O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine

The O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine, with the CAS registry number 6723-30-4, has the IUPAC name O-(oxan-2-yl)hydroxylamine. It belongs to the following product categories: Building Blocks; Heterocyclic Building Blocks; Pyrans. And the molecular formula of the chemical is C₅H₁₁NO₂.

The physical properties of O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine are as followings: (1)ACD/LogP: 0.01; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.01; (4)ACD/LogD (pH 7.4): 0.01; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 24.1; (8)ACD/KOC (pH 7.4): 24.24; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 21.7 Å²; (13)Index of Refraction: 1.463; (14)Molar Refractivity: 30.23 cm³; (15)Molar Volume: 109.6 cm³; (16)Polarizability: 11.98×10^-24cm³; (17)Surface Tension: 36.2 dyne/cm; (18)Density: 1.06 g/cm³; (19)Flash Point: 94.5 °C; (20)Enthalpy of Vaporization: 44.56 kJ/mol; (21)Boiling Point: 209.3 °C at 760 mmHg; (22)Vapour Pressure: 0.204 mmHg at 25°C.

Uses of O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine: It can react with benzoyl chloride to produce N-tetrahydropyran-2-yloxy-benzamide. This reaction will need reagent Na₂CO₃, and the solvents H₂O and CHCl₃. The reaction time is 15 minutes, and the yield is about 60%.   

You should be cautious while dealing with this chemical. It irritates to eyes, respiratory system and skin. Therefore, you had better take the following instructions: Wear suitable protective clothing, and if in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O(N)C1OCCCC1
(2)InChI: InChI=1/C5H11NO2/c6-8-5-3-1-2-4-7-5/h5H,1-4,6H2
(3)InChIKey: NLXXVSKHVGDQAT-UHFFFAOYAQ