-
Name
Ophthazin
- EINECS 207-605-0
- CAS No. 484-23-1
- Article Data14
- CAS DataBase
- Density 1.543 g/cm3
- Solubility
- Melting Point 180ºC
- Formula C8H10 N6
- Boiling Point 648.3 °C at 760 mmHg
- Molecular Weight 190.208
- Flash Point 345.9 °C
- Transport Information
- Appearance
- Safety Poison by intravenous route. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms 1,4-Phthalazinedione,2,3-dihydro-, dihydrazone (9CI); Phthalazine, 1,4-dihydrazino- (7CI,8CI);1,4-Dihydrazinophthalazine; C 7441; Cassella 532; Dihydralazin; Dihydralazine;Dihydrazinophthalazine; Hypopresol; NSC 526654; Nepresol; Nepresolin;Nepressol; Ophthazin; Tonolysin
- PSA 108.34000
- LogP 0.44540
OPHTHAZIN Chemical Properties
MF: C8H10N6
MW: 190.21
EINECS: 207-605-0
Density: 1.543 g/cm3
Flash Point: 345.9 °C
Index of Refraction: 1.899
Appearance: Orange needle crystal
Enthalpy of Vaporization: 95.58 kJ/mol
Boiling Point: 648.3 °C at 760 mmHg
Vapour Pressure: 1.09E-16 mmHg at 25°C
IUPAC Name: (4-Hydrazinylphthalazin-1-yl)hydrazine
Solubility Ophthazin (484-23-1): Slightly soluble in water, soluble in water or ethanol
Synonyms: 1,4-Dihydrazinonaphthalazine ; 1,4-Dihydrazino-phthalazin ; 2,3-Dihydro-1,4-phthalazinedionedihydrazone ; 4-Phthalazinedione,2,3-dihydro-Dihydrazone ; C7441 ; Cassella532 ; Dihydralazin
Following is the molecular structure of Ophthazin (484-23-1):
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OPHTHAZIN Uses
Ophthazin (484-23-1) for blood. Direct effect on peripheral vascular, reduce blood pressure especially suitable for renal insufficiency, and diastolic blood pressure patients with high, rarely orthostatic hypotension. Also can be used as high-molecular compounds containing carbonyl of chain, complexing agent and applied in analytical chemistry.
OPHTHAZIN Toxicity Data With Reference
| 1. | ivn-mus LD50:300 mg/kg | EJMCA5 European Journal of Medicinal Chemistry. Chimie Therapeutique. 11 (1976),107. |
OPHTHAZIN Safety Profile
Poison by intravenous route. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx.
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