Oleandomycin phosphate supplier

Name
OLEANDOMYCIN PHOSPHATE
EINECS
CAS No. 7060-74-4
Density
Solubility
Melting Point 145-147℃
Formula C₃₅H₆₁NO₁₂•H₃O₄P
Boiling Point
Molecular Weight 785.97
Flash Point
Transport Information
Appearance
Safety Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of PO_x and NO_x. See also PHOSPHATES.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms OleandomycinPhosphate
PSA 253.55000
LogP 0.97990

Synthetic route

: 7060-74-4
oleandomycin phosphate

: 64774-87-4
8-methylene-oleandomycin

Conditions

Conditions	Yield
With chromium dichloride In water; acetone at 20℃; for 0.75h;

Oleandomycin phosphate Chemical Properties

IUPAC Name: (3S,5S,6S,7R,8S,9R,12R,13R,14S,15R)-6-[(2S,3R,4S,6R)-4-Dimethylamino-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-14-hydroxy-8-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyl-tetrahydropyran-2-yl]oxy-5,7,9,12,13,15-hexamethyl-1,11-dioxaspiro[2.13]hexadecane-10,16-dione; phosphoric acid
Synonyms: (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-Hydroxy-5,7,8,11,13,15-hexamethyl-4,10-dioxo-14-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1,9-dioxaspiro[2.13]hexadec-12-yl 2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranoside phosphate (1:1) ; 1,9-Dioxaspiro[2.13]hexadecane-4,10-dione, 12-[(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)oxy]-6-hydroxy-5,7,8,11,13,15-hexamethyl-14-[[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy]-, (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-, phosphate (1:1) (salt) ; Matromycin (phosphate) ; Oleandomycin phosphate (JAN)
CAS NO:7060-74-4
Molecular Formula of Oleandomycin phosphate (CAS NO.7060-74-4) :C₃₅H₆₄NO₁₆P
Molecular Weight of Oleandomycin phosphate (CAS NO.7060-74-4) :785.85
Molecular Structure of Oleandomycin phosphate (CAS NO.7060-74-4) :
EINECS: 230-351-7
Flash Point: 518 °C
Enthalpy of Vaporization: 153.99 kJ/mol
Boiling Point: 932.9 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C
Storage temp: 0-6°C

Oleandomycin phosphate Uses

Oleandomycin phosphate (CAS NO.7060-74-4) is effective against staphylococci, streptococci, pneumococci, and some Gram-negative bacteria.

Oleandomycin phosphate Production

Oleandomycin phosphate (CAS NO.7060-74-4) is an antibiotic substance produced by species of Streptomyces .antibioticus.

Oleandomycin phosphate Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	400mg/kg (400mg/kg)		Drugs in Japan Vol. 6, Pg. 164, 1982.
mouse	LD50	oral	4gm/kg (4000mg/kg)		Drugs in Japan Vol. 6, Pg. 164, 1982.
mouse	LD50	subcutaneous	1gm/kg (1000mg/kg)		Drugs in Japan Vol. 6, Pg. 164, 1982.
rat	LD50	intravenous	480mg/kg (480mg/kg)	BEHAVIORAL: ATAXIA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Antibiotics and Chemotherapy Vol. 7, Pg. 419, 1957.

Oleandomycin phosphate Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of PO_x and NO_x. See also PHOSPHATES.
Safety Statements 22-24/25
S22:Do not breathe dust.
S24/25:Avoid contact with skin and eyes.
RIDADR UN2811 6.1/PG 2
RTECS RJ9800000

Product Name

OLEANDOMYCIN PHOSPHATE