: 287.689 °C; (18)Enthalpy of Vaporization: 87.61 kJ/mol; (19)Boiling Point: 552.082 °C at 760 mmHg

Preparation of Noroxymorphone: This chemical can be prepared by 14-acetylnoroxymorphone hydrochloride. This reaction will need reagent 25percent aq. sulphuric acid. The reaction time is 5 hours with reaction temperature of 100 - 102 °C. The yield is about 88%

Uses of Noroxymorphone: It can be used to produce N-(2-methylallyl)oxymorphone at temperature of 80 °C. It will need reagent NaHCO₃ and solvent dimethylformamide with reaction time of 2 hours. The yield is about 85%.

You can still convert the following datas into molecular structure:
(1)InChI=1S/C16H17NO4/c18-9-2-1-8-7-11-16(20)4-3-10(19)14-15(16,5-6-17-11)12(8)13(9)21-14/h1-2,11,14,17-18,20H,3-7H2/t11-,14-,15+,16-/m1/s1;
(2)InChIKey=HLMSIZPQBSYUNL-BQDHKBFISA-N ;
(3)Smilesc1cc(c2c3[C@@]45[C@H](C(CC[C@@]4([C@H](NCC5)Cc13)O)=O)O2)O；